YRC Public Data Repository - Protein Structure Prediction

Protein:	MDTD_ECOLI, YEGB...
Organism:	Escherichia coli
Length:	471 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDTD_ECOLI, YEGB....

Description	E-value	Query Range	Subject Range
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	288.0	[0..4]	[435..596]
gi\|46107656, gi\|... - gi\|46107656\|ref\|XP_380887.1\| hypothetical protein FG00711.1 [Gibberella zeae PH-1], gi\|42547814\|gb\|E...	286.0	[0..25]	[415..1460]
gi\|70725707, gi\|... - gi\|70725707\|ref\|YP_252621.1\| hypothetical protein SH0706 [Staphylococcus haemolyticus JCSC1435], gi\|...	279.0	[0..8]	[424..179]
gi\|25498023 - pir\|\|D96902 MDR-type permease [imported] - Clostridium acetobutylicum gi\|15893318, gi\|... - gi\|15893318\|ref\|NP_346667.1\| MDR-type permease [Clostridium acetobutylicum ATCC 824], gi\|15022839\|gb...	265.0	[0..6]	[415..4]
gi\|251804540, gi... - gi\|251811941\|ref\|ZP_04826414.1\| MFS family major facilitator transporter, multidrug:cation symporter... gi\|57636029, gi\|... - gi\|57865371\|ref\|YP_189502.1\| EmrB/QacA family drug resistance transporter [Staphylococcus epidermidi...	252.0	[0..8]	[424..151]
gi\|27316398, gi\|... - gi\|27468850\|ref\|NP_765487.1\| multidrug resistance protein [Staphylococcus epidermidis ATCC 12228], g...	251.0	[0..8]	[424..151]
gi\|54026956, gi\|... - gi\|54026956\|ref\|YP_121198.1\| putative transporter [Nocardia farcinica IFM 10152], gi\|54018464\|dbj\|BA...	250.0	[0..2]	[421..12]
gi\|73661859, gi\|... - gi\|73661859\|ref\|YP_300640.1\| major facilitator superfamily permease [Staphylococcus saprophyticus su...	246.0	[0..11]	[425..140]
gi\|115250420, gi... - gi\|126698983\|ref\|YP_001087880.1\| putative transporter [Clostridium difficile 630], gi\|115250420\|emb\|...	242.0	[0..4]	[419..16]
gi\|90205974, gi\|... - gi\|90205974\|ref\|ZP_01208611.1\| Drug resistance transporter EmrB/QacA subfamily [Mycobacterium vanbaa...	240.0	[0..8]	[471..68]

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Predicted Domain #1

Region A:
Residues: [1-471]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDLPDSTRW QLWIVAFGFF MQSLDTTIVN TALPSMAQSL GESPLHMHMV IVSYVLTVAV  60
   61 MLPASGWLAD KVGVRNIFFT AIVLFTLGSL FCALSGTLNE LLLARALQGV GGAMMVPVGR 120
  121 LTVMKIVPRE QYMAAMTFVT LPGQVGPLLG PALGGLLVEY ASWHWIFLIN IPVGIIGAIA 180
  181 TLLLMPNYTM QTRRFDLSGF LLLAVGMAVL TLALDGSKGT GLSPLTIAGL VAVGVVALVL 240
  241 YLLHARNNNR ALFSLKLFRT RTFSLGLAGS FAGRIGSGML PFMTPVFLQI GLGFSPFHAG 300
  301 LMMIPMVLGS MGMKRIVVQV VNRFGYRRVL VATTLGLSLV TLLFMTTALL GWYYVLPFVL 360
  361 FLQGMVNSTR FSSMNTLTLK DLPDNLASSG NSLLSMIMQL SMSIGVTIAG LLLGLFGSQH 420
  421 VSVDSGTTQT VFMYTWLSMA LIIALPAFIF ARVPNDTHQN VAISRRKRSA Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.30103
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	2.54286095434601	bayes_pls_golite062009
transmembrane transporter activity	2.01247278444729	bayes_pls_golite062009
substrate-specific transporter activity	1.77039368764865	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.66673693200184	bayes_pls_golite062009
active transmembrane transporter activity	0.33203350453105	bayes_pls_golite062009
polyol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.2309068592963	bayes_pls_golite062009
ion transmembrane transporter activity	0.18188709249385	bayes_pls_golite062009
binding	0.105551689569449	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	1.26964387230144E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: