YRC Public Data Repository - Protein Structure Prediction

Protein:	YDCM_ECOLI
Organism:	Escherichia coli
Length:	402 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDCM_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|25325075 - pir\|\|G86117 probable virulence protein Z5816 [imported] - Escherichia coli (strain O157:H7, substrai... gi\|12519201, gi\|... - gi\|15804796\|ref\|NP_290837.1\| putative virulence protein [Escherichia coli O157:H7 EDL933], gi\|125192... gi\|38704244 - gi\|38704244\|ref\|NP_313210.2\| putative transposase [Escherichia coli O157:H7] gi\|38704244 - gi\|38704244\|ref\|NP_313210.2\| putative transposase [Escherichia coli O157:H7 str. Sakai] gi\|189369002, gi... - gi\|189403856\|ref\|ZP_02785457.2\| IS605 family transposase orfB [Escherichia coli O157:H7 str. EC4501]... gi\|217325334, gi... - gi\|217325334\|ref\|ZP_03441418.1\| transposase, IS605 orfB family [Escherichia coli O157:H7 str. TW1458...	322.0	[0..1]	[402..1]
gi\|81241947, gi\|... - gi\|82777799\|ref\|YP_404148.1\| putative virulence protein [Shigella dysenteriae Sd197], gi\|81241947\|gb...	321.0	[0..1]	[402..1]
gi\|74312216, gi\|... - gi\|74312216\|ref\|YP_310635.1\| putative virulence protein [Shigella sonnei Ss046], gi\|73855693\|gb\|AAZ8...	317.0	[0..1]	[402..1]
gi\|13364660 - gi\|13364660\|dbj\|BAB38606.1\| putative transposase TnpB of insertion sequence IS609 [Escherichia coli ... gi\|13364660 - gi\|13364660\|dbj\|BAB38606.1\| putative transposase TnpB of insertion sequence IS609 [Escherichia coli ... gi\|25325057 - pir\|\|G91276 hypothetical protein ECs5183 [imported] - Escherichia coli (strain O157:H7, substrain R...	305.0	[0..21]	[402..1]
gi\|75175208 - gi\|75175208\|ref\|ZP_00695524.1\| COG0675: Transposase and inactivated derivatives [Shigella boydii BS5...	304.0	[0..21]	[402..1]
gi\|75231809 - gi\|75231809\|ref\|ZP_00718150.1\| COG0675: Transposase and inactivated derivatives [Escherichia coli B7...	303.0	[0..21]	[402..1]
gi\|75190481 - gi\|75190481\|ref\|ZP_00703748.1\| COG0675: Transposase and inactivated derivatives [Escherichia coli E2...	303.0	[0..21]	[402..1]
gi\|75259549 - gi\|75259549\|ref\|ZP_00730868.1\| COG0675: Transposase and inactivated derivatives [Escherichia coli E2...	303.0	[0..21]	[402..1]

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Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRLQAFKFQ LRPGGQQECE MRRFAGACRF VFNRALARQN ENHEAGNKYI PYGKMASWLV  60
   61 EWKNATETQW LKDSPSQPLQ QSLKDLERAY KNFFRKRAAF PRFKKRGQN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.697	N/A	N/A	a.47.2	t-snare proteins
View	Download	0.681	N/A	N/A	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.630	N/A	N/A	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.623	N/A	N/A	a.7.6	Ribosomal protein S20
View	Download	0.618	N/A	N/A	a.7.3	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain

Predicted Domain #2

Region A:
Residues: [110-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAFRYPQGVK LDQENSRIFL PKLGWMRYRN SRQVTGVVKN VTVSQSCGKW YISIQTESEV  60
   61 STPVHPSASM VGLDAGVAKL ATLSDGTVFE PVNSFQKNQK KLARLQRQLS RKVKFSNNWQ 120
  121 KQKRKIQRLH SCIANIRRDY LHKVTTAVSK NHAMIVIEDL KVSNMSKSAA GTVSQPG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.618	N/A	N/A	b.55.1	PH domain-like
View	Download	0.560	N/A	N/A	d.19.1	MHC antigen-recognition domain
View	Download	0.527	N/A	N/A	b.1.10	Clathrin adaptor appendage domain
View	Download	0.513	N/A	N/A	b.1.16	Lamin A/C globular tail domain
View	Download	0.431	N/A	N/A	b.61.2	Metalloprotease inhibitor

Predicted Domain #3

Region A:
Residues: [287-402]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNVRAKSGLN RSILDQGWYE MRRQLAYKQL WRGGQVLAVP PAYTSQRCAY CGHTAKENRL  60
   61 SQSKFRCQVC GYTANADVNG ARNILAAGHA VLACGEMVQS GRPLKQEPTE MIQATA

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	32.69897
Match:	PF07282.2
Description:	No description for PF07282.2 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.731	N/A	N/A	c.20.1	Initiation factor IF2/eIF5b, domain 3
View	Download	0.362	N/A	N/A	c.44.2	Enzyme IIB-cellobiose
View	Download	0.360	N/A	N/A	c.30.1	PreATP-grasp domain
View	Download	0.355	N/A	N/A	d.93.1	SH2 domain
View	Download	0.252	N/A	N/A	d.134.1	Sulfite reductase hemoprotein (SiRHP), domains 2 and 4

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits