YRC Public Data Repository - Protein Structure Prediction

Protein:	YDJE_ECOLI
Organism:	Escherichia coli
Length:	452 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDJE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|91078244 - gi\|91078244\|ref\|XP_970364.1\| PREDICTED: similar to CG10960-PB, isoform B [Tribolium castaneum]	296.0	[0..20]	[452..688]
gi\|49527412 - gi\|49527412\|emb\|CAG61052.1\| unnamed protein product [Candida glabrata] gi\|50291337, gi\|... - gi\|50291337\|ref\|XP_448101.1\| unnamed protein product [Candida glabrata], gi\|49527412\|emb\|CAG61052.1\|...	293.0	[0..21]	[451..120]
gi\|90307566, gi\|... - gi\|90307566\|gb\|EAS37197.1\| hypothetical protein CIMG_02551 [Coccidioides immitis RS], gi\|119196353\|r...	288.0	[0..1]	[451..233]
gi\|169764102 - gi\|169764102\|ref\|XP_001727951.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83770979 - gi\|83770979\|dbj\|BAE61112.1\| unnamed protein product [Aspergillus oryzae]	283.0	[0..1]	[451..192]
gi\|125807904, gi... - gi\|54635731\|gb\|EAL25134.1\| GA15593-PA [Drosophila pseudoobscura], gi\|125807904\|ref\|XP_001360559.1\| G...	283.0	[0..2]	[450..379]
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	281.0	[0..6]	[450..1028]
SNF3 - Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmemb... SNF3_YEAST - High-affinity glucose transporter SNF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=S...	281.0	[0..23]	[451..100]
gi\|42555201, gi\|... - gi\|46126945\|ref\|XP_388026.1\| hypothetical protein FG07850.1 [Gibberella zeae PH-1], gi\|42555201\|gb\|E...	273.0	[0..15]	[449..1513]
CG30035-PA - This gene is referred to in FlyBase by the symbol Dmel\CG30035 (CG30035, FBgn0050035). It is a prote...	273.0	[0..2]	[450..378]
TRET1_AEDAE - Facilitated trehalose transporter Tret1 OS=Aedes aegypti GN=Tret1 PE=3 SV=1	271.0	[0..2]	[450..327]

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Predicted Domain #1

Region A:
Residues: [1-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQYDQIGAR LDRLPLARFH YRIFGIISFS LLLTGFLSYS GNVVLAKLVS NGWSNNFLNA  60
   61 AFTSALMFGY FIGSLTGGFI GDYFGRRRAF RINLLIVGIA ATGAAFVPDM YWLIFFRFLM 120
  121 GTGMGALIMV GYASFTEFIP ATVRGKWSAR LSFVGNWSPM LSAAIGVVVI AFFSWRIMFL 180
  181 LGGIGILLAW FLSGKYFIES PRWLAGKGQI AGAECQLREV EQQIEREKSI RLPPLTSYQS 240
  241 NSKVKVIKGT FWLLFKGEML RRTLVAITVL IAMNISLYTI TVWIPTIFVN SGIDVDKSIL 300
  301 MTAVIMIGAP VGIFIAALII DHFPRRLFGS TLLIIIAVLG YIYSIQTTEW AILIYGLVMI 360
  361 FFLYMYVCFA SAVYIPELWP THLRLRGSGF VNAVGRIVAV FTPYGVAALL THYGSITVFM 420
  421 VLGVMLLLCA LVLSIFGIET RKVSLEEISE VN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.154902
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	2.54286095434601	bayes_pls_golite062009
transmembrane transporter activity	2.01247278444729	bayes_pls_golite062009
substrate-specific transporter activity	1.77039368764865	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.66673693200184	bayes_pls_golite062009
active transmembrane transporter activity	0.33203350453105	bayes_pls_golite062009
polyol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.2309068592963	bayes_pls_golite062009
ion transmembrane transporter activity	0.18188709249385	bayes_pls_golite062009
binding	0.105551689569449	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	1.26964387230144E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: