YRC Public Data Repository - Protein Structure Prediction

Protein:	YEIC_ECOLI
Organism:	Escherichia coli
Length:	313 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEIC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|28203058, gi\|... - gi\|28210620\|ref\|NP_781564.1\| ribokinase [Clostridium tetani E88], gi\|28203058\|gb\|AAO35501.1\| ribokin...	261.0	[0..2]	[308..1]
gi\|20515184, gi\|... - gi\|20806728\|ref\|NP_621899.1\| ribokinase family sugar kinase [Thermoanaerobacter tengcongensis MB4], ... gi\|20806728 - gi\|20806728\|ref\|NP_621899.1\| Sugar kinase, ribokinase family [Thermoanaerobacter tengcongensis MB4] gi\|254478103, gi... - gi\|254478103\|ref\|ZP_05091486.1\| ribokinase [Carboxydibrachium pacificum DSM 12653], gi\|223490092\|ref...	255.0	[0..4]	[308..1]
gi\|242258203, gi... - gi\|242258203\|ref\|ZP_04803029.1\| ribokinase [Thermoanaerobacter sp. X513], gi\|242230274\|gb\|EES32659.1... gi\|241904638, gi... - gi\|241904638\|ref\|ZP_04789317.1\| ribokinase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi\|2418... gi\|167038425, gi... - gi\|76797420\|ref\|ZP_00779739.1\| Ribokinase, bacterial [Thermoanaerobacter ethanolicus ATCC 33223], gi... gi\|167038832, gi... - gi\|167038832\|ref\|YP_001661817.1\| ribokinase [Thermoanaerobacter sp. X514], gi\|166853072\|gb\|ABY91481....	250.0	[0..4]	[308..1]
gi\|106882307, gi... - gi\|119944129\|ref\|YP_941809.1\| ribokinase [Psychromonas ingrahamii 37], gi\|119862733\|gb\|ABM02210.1\| r...	250.0	[0..4]	[308..1]
gi\|52424338, gi\|... - gi\|52424338\|ref\|YP_087475.1\| RbsK protein [Mannheimia succiniciproducens MBEL55E], gi\|52306390\|gb\|AA...	246.0	[0..4]	[310..5]
gi\|27469004, gi\|... - gi\|27469004\|ref\|NP_765641.1\| ribokinase [Staphylococcus epidermidis ATCC 12228], gi\|27316553\|gb\|AAO0...	245.0	[0..2]	[307..1]
gi\|57865524, gi\|... - gi\|57865524\|ref\|YP_189656.1\| ribokinase [Staphylococcus epidermidis RP62A], gi\|57636182\|gb\|AAW52970....	245.0	[0..2]	[307..1]
gi\|91224727, gi\|... - gi\|91224727\|ref\|ZP_01259987.1\| ribokinase [Vibrio alginolyticus 12G01], gi\|91190273\|gb\|EAS76542.1\| r...	244.0	[0..4]	[308..1]
gi\|227119309, gi... - gi\|75824935\|ref\|ZP_00754371.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae O395], gi\|... gi\|121630645, gi... - gi\|75815451\|ref\|ZP_00745959.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae V52], gi\|1... gi\|11356074 - pir\|\|D82497 ribokinase VCA0131 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|121586869, gi... - gi\|121586869\|ref\|ZP_01676650.1\| ribokinase [Vibrio cholerae 2740-80], gi\|121548912\|gb\|EAX58953.1\| ri... gi\|153221870, gi... - gi\|153221870\|ref\|ZP_01952735.1\| ribokinase [Vibrio cholerae MAK 757], gi\|124119363\|gb\|EAY38106.1\| ri... gi\|126511740, gi... - gi\|153817698\|ref\|ZP_01970365.1\| ribokinase [Vibrio cholerae NCTC 8457], gi\|126511740\|gb\|EAZ74334.1\| ... gi\|227010899, gi... - gi\|227811757\|ref\|YP_002811767.1\| ribokinase [Vibrio cholerae M66-2], gi\|227010899\|gb\|ACP07110.1\| rib... gi\|9657519, gi\|1... - gi\|9657519\|gb\|AAF96045.1\| ribokinase [Vibrio cholerae O1 biovar eltor str. N16961], gi\|15600902\|ref\|... gi\|75830920, gi\|... - gi\|75830920\|ref\|ZP_00760190.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae MO10], gi\|... gi\|229357053, gi... - gi\|229506702\|ref\|ZP_04396211.1\| ribokinase [Vibrio cholerae BX 330286], gi\|229357053\|gb\|EEO21971.1\| ... gi\|229352949, gi... - gi\|229510504\|ref\|ZP_04399984.1\| ribokinase [Vibrio cholerae B33], gi\|229352949\|gb\|EEO17889.1\| riboki... gi\|229345401, gi... - gi\|229517365\|ref\|ZP_04406810.1\| ribokinase [Vibrio cholerae RC9], gi\|229345401\|gb\|EEO10374.1\| riboki... gi\|229371661, gi... - gi\|229605175\|ref\|YP_002875879.1\| ribokinase [Vibrio cholerae MJ-1236], gi\|229371661\|gb\|ACQ62083.1\| r...	244.0	[0..4]	[309..1]
gi\|28809384, gi\|... - gi\|28900938\|ref\|NP_800593.1\| ribokinase [Vibrio parahaemolyticus RIMD 2210633], gi\|28809384\|dbj\|BAC6... gi\|28809384 - gi\|28809384\|dbj\|BAC62426.1\| ribokinase [Vibrio parahaemolyticus RIMD 2210633] gi\|149750024, gi... - gi\|153836675\|ref\|ZP_01989342.1\| ribokinase [Vibrio parahaemolyticus AQ3810], gi\|149750024\|gb\|EDM6076...	243.0	[0..4]	[308..1]

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Predicted Domain #1

Region A:
Residues: [1-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREKDYVVII GSANIDVAGY SHESLNYADS NPGKIKFTPG GVGRNIAQNL ALLGNKAWLL  60
   61 SAVGSDFYGQ SLLTQTNQSG VYVDKCLIVP GENTSSYLSL LDNTGEMLVA INDMNISNAI 120
  121 TAEYLAQHGE FIQRAKVIVA DCNISEEALA WILDNAANVP VFVDPVSAWK CVKVRDRLNQ 180
  181 IHTLKPNRLE AETLSGIALS GREDVAKVAA WFHQHGLNRL VLSMGGDGVY YSDISGESGW 240
  241 SAPIKTNVIN VTGAGDAMMA GLASCWVDGM PFAESVRFAQ GCSSMALSCE YTNNPDLSIA 300
  301 NVISLVENAE CLN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.39794
Match:	1vm7A
Description:	Crystal structure of Ribokinase (TM0960) from Thermotoga maritima at 2.15 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribokinase activity	4.13972810632318	bayes_pls_golite062009
carbohydrate kinase activity	3.53872211951287	bayes_pls_golite062009
kinase activity	2.28531824242987	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.27980720248925	bayes_pls_golite062009
transferase activity	2.15883296431019	bayes_pls_golite062009
phosphofructokinase activity	1.98381934960918	bayes_pls_golite062009
catalytic activity	1.74474587246986	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.673555832721854	bayes_pls_golite062009
binding	0.2717506679077	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: