YRC Public Data Repository - Protein Structure Prediction

Protein:	PGAA_ECOLI, YCDS...
Organism:	Escherichia coli
Length:	807 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGAA_ECOLI, YCDS....

Description	E-value	Query Range	Subject Range
gi\|12514389, gi\|... - gi\|15801015\|ref\|NP_287031.1\| outer membrane protein PgaA [Escherichia coli O157:H7 EDL933], gi\|12514... gi\|25340116 - gi\|25340116\|pir\|\|F85647 probable outer membrane protein ycdS [imported] - Escherichia coli (strain O...	418.0	[0..1]	[807..1]
gi\|190907302, gi... - gi\|191172418\|ref\|ZP_03033959.1\| biofilm PGA synthesis protein PgaA [Escherichia coli F11], gi\|190907... gi\|110641207, gi... - gi\|110641207\|ref\|YP_668937.1\| outer membrane protein PgaA [Escherichia coli 536], gi\|110342799\|gb\|AB...	417.0	[0..1]	[807..1]
gi\|227884020, gi... - gi\|227884020\|ref\|ZP_04001825.1\| outer membrane protein PgaA [Escherichia coli 83972], gi\|227838772\|g... gi\|226898200, gi... - gi\|237706990\|ref\|ZP_04537471.1\| outer membrane protein PgaA [Escherichia sp. 3_2_53FAA], gi\|22689820... gi\|26247048, gi\|... - gi\|26247048\|ref\|NP_753088.1\| outer membrane protein PgaA [Escherichia coli CFT073], gi\|26107448\|gb\|A... gi\|91071690, gi\|... - gi\|91210116\|ref\|YP_540102.1\| outer membrane protein PgaA [Escherichia coli UTI89], gi\|91071690\|gb\|AB...	411.0	[0..1]	[807..1]
gi\|117623219, gi... - gi\|117623219\|ref\|YP_852132.1\| outer membrane protein PgaA [Escherichia coli APEC O1], gi\|115512343\|g...	410.0	[0..1]	[807..1]
gi\|75234344 - gi\|75234344\|ref\|ZP_00718714.1\| COG0457: FOG: TPR repeat [Escherichia coli E110019]	410.0	[0..42]	[807..2]
gi\|75513473 - gi\|75513473\|ref\|ZP_00735877.1\| COG0457: FOG: TPR repeat [Escherichia coli 53638] gi\|75210303 - gi\|75210303\|ref\|ZP_00710465.1\| COG0457: FOG: TPR repeat [Escherichia coli B171] gi\|83586433 - gi\|83586433\|ref\|ZP_00925067.1\| COG0457: FOG: TPR repeat [Escherichia coli 101-1]	409.0	[0..42]	[807..2]
gi\|75240630 - gi\|75240630\|ref\|ZP_00724547.1\| COG0457: FOG: TPR repeat [Escherichia coli F11]	408.0	[0..42]	[807..2]
gi\|75257466 - gi\|75257466\|ref\|ZP_00728969.1\| COG0457: FOG: TPR repeat [Escherichia coli E22]	408.0	[0..42]	[807..2]
gi\|75190087 - gi\|75190087\|ref\|ZP_00703354.1\| COG0457: FOG: TPR repeat [Escherichia coli E24377A]	406.0	[0..38]	[807..23]
gi\|45436370, gi\|... - gi\|45441509\|ref\|NP_993048.1\| outer membrane protein PgaA [Yersinia pestis biovar Microtus str. 91001...	376.0	[0..1]	[807..22]

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Predicted Domain #1

Region A:
Residues: [1-64]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSSSRKRCP KTKWALKLLT AAFLAASPAA KSAVNNAYDA LIIEARKGNT QPALSWFALK  60
   61 SALS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [65-580]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNQIADWLQI ALWAGQDKQV ITVYNRYRHQ QLPARGYAAV AVAYRNLQQW QNSLTLWQKA  60
   61 LSLEPQNKDY QRGQILTLAD AGHYDTALVK LKQLNSGAPD KANLLAEAYI YKLAGRHQDE 120
  121 LRAMTESLPE NASTQQYPTE YVQALRNNQL AAAIDDANLT PDIRADIHAE LVRLSFMPTR 180
  181 SESERYAIAD RALAQYAALE ILWHDNPDRT AQYQRIQVDH LGALLTRDRY KDVISHYQRL 240
  241 KKTGQIIPPW GQYWVASAYL KDHQPKKAQS IMTELFYHKE TIAPDLSDEE LADLFYSHLE 300
  301 SENYPGALTV TQHTINTSPP FLRLMGTPTS IPNDTWLQGH SFLSTVAKYS NDLPQAEMTA 360
  361 RELAYNAPGN QGLRIDYASV LQARGWPRAA ENELKKAEVI EPRNINLEVE QAWTALTLQE 420
  421 WQQAAVLTHD VVEREPQDPG VVRLKRAVDV HNLAELRIAG STGIDAEGPD SGKHDVDLTT 480
  481 IVYSPPLKDN WRGFAGFGYA DGQFSEGKGI VRDWLA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.221849
Match:	2gw1A
Description:	No description for 2gw1A was found.

Predicted Domain #3

Region A:
Residues: [581-641]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVEWRSRNIW LEAEYAERVF NHEHKPGARL SGWYDFNDNW RIGSQLERLS HRVPLRAMKN  60
   61 G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.69897
Match:	1hz4A
Description:	Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.929905657301058	bayes_pls_golite062009
protein binding	0.590437877414495	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [642-807]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTGNSAQAYV RWYQNERRKY GVSWAFTDFS DSNQRHEVSL EGQERIWSSP YLIVDFLPSL  60
   61 YYEQNTEHDT PYYNPIKTFD IVPAFEASHL LWRSYENSWE QIFSAGVGAS WQKHYGTDVV 120
  121 TQLGYGQRIS WNDVIDAGAT LRWEKRPYDG DREHNLYVEF DMTFRF

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.24
Match:	2jmmA
Description:	No description for 2jmmA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: