YRC Public Data Repository - Protein Structure Prediction

Protein:	YECD_ECOLI
Organism:	Escherichia coli
Length:	199 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YECD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|19886895, gi\|... - gi\|20093942\|ref\|NP_613789.1\| nicotinamidase-like amidase [Methanopyrus kandleri AV19], gi\|19886895\|g...	182.0	[0..21]	[196..3]
gi\|27381262, gi\|... - gi\|27381262\|ref\|NP_772791.1\| isochorismatase family protein [Bradyrhizobium japonicum USDA 110], gi\|...	180.0	[0..3]	[199..11]
gi\|83943377, gi\|... - gi\|83943377\|ref\|ZP_00955836.1\| hypothetical isochorismatase family protein [Sulfitobacter sp. EE-36]...	178.0	[0..1]	[199..1]
gi\|146408145, gi... - gi\|78695303\|ref\|ZP_00859815.1\| conserved hypothetical isochorismatase family protein [Bradyrhizobium...	177.0	[0..3]	[199..11]
gi\|7429496 - pir\|\|G69518 isochorismatase (entB) homolog - Archaeoglobus fulgidus gi\|11499734, gi\|... - gi\|2648379\|gb\|AAB89104.1\| isochorismatase (entB) [Archaeoglobus fulgidus DSM 4304], gi\|11499734\|ref\|...	177.0	[0..21]	[196..3]
gi\|5458403, gi\|7... - pir\|\|F75073 pyrazinamidase/nicotinamidase PAB1720 - Pyrococcus abyssi (strain Orsay), gi\|5458403\|em... gi\|5458403, gi\|1... - gi\|5458403\|emb\|CAB49891.1\| Amidase related to nicotinamidase [Pyrococcus abyssi GE5], gi\|14521185\|re...	176.0	[0..21]	[191..5]
gi\|42542991, gi\|... - gi\|42542991\|pdb\|1J2R\|D Chain D, Crystal Structure Of Escherichia Coli Gene Product Yecd At 1.3 A Res...	176.0	[0..1]	[199..1]
gi\|74311803, gi\|... - gi\|74311803\|ref\|YP_310222.1\| hypothetical protein SSON_1274 [Shigella sonnei Ss046], gi\|73855280\|gb\|...	176.0	[0..1]	[199..1]
gi\|86606564, gi\|... - gi\|86606564\|ref\|YP_475327.1\| isochorismatase family protein [Synechococcus sp. JA-3-3Ab], gi\|8655510... gi\|86606564 - gi\|86606564\|ref\|YP_475327.1\| isochorismatase family protein [Cyanobacteria bacterium Yellowstone A-P...	175.0	[0..3]	[199..10]
gi\|91778735, gi\|... - gi\|91778735\|ref\|YP_553943.1\| isochorismatase family protein [Burkholderia xenovorans LB400], gi\|9169...	175.0	[0..3]	[199..10]

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Predicted Domain #1

Region A:
Residues: [1-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRHDFVFSGV IMLELNAKTT ALVVIDLQEG ILPFAGGPHT ADEVVNRAGK LAAKFRASGQ  60
   61 PVFLVRVGWS ADYAEALKQP VDAPSPAKVL PENWWQHPAA LGATDSDIEI IKRQWGAFYG 120
  121 TDLELQLRRR GIDTIVLCGI STNIGVESTA RNAWELGFNL VIAEDACSAA SAEQHNNSIN 180
  181 HIYPRIARVR SVEEILNAL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.522879
Match:	1j2rA
Description:	Crystal structure of Escherichia coli gene product Yecd at 1.3 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.36249099970982	bayes_pls_golite062009
hydrolase activity	0.171018591079791	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: