YRC Public Data Repository - Protein Structure Prediction

Protein:	YBIP_ECOLI
Organism:	Escherichia coli
Length:	527 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBIP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71558621, gi\|... - gi\|71738068\|ref\|YP_273798.1\| hypothetical protein PSPPH_1546 [Pseudomonas syringae pv. phaseolicola ...	293.0	[0..3]	[504..12]
gi\|81240254, gi\|... - gi\|82776106\|ref\|YP_402453.1\| putative enzyme [Shigella dysenteriae Sd197], gi\|81240254\|gb\|ABB60964.1...	289.0	[0..1]	[527..1]
gi\|110342611, gi... - gi\|110641019\|ref\|YP_668747.1\| putative membrane protein YbiP [Escherichia coli 536], gi\|110342611\|gb... gi\|75238150, gi\|... - gi\|75238150\|ref\|ZP_00722154.1\| COG2194: Predicted membrane-associated, metal-dependent hydrolase [Es... gi\|26107190, gi\|... - gi\|26246791\|ref\|NP_752831.1\| hypothetical protein c0901 [Escherichia coli CFT073], gi\|26107190\|gb\|AA... gi\|227838973, gi... - gi\|227884221\|ref\|ZP_04002026.1\| sulfatase family protein [Escherichia coli 83972], gi\|227838973\|gb\|E...	289.0	[0..1]	[527..1]
gi\|30062299, gi\|... - gi\|30062299\|ref\|NP_836470.1\| putative enzyme [Shigella flexneri 2a str. 2457T], gi\|30040544\|gb\|AAP16... gi\|24051023, gi\|... - gi\|24112183\|ref\|NP_706693.1\| putative enzyme [Shigella flexneri 2a str. 301], gi\|24051023\|gb\|AAN4240... gi\|110804815, gi... - gi\|110804815\|ref\|YP_688335.1\| putative enzyme [Shigella flexneri 5 str. 8401], gi\|110614363\|gb\|ABF03...	289.0	[0..1]	[527..1]
gi\|157154892, gi... - gi\|75189856\|ref\|ZP_00703123.1\| COG2194: Predicted membrane-associated, metal-dependent hydrolase [Es...	288.0	[0..1]	[527..1]
gi\|209160080, gi... - gi\|209398680\|ref\|YP_002269485.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4115], gi... gi\|208822764, gi... - gi\|208822764\|ref\|ZP_03263083.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4042], gi\|... gi\|209775750, gi... - pir\|\|E90740 probable enzyme [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952), ... gi\|208732873, gi... - gi\|208816225\|ref\|ZP_03257404.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|13360352, gi\|... - gi\|15830147\|ref\|NP_308920.1\| hypothetical protein ECs0893 [Escherichia coli O157:H7], gi\|13360352\|db... gi\|195936856 - gi\|195936856\|ref\|ZP_03082238.1\| hypothetical protein EscherichcoliO157_10390 [Escherichia coli O157:... gi\|254792011, gi... - gi\|254792011\|ref\|YP_003076848.1\| predicted hydrolase, inner membrane [Escherichia coli O157:H7 str. ... gi\|217321901, gi... - gi\|217325680\|ref\|ZP_03441764.1\| sulfatase family protein [Escherichia coli O157:H7 str. TW14588], gi... gi\|13360352, gi\|... - gi\|15830147\|ref\|NP_308920.1\| hypothetical protein ECs0893 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|189363581, gi... - gi\|189363581\|gb\|EDU82000.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|168763338, gi... - gi\|189366499\|gb\|EDU84915.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4501], gi\|1687... gi\|168756606, gi... - gi\|189356306\|gb\|EDU74725.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4401], gi\|1687... gi\|168749996, gi... - gi\|188015743\|gb\|EDU53865.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|168799906, gi... - gi\|189377750\|gb\|EDU96166.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC508], gi\|16879... gi\|189373073, gi... - gi\|189373073\|gb\|EDU91489.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|168779364, gi... - gi\|189002858\|gb\|EDU71844.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|187768251, gi... - gi\|187768251\|gb\|EDU32095.1\| sulfatase family protein [Escherichia coli O157:H7 str. EC4196], gi\|1687...	287.0	[0..1]	[527..1]
tr\|Q87Y80\|Q87Y80... - Membrane protein, putative OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_3923 PE=4 SV=... gi\|28871075, gi\|... - gi\|28871075\|ref\|NP_793694.1\| hypothetical protein PSPTO_3923 [Pseudomonas syringae pv. tomato str. D...	287.0	[0..3]	[504..12]
gi\|115512120, gi... - gi\|117622996\|ref\|YP_851909.1\| hypothetical protein APECO1_1276 [Escherichia coli APEC O1], gi\|115512... gi\|237707223, gi... - gi\|237707223\|ref\|ZP_04537704.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|218364489, gi... - gi\|218557720\|ref\|YP_002390633.1\| putative enzyme, UPF0141 family, inner membrane [Escherichia coli S... gi\|91209850, gi\|... - gi\|91209850\|ref\|YP_539836.1\| hypothetical protein UTI89_C0819 [Escherichia coli UTI89], gi\|91071424\|...	287.0	[0..1]	[527..1]
gi\|193069361, gi... - gi\|75236127\|ref\|ZP_00720251.1\| COG2194: Predicted membrane-associated, metal-dependent hydrolase [Es...	286.0	[0..1]	[527..1]
gi\|193064427, gi... - gi\|75257587\|ref\|ZP_00729084.1\| COG2194: Predicted membrane-associated, metal-dependent hydrolase [Es... gi\|194413805, gi... - gi\|75210590\|ref\|ZP_00710738.1\| COG2194: Predicted membrane-associated, metal-dependent hydrolase [Es... gi\|218351021, gi... - gi\|218694289\|ref\|YP_002401956.1\| putative enzyme, UPF0141 family, inner membrane [Escherichia coli 5...	285.0	[0..1]	[527..1]

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Predicted Domain #1

Region A:
Residues: [1-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLTLKESLV TRSRVFSPWT AFYFLQSLLI NLGLGYPFSL LYTAAFTAIL LLLWRTLPRV  60
   61 QKVLVGVSSL VAACYFPFAQ AYGAPNFNTL LALHSTNMEE STEILTIFPW YSYLVGLFIF 120
  121 ALGVIAIRRK KENEKARWNT FDSLCLVFSV ATFFVAPVQN LAWGGVFKLK DTGYPVFRFA 180
  181 KDVIVNNNEV IEEQERMAKL SGMKDTWTVT AVK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [214-527]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKYQTYVVVI GESARRDALG AFGGHWDNTP FASSVNGLIF ADYIAASGST QKSLGLTLNR  60
   61 VVDGKPQFQD NFVTLANRAG FQTWWFSNQG QIGEYDTAIA SIAKRADEVY FLKEGNFEAD 120
  121 KNTKDEALLD MTAQVLAQEH SQPQLIVLHL MGSHPQACDR TQGKYETFVQ SKETSCYLYT 180
  181 MTQTDDLLRK LYDQLRNSGS SFSLVYFSDH GLAFKERGKD VQYLAHDDKY QQNFQVPFMV 240
  241 ISSDDKAHRV IKARRSANDF LGFFSQWTGI KAKEINIKYP FISEKKAGPI YITNFQLQKV 300
  301 DYNHLGTDIF DPKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.09691
Match:	1e3cP
Description:	Arylsulfatase A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.78323101437723	bayes_pls_golite062009
hydrolase activity	1.33940320180164	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.17808563980987	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: