YRC Public Data Repository - Protein Structure Prediction

Protein:	YDCJ_ECOLI
Organism:	Escherichia coli
Length:	447 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDCJ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|24052123, gi\|... - gi\|24113139\|ref\|NP_707649.1\| hypothetical protein SF1787 [Shigella flexneri 2a str. 301], gi\|2405212... gi\|30041142, gi\|... - gi\|30062894\|ref\|NP_837065.1\| hypothetical protein S1487 [Shigella flexneri 2a str. 2457T], gi\|300411... gi\|110615278, gi... - gi\|110805730\|ref\|YP_689250.1\| hypothetical protein SFV_1782 [Shigella flexneri 5 str. 8401], gi\|1106...	625.0	[0..1]	[447..1]
gi\|194434286, gi... - gi\|83569228\|ref\|ZP_00920685.1\| COG5383: Uncharacterized protein conserved in bacteria [Shigella dyse...	625.0	[0..1]	[447..1]
gi\|193062723, gi... - gi\|75259541\|ref\|ZP_00730860.1\| COG5383: Uncharacterized protein conserved in bacteria [Escherichia c... gi\|218351695, gi... - gi\|218694963\|ref\|YP_002402630.1\| hypothetical protein EC55989_1553 [Escherichia coli 55989], gi\|2183...	624.0	[0..1]	[447..1]
gi\|75178629, gi\|... - gi\|75178629\|ref\|ZP_00698675.1\| COG5383: Uncharacterized protein conserved in bacteria [Shigella boyd...	624.0	[0..1]	[447..1]
gi\|81241164, gi\|... - gi\|82777016\|ref\|YP_403365.1\| hypothetical protein SDY_1757 [Shigella dysenteriae Sd197], gi\|81241164...	623.0	[0..1]	[447..1]
gi\|190904813, gi... - gi\|75231817\|ref\|ZP_00718158.1\| COG5383: Uncharacterized protein conserved in bacteria [Escherichia c...	623.0	[0..1]	[447..1]
gi\|157081197, gi... - gi\|75190472\|ref\|ZP_00703739.1\| COG5383: Uncharacterized protein conserved in bacteria [Escherichia c... gi\|209911955, gi... - gi\|209918696\|ref\|YP_002292780.1\| hypothetical protein ECSE_1505 [Escherichia coli SE11], gi\|20991195...	623.0	[0..1]	[447..1]
gi\|75242167, gi\|... - gi\|75242167\|ref\|ZP_00725961.1\| COG5383: Uncharacterized protein conserved in bacteria [Escherichia c...	621.0	[0..1]	[447..1]
gi\|110343198, gi... - gi\|110641606\|ref\|YP_669336.1\| putative cytoplasmic protein [Escherichia coli 536], gi\|110343198\|gb\|A...	621.0	[0..1]	[447..1]
gi\|209157592, gi... - gi\|209396192\|ref\|YP_002270433.1\| hypothetical protein ECH74115_2028 [Escherichia coli O157:H7 str. E... gi\|25356955 - pir\|\|D90882 hypothetical protein ECs2028 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|217329455, gi... - gi\|217329455\|ref\|ZP_03445535.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. TW1458... gi\|195938044 - gi\|195938044\|ref\|ZP_03083426.1\| hypothetical protein EscherichcoliO157_16692 [Escherichia coli O157:... gi\|208724530, gi... - gi\|208811024\|ref\|ZP_03252857.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4206... gi\|208732587, gi... - gi\|208815939\|ref\|ZP_03257118.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4045... gi\|208821332, gi... - gi\|208821332\|ref\|ZP_03261652.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4042... gi\|189366692, gi... - gi\|189366692\|gb\|EDU85108.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501], g... gi\|168777180, gi... - gi\|187767531\|gb\|EDU31375.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4196], g... gi\|168782916, gi... - gi\|188999674\|gb\|EDU68660.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4076], g... gi\|15831282, gi\|... - gi\|15831282\|ref\|NP_310055.1\| hypothetical protein ECs2028 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|168799696, gi... - gi\|189377917\|gb\|EDU96333.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC508], gi... gi\|188016632, gi... - gi\|188016632\|gb\|EDU54754.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4113], g... gi\|189356828, gi... - gi\|189356828\|gb\|EDU75247.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4401], g... gi\|15831282, gi\|... - gi\|15831282\|ref\|NP_310055.1\| hypothetical protein ECs2028 [Escherichia coli O157:H7], gi\|13361494\|db...	621.0	[0..1]	[447..1]

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Predicted Domain #1

Region A:
Residues: [1-172]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANSITADEI REQFSQAMSA MYQQEVPQYG TLLELVADVN LAVLENNPQL HEKMVNADEL  60
   61 ARLNVERHGA IRVGTAQELA TLRRMFAIMG MYPVSYYDLS QAGVPVHSTA FRPIDDASLA 120
  121 RNPFRVFTSL LRLELIENEI LRQKAAEILR QRDIFTPRCR QLLEEYEQQG GF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.780	N/A	N/A	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.647	N/A	N/A	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.562	N/A	N/A	a.130.1	Chorismate mutase II
View	Download	0.544	N/A	N/A	a.1.1	Globin-like
View	Download	0.516	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain

Predicted Domain #2

Region A:
Residues: [173-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NETQAQEFVQ EALETFRWHQ SATVDEETYR ALHNEHRLIA DVVCFPGCHI NHLTPRTLDI  60
   61 DRVQSMMPEC GIEPKILIEG PPRREVPILL RQTSFKALEE TVLFAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.69897
Match:	1jc4A
Description:	Methylmalonyl-CoA epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.451352729218579	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [279-447]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKQGTHTARF GEIEQRGVAL TPKGRQLYDD LLRNAGTGQD NLTHQMHLQE TFRTFPDSEF  60
   61 LMRQQGLAWF RYRLTPSGEA HRQAIHPGDD PQPLIERGWV VAQPITYEDF LPVSAAGIFQ 120
  121 SNLGNETQTR SHGNASREAF EQALGCPVLD EFQLYQEAEE RSKRRCGLL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.235	N/A	N/A	a.3.1	Cytochrome c
View	Download	0.208	N/A	N/A	a.23.2	Diol dehydratase, gamma subunit

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: