YRC Public Data Repository - Protein Structure Prediction

Protein:	YCDO_ECOLI
Organism:	Escherichia coli
Length:	375 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCDO_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194413527, gi... - gi\|75210296\|ref\|ZP_00710458.1\| COG2822: Predicted periplasmic lipoprotein involved in iron transport...	438.0	[0..1]	[375..1]
gi\|22126334, gi\|... - gi\|22126334\|ref\|NP_669757.1\| hypothetical protein y2451 [Yersinia pestis KIM], gi\|21959315\|gb\|AAM860... gi\|45436217, gi\|... - gi\|45441357\|ref\|NP_992896.1\| hypothetical protein YP_1538 [Yersinia pestis biovar Microtus str. 9100...	438.0	[0..5]	[375..14]
gi\|75190081, gi\|... - gi\|75190081\|ref\|ZP_00703348.1\| COG2822: Predicted periplasmic lipoprotein involved in iron transport...	437.0	[0..1]	[375..1]
gi\|153947462, gi... - gi\|77628923\|ref\|ZP_00791509.1\| COG2822: Predicted periplasmic lipoprotein involved in iron transport...	437.0	[0..5]	[375..6]
gi\|218364676, gi... - gi\|218557907\|ref\|YP_002390820.1\| hypothetical protein ECS88_1034 [Escherichia coli S88], gi\|21836467... EFEO_ECOK1 - Iron uptake system component EfeO OS=Escherichia coli O1:K1 / APEC GN=efeO PE=3 SV=1 gi\|75240624, gi\|... - gi\|75240624\|ref\|ZP_00724541.1\| COG2822: Predicted periplasmic lipoprotein involved in iron transport... EFEO_ECOUT - Iron uptake system component EfeO OS=Escherichia coli (strain UTI89 / UPEC) GN=efeO PE=3 SV=1 gi\|226898207, gi... - gi\|237706997\|ref\|ZP_04537478.1\| ycdO [Escherichia sp. 3_2_53FAA], gi\|226898207\|gb\|EEH84466.1\| ycdO [...	436.0	[0..1]	[375..1]
gi\|218351285, gi... - gi\|218694553\|ref\|YP_002402220.1\| hypothetical protein EC55989_1128 [Escherichia coli 55989], gi\|2183... gi\|192927827, gi... - gi\|75257460\|ref\|ZP_00728963.1\| COG2822: Predicted periplasmic lipoprotein involved in iron transport...	436.0	[0..1]	[375..1]
EFEO_ECOL6 - Iron uptake system component EfeO OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=... YCDO_ECOL6 - UPF0409 protein ycdO OS=Escherichia coli O6 GN=ycdO PE=2 SV=1 gi\|227838779, gi... - gi\|227884027\|ref\|ZP_04001832.1\| PbrT family lead (Pb2+) uptake porter [Escherichia coli 83972], gi\|2...	436.0	[0..1]	[375..1]
gi\|75513467, gi\|... - gi\|75513467\|ref\|ZP_00735871.1\| COG2822: Predicted periplasmic lipoprotein involved in iron transport...	436.0	[0..1]	[375..1]
gi\|189372776, gi... - gi\|189372776\|gb\|EDU91192.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC869], gi... gi\|168781041, gi... - gi\|189001280\|gb\|EDU70266.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4076], g... gi\|187770496, gi... - gi\|187770496\|gb\|EDU34340.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4196], g... gi\|189363053, gi... - gi\|189363053\|gb\|EDU81472.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4486], g... gi\|15830518, gi\|... - gi\|15830518\|ref\|NP_309291.1\| hypothetical protein ECs1264 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|208732586, gi... - gi\|208815938\|ref\|ZP_03257117.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4045... gi\|208725487, gi... - gi\|208805686\|ref\|ZP_03248023.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4206... gi\|195935276 - gi\|195935276\|ref\|ZP_03080658.1\| hypothetical protein EscherichcoliO157_02277 [Escherichia coli O157:... gi\|168799148, gi... - gi\|189378252\|gb\|EDU96668.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC508], gi... EFEO_ECO57 - Iron uptake system component EfeO OS=Escherichia coli O157:H7 GN=efeO PE=1 SV=1 gi\|189368802, gi... - gi\|189368802\|gb\|EDU87218.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501], g... gi\|209773890, gi... - pir\|\|H85646 hypothetical protein ycdO [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|168754345, gi... - gi\|189358149\|gb\|EDU76568.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4401], g... gi\|168747359, gi... - gi\|188018041\|gb\|EDU56163.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4113], g... gi\|12514380, gi\|... - gi\|15801009\|ref\|NP_287025.1\| hypothetical protein Z1520 [Escherichia coli O157:H7 EDL933], gi\|125143... gi\|254792276, gi... - gi\|254792276\|ref\|YP_003077113.1\| component of a tripartite ferrous iron transporter [Escherichia col... gi\|217318743, gi... - gi\|217328316\|ref\|ZP_03444398.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. TW1458... gi\|209399390, gi... - gi\|209399390\|ref\|YP_002269744.1\| hypothetical protein ECH74115_1259 [Escherichia coli O157:H7 str. E... gi\|208737504, gi... - gi\|208822019\|ref\|ZP_03262338.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4042...	436.0	[0..1]	[375..1]
EFEO_ECOL5 - Iron uptake system component EfeO OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=efeO PE=3 SV...	434.0	[0..1]	[375..1]

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Predicted Domain #1

Region A:
Residues: [1-120]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTINFRRNAL QLSVAALFSS AFMANAADVP QVKVTVTDKQ CEPMTITVNA GKTQFIIQNH  60
   61 SQKALEWEIL KGVMVVEERE NIAPGFSQKM TANLQPGEYD MTCGLLTNPK GKLIVKGEAT 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.95
Match:	1id2A
Description:	Amicyanin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cation transmembrane transporter activity	2.76760395701129	bayes_pls_golite062009
ion transmembrane transporter activity	2.71776476059735	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.47457164800953	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.37085675246767	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.97742135944175	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.34694403527701	bayes_pls_golite062009
iron ion transmembrane transporter activity	1.33830105950462	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.15849170179095	bayes_pls_golite062009
transporter activity	1.07068062043283	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.04695981379478	bayes_pls_golite062009
transmembrane transporter activity	0.945328688400573	bayes_pls_golite062009
substrate-specific transporter activity	0.676868199441525	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.591685560349053	bayes_pls_golite062009
copper ion binding	0.427568187641398	bayes_pls_golite062009
ferroxidase activity	0.0511841475612584	bayes_pls_golite062009
oxidoreductase activity, oxidizing metal ions, oxygen as acceptor	0.0511841475612584	bayes_pls_golite062009
binding	0.00959244302248818	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [121-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADAAQSDALL SLGGAITAYK AYVMAETTQL VTDTKAFTDA IKAGDIEKAK ALYAPTRQHY  60
   61 ERIEPIAELF SDLDGSIDAR EDDYEQKAAD PKFTGFHRLE KALFGDNTTK GMDQYAEQLY 120
  121 TDVVDLQKRI SELAFPPSKV VGGAAGLIEE VAASKISGEE DRYSH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [286-375]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDLWDFQANV EGSQKIVDLL RPQLQKANPE LLAKVDANFK KVDTILAKYR TKDGFETYDK  60
   61 LTDADRNALK GPITALAEDL AQLRGVLGLD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: