YRC Public Data Repository - Protein Structure Prediction

Protein:	RIHB_ECOLI, YEIK...
Organism:	Escherichia coli
Length:	313 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIHB_ECOLI, YEIK....

Description	E-value	Query Range	Subject Range
gi\|83846473, gi\|... - gi\|83942380\|ref\|ZP_00954841.1\| inosine-uridine preferring nucleoside hydrolase [Sulfitobacter sp. EE...	386.0	[0..1]	[309..1]
gi\|83953600, gi\|... - gi\|83953600\|ref\|ZP_00962321.1\| inosine-uridine preferring nucleoside hydrolase [Sulfitobacter sp. NA...	384.0	[0..1]	[309..1]
gi\|13472783, gi\|... - gi\|14023530\|dbj\|BAB50136.1\| nucleoside hydrolase [Mesorhizobium loti MAFF303099], gi\|13472783\|ref\|NP...	382.0	[0..2]	[309..3]
RIHB_SHISS - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Shigella sonnei (strain Ss046) GN=rihB PE=3 SV=... gi\|194420180, gi... - gi\|194431355\|ref\|ZP_03063647.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Shig...	380.0	[0..1]	[313..1]
gi\|208726582, gi... - gi\|208806781\|ref\|ZP_03249118.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Esch... gi\|195935541 - gi\|195935541\|ref\|ZP_03080923.1\| ribonucleoside hydrolase 2 [Escherichia coli O157:H7 str. EC4024] RIHB_ECO57 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O157:H7 GN=rihB PE=3 SV=1 gi\|168801143, gi... - gi\|189376619\|gb\|EDU95035.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|209766136, gi... - pir\|\|H85854 hypothetical protein yeiK [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|189002068, gi... - gi\|189002068\|gb\|EDU71054.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|15832308, gi\|... - gi\|15832308\|ref\|NP_311081.1\| ribonucleoside hydrolase 2 [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|217320026, gi... - gi\|217327659\|ref\|ZP_03443742.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Esch... gi\|12516485, gi\|... - gi\|15802718\|ref\|NP_288745.1\| ribonucleoside hydrolase 2 [Escherichia coli O157:H7 EDL933], gi\|125164... RIHB_ECO5E - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O157:H7 (strain EC4115 / EHEC)... gi\|208738579, gi... - gi\|208818456\|ref\|ZP_03258776.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Esch... gi\|208735677, gi... - gi\|208814400\|ref\|ZP_03255729.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Esch... gi\|188013601, gi... - gi\|188013601\|gb\|EDU51723.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|187771342, gi... - gi\|187771342\|gb\|EDU35186.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|189362906, gi... - gi\|189362906\|gb\|EDU81325.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|189366053, gi... - gi\|189366053\|gb\|EDU84469.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|168758825, gi... - gi\|189354421\|gb\|EDU72840.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Escheric... gi\|254593461, gi... - gi\|254794061\|ref\|YP_003078898.1\| ribonucleoside hydrolase 2 [Escherichia coli O157:H7 str. TW14359],...	379.0	[0..1]	[313..1]
RIHB_ECOL6 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 70... gi\|190909723, gi... - gi\|75242979\|ref\|ZP_00726685.1\| COG1957: Inosine-uridine nucleoside N-ribohydrolase [Escherichia coli... RIHB_ECOUT - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli (strain UTI89 / UPEC) GN=rihB ... sp\|B7UFH8\|RIHB_ECO27 - Pyrimidine-specific ribonucleoside hydrolase rihB OS=Escherichia coli O127:H6 (strain E2348/69 / EPE... RIHB_ECOL6 - Pyrimidine-specific ribonucleoside hydrolase rihB OS=Escherichia coli O6 GN=rihB PE=3 SV=1 gi\|227835567, gi... - gi\|227887217\|ref\|ZP_04005022.1\| ribosylpyrimidine nucleosidase [Escherichia coli 83972], gi\|22783556... gi\|237704630, gi... - gi\|237704630\|ref\|ZP_04535111.1\| ribonucleoside hydrolase 2 [Escherichia sp. 3_2_53FAA], gi\|226900996... RIHB_ECOL5 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC)... RIHB_ESCF3 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia fergusonii (strain ATCC 35469 / DSM... RIHB_ECO27 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O127:H6 (strain E2348/69 / EPE... RIHB_ECO81 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O81 (strain ED1a) GN=rihB PE=3... RIHB_ECO45 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN... RIHB_ECOK1 - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O1:K1 / APEC GN=rihB PE=3 SV=1	379.0	[0..1]	[313..1]
gi\|209766134, gi... - gi\|49258563\|pdb\|1Q8F\|D Chain D, Crystal Structure Of The E.Coli Pyrimidine Nucleoside Hydrolase Yeik...	378.0	[0..1]	[313..1]
gi\|146277154, gi... - gi\|83369561\|ref\|ZP_00914414.1\| inosine-uridine preferring nucleoside hydrolase [Rhodobacter sphaeroi...	378.0	[0..2]	[309..3]
gi\|124526739, gi... - gi\|124526739\|ref\|ZP_01698648.1\| Inosine/uridine-preferring nucleoside hydrolase [Escherichia coli B]... RIHB_ECO8A - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O8 (strain IAI1) GN=rihB PE=3 ... gi\|188494403, gi... - gi\|75514499\|ref\|ZP_00736777.1\| COG1957: Inosine-uridine nucleoside N-ribohydrolase [Escherichia coli... RIHB_ECOHS - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli O9:H4 (strain HS) GN=rihB PE=3... gi\|194436179, gi... - gi\|83588143\|ref\|ZP_00926768.1\| COG1957: Inosine-uridine nucleoside N-ribohydrolase [Escherichia coli... RIHB_ECOLC - Pyrimidine-specific ribonucleoside hydrolase RihB OS=Escherichia coli (strain ATCC 8739 / DSM 1576 /...	378.0	[0..1]	[313..1]
gi\|86606550, gi\|... - gi\|86606550\|ref\|YP_475313.1\| inosine-uridine preferring nucleoside hydrolase family protein [Synecho... gi\|86606550 - gi\|86606550\|ref\|YP_475313.1\| Inosine-uridine preferring nucleoside hydrolase family protein [Cyanoba...	378.0	[0..5]	[309..3]

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Predicted Domain #1

Region A:
Residues: [1-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKRKIILDC DPGHDDAIAI MMAAKHPAID LLGITIVAGN QTLDKTLING LNVCQKLEIN  60
   61 VPVYAGMPQP IMRQQIVADN IHGETGLDGP VFEPLTRQAE STHAVKYIID TLMASDGDIT 120
  121 LVPVGPLSNI AVAMRMQPAI LPKIREIVLM GGAYGTGNFT PSAEFNIFAD PEAARVVFTS 180
  181 GVPLVMMGLD LTNQTVCTPD VIARMERAGG PAGELFSDIM NFTLKTQFEN YGLAGGPVHD 240
  241 ATCIGYLINP DGIKTQEMYV EVDVNSGPCY GRTVCDELGV LGKPANTKVG ITIDTDWFWG 300
  301 LVEECVRGYI KTH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	106.0
Match:	1q8fA
Description:	Crystal Structure of the E.coli pyrimidine nucleoside hydrolase yeiK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
purine nucleosidase activity	5.00131823185644	bayes_pls_golite062009
uridine nucleosidase activity	4.52347848055672	bayes_pls_golite062009
nicotinamide riboside hydrolase activity	2.8334656966172	bayes_pls_golite062009
hydrolase activity	2.43029583892337	bayes_pls_golite062009
nicotinic acid riboside hydrolase activity	2.34858421255381	bayes_pls_golite062009
ribosylpyrimidine nucleosidase activity	1.87397458605934	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	1.79122605877364	bayes_pls_golite062009
catalytic activity	1.41033217274476	bayes_pls_golite062009
binding	1.30080028582629	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	0.90955247890873	bayes_pls_golite062009
protein binding	0.38298446125287	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: