YRC Public Data Repository - Protein Structure Prediction

Protein:	YCGV_ECOLI
Organism:	Escherichia coli
Length:	955 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCGV_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194415965, gi... - gi\|75212640\|ref\|ZP_00712638.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	289.0	[0..1]	[955..1]
gi\|75511762, gi\|... - gi\|75511762\|ref\|ZP_00734391.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	288.0	[0..1]	[955..1]
gi\|192955508, gi... - gi\|75233901\|ref\|ZP_00718361.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	288.0	[0..1]	[955..1]
gi\|24051505, gi\|... - gi\|24112601\|ref\|NP_707111.1\| putative adhesion and penetration protein [Shigella flexneri 2a str. 30... gi\|30040974, gi\|... - gi\|30062726\|ref\|NP_836897.1\| putative adhesion and penetration protein [Shigella flexneri 2a str. 24...	288.0	[0..1]	[955..1]
gi\|110805207, gi... - gi\|110805207\|ref\|YP_688727.1\| putative adhesion and penetration protein [Shigella flexneri 5 str. 84...	285.0	[0..1]	[955..1]
gi\|75228264, gi\|... - gi\|75228264\|ref\|ZP_00714919.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	279.0	[0..1]	[955..1]
gi\|157157255, gi... - gi\|75190256\|ref\|ZP_00703523.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	279.0	[0..1]	[955..1]
tr\|A0A0G3HVN8\|A0... - Putative adhesin protein OS=Escherichia coli (strain K12) GN=ycgV PE=4 SV=1 gi\|83587346 - gi\|83587346\|ref\|ZP_00925974.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	266.0	[0..81]	[955..2]
gi\|75195355 - gi\|75195355\|ref\|ZP_00705425.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	266.0	[0..81]	[955..2]
gi\|75255350 - gi\|75255350\|ref\|ZP_00727170.1\| COG3210: Large exoproteins involved in heme utilization or adhesion [...	258.0	[0..30]	[897..3]

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Predicted Domain #1

Region A:
Residues: [1-643]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIKQHNGNT KADRLAELKI RSPSIQLIKF GAIGLNAIIF SPLLIAADTG SQYGTNITIN  60
   61 DGDRITGDTA DPSGNLYGVM TPAGNTPGNI NLGNDVTVNV NDASGYAKGI IIQGKNSSLT 120
  121 ANRLTVDVVG QTSAIGINLI GDYTHADLGT GSTIKSNDDG IIIGHSSTLT ATQFTIENSN 180
  181 GIGLTINDYG TSVDLGSGSK ITTDGSTGVY IGGLNGNNAN GAARFTATDL TIDVQGYSAM 240
  241 GINVQKNSVV DLGTNSTIKT NGDNAHGLWS FGQVSANALT VDVTGAAANG VEVRGGTTTI 300
  301 GADSHISSAQ GGGLVTSGSD AIINFTGTAA QRNSIFSGGS YGASAQTATA VVNMQNTDIT 360
  361 VDRNGSLALG LWALSGGRIT GDSLAITGAA GARGIYAMTN SQIDLTSDLV IDMSTPDQMA 420
  421 IATQHDDGYA ASRINASGRM LINGSVLSKG GLINLDMHPG SVWTGSSLSD NVNGGKLDVA 480
  481 MNNSVWNVTS NSNLDTLALS HSTVDFASHG STAGTFATLN VENLSGNSTF IMRADVVGEG 540
  541 NGVNNKGDLL NISGSSAGNH VLAIRNQGSE ATTGNEVLTV VKTTDGAASF SASSQVELGG 600
  601 YLYDVRKNGT NWELYASGTV PEPTPNPEPT PAPAQPPIVN PDP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.45
Match:	1dabA
Description:	Virulence factor P.69 pertactin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.117240936500135	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [644-955]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPEPAPTPKP TTTADAGGNY LNVGYLLNYV ENRTLMQRMG DLRNQSKDGN IWLRSYGGSL  60
   61 DSFASGKLSG FDMGYSGIQF GGDKRLSDVM PLYVGLYIGS THASPDYSGG DGTARSDYMG 120
  121 MYASYMAQNG FYSDLVIKAS RQKNSFHVLD SQNNGVNANG TANGMSISLE AGQRFNLSPT 180
  181 GYGFYIEPQT QLTYSHQNEM TMKASNGLNI HLNHYESLLG RASMILGYDI TAGNSQLNVY 240
  241 VKTGAIREFS GDTEYLLNNS REKYSFKGNG WNNGVGVSAQ YNKQHTFYLE ADYTQGNLFD 300
  301 QKQVNGGYRF SF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.045757
Match:	1uynX
Description:	Translocator domain of autotransporter NalP from Neisseria meningitidis
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: