YRC Public Data Repository - Protein Structure Prediction

Protein:	YDEV_ECOLI
Organism:	Escherichia coli
Length:	530 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDEV_ECOLI.

Description	E-value	Query Range	Subject Range
GLPK2_THEMA, GLK... - Glycerol kinase 2 OS=Thermotoga maritima GN=glpK2 PE=3 SV=2, (Q9X1E4) Glycerol kinase 2 (EC 2.7.1.30... GLPK2_THEMA - Glycerol kinase 2 OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=glpK2 ...	523.0	[0..12]	[518..2]
gi\|254479176, gi... - gi\|254479176\|ref\|ZP_05092524.1\| glycerol kinase [Carboxydibrachium pacificum DSM 12653], gi\|22348899... GLPK_CALS4 - Glycerol kinase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 ... GLPK_THETN - Glycerol kinase OS=Thermoanaerobacter tengcongensis GN=glpK PE=3 SV=1	512.0	[0..12]	[518..3]
GLPK_CARHZ - Glycerol kinase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=gl...	509.0	[0..10]	[516..2]
gi\|242257967, gi... - gi\|242257967\|ref\|ZP_04802809.1\| glycerol kinase [Thermoanaerobacter sp. X513], gi\|242230500\|gb\|EES32... GLPK_THEPX - Glycerol kinase OS=Thermoanaerobacter sp. (strain X514) GN=glpK PE=3 SV=1	506.0	[0..12]	[518..3]
gi\|7434247 - gi\|7434247\|pir\|\|C72254 glycerol kinase - Thermotoga maritima (strain MSB8) gi\|15644181, gi\|... - gi\|4981995\|gb\|AAD36500.1\|AE001795_3 glycerol kinase [Thermotoga maritima MSB8], gi\|15644181\|ref\|NP_2...	504.0	[0..12]	[504..2]
gi\|52426043, gi\|... - gi\|52426043\|ref\|YP_089180.1\| glycerol kinase [Mannheimia succiniciproducens MBEL55E], gi\|52308095\|gb...	504.0	[0..2]	[521..10]
GLPK_PSEPK - Glycerol kinase OS=Pseudomonas putida (strain KT2440) GN=glpK PE=3 SV=1	503.0	[0..5]	[518..1]
GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi GN=glpK PE=3 SV=1 GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=glpK PE=3 SV=1	501.0	[0..7]	[517..1]
GLPK_PSEP1 - Glycerol kinase OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=glpK PE=3 SV=1	501.0	[0..5]	[518..1]
gi\|115250422, gi... - gi\|126698985\|ref\|YP_001087882.1\| glycerol kinase [Clostridium difficile 630], gi\|115250422\|emb\|CAJ68...	501.0	[0..10]	[519..2]

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Predicted Domain #1

Region A:
Residues: [1-530]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARLFTLSES KYYLMALDAG TGSIRAVIFD LEGNQIAVGQ AEWRHLAVPD VPGSMEFDLN  60
   61 KNWQLACECM RQALHNAGIA PEYIAAVSAC SMREGIVLYN NEGAPIWACA NVDARAAREV 120
  121 SELKELHNNT FENEVYRATG QTLALSAIPR LLWLAHHRSD IYRQASTITM ISDWLAYMLS 180
  181 GELAVDPSNA GTTGLLDLTT RDWKPALLDM AGLRADILSP VKETGTLLGV VSSQAAELCG 240
  241 LKAGTPVVVG GGDVQLGCLG LGVVRPAQTA VLGGTFWQQV VNLAAPVTDP EMNVRVNPHV 300
  301 IPGMVQAESI SFFTGLTMRW FRDAFCAEEK LIAERLGIDT YTLLEEMASR VPPGSWGVMP 360
  361 IFSDRMRFKT WYHAAPSFIN LSIDPDKCNK ATLFRALEEN AAIVSACNLQ QIADFSNIHP 420
  421 SSLVFAGGGS KGKLWSQILA DVSGLPVNIP VVKEATALGC AIAAGVGAGI FSSMAETGER 480
  481 LVRWERTHTP DPEKHELYQD SRDKWQAVYQ DQLGLVDHGL TTSLWKAPGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	141.0
Match:	2p3rA
Description:	No description for 2p3rA was found.

Predicted functions:

Term	Confidence	Notes
glycerol kinase activity	2.81995993272027	bayes_pls_golite062009
carbohydrate kinase activity	2.33338276303563	bayes_pls_golite062009
hexokinase activity	1.70516840340504	bayes_pls_golite062009
binding	1.28018709416814	bayes_pls_golite062009
protein binding	0.856838411407636	bayes_pls_golite062009
glucokinase activity	0.47468456642723	bayes_pls_golite062009
kinase activity	0.460541310603011	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.381597272143844	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.324655711623803	bayes_pls_golite062009
glucose binding	0.31060748948812	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
transferase activity	0.105619024604158	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: