YRC Public Data Repository - Protein Structure Prediction

Protein:	WCAK_ECOLI
Organism:	Escherichia coli
Length:	426 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WCAK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|83571251, gi\|... - gi\|83571251\|ref\|ZP_00922692.1\| COG2327: Uncharacterized conserved protein [Shigella dysenteriae 1012...	265.0	[0..1]	[426..1]
gi\|75177165, gi\|... - gi\|75177165\|ref\|ZP_00697263.1\| COG2327: Uncharacterized conserved protein [Shigella boydii BS512], g...	263.0	[0..1]	[426..1]
gi\|81244834, gi\|... - gi\|82543423\|ref\|YP_407370.1\| putative pyruvyl transferase [Shigella boydii Sb227], gi\|81244834\|gb\|AB...	263.0	[0..1]	[426..1]
gi\|75229103, gi\|... - gi\|75229103\|ref\|ZP_00715678.1\| COG2327: Uncharacterized conserved protein [Escherichia coli B7A], gi...	262.0	[0..1]	[426..1]
gi\|242377697, gi... - gi\|251785424\|ref\|YP_002999728.1\| hypothetical protein B21_01940 [Escherichia coli BL21], gi\|24237769... gi\|115513365, gi... - gi\|117624241\|ref\|YP_853154.1\| putative pyruvyl transferase [Escherichia coli APEC O1], gi\|115513365\|... gi\|253324067, gi... - gi\|254288825\|ref\|YP_003054573.1\| predicted pyruvyl transferase [Escherichia coli BL21(DE3)], gi\|2539... gi\|254162037, gi... - gi\|254162037\|ref\|YP_003045145.1\| predicted pyruvyl transferase [Escherichia coli B str. REL606], gi\|... gi\|237704500, gi... - gi\|237704500\|ref\|ZP_04534981.1\| colanic acid biosynthesis protein [Escherichia sp. 3_2_53FAA], gi\|22...	262.0	[0..1]	[426..1]
gi\|3041816 - gi\|3041816\|gb\|AAC77850.1\| unknown [Escherichia coli]	261.0	[0..1]	[426..1]
gi\|217329659, gi... - gi\|217329659\|ref\|ZP_03445738.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str... gi\|15832104, gi\|... - gi\|15832104\|ref\|NP_310877.1\| putative galactokinase [Escherichia coli O157:H7], gi\|13362318\|dbj\|BAB3... gi\|209160306, gi... - gi\|209398906\|ref\|YP_002271287.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 st... gi\|209748130, gi... - pir\|\|E85830 galactokinase (EC 2.7.1.6), probable wcaK [imported] - Escherichia coli (strain O157:H7,... gi\|208740672, gi... - gi\|208820549\|ref\|ZP_03260869.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str... gi\|12516236, gi\|... - gi\|15802525\|ref\|NP_288551.1\| putative pyruvyl transferase [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|168782329, gi... - gi\|189000086\|gb\|EDU69072.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC... gi\|187768946, gi... - gi\|187768946\|gb\|EDU32790.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC... gi\|189361251, gi... - gi\|189361251\|gb\|EDU79670.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC... gi\|168761787, gi... - gi\|189367756\|gb\|EDU86172.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC... gi\|15832104, gi\|... - gi\|15832104\|ref\|NP_310877.1\| putative pyruvyl transferase [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|208730849, gi... - gi\|208817230\|ref\|ZP_03258322.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str... gi\|254593229, gi... - gi\|254793829\|ref\|YP_003078666.1\| predicted pyruvyl transferase [Escherichia coli O157:H7 str. TW1435... gi\|208729274, gi... - gi\|208809473\|ref\|ZP_03251810.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str... gi\|195938238 - gi\|195938238\|ref\|ZP_03083620.1\| putative pyruvyl transferase [Escherichia coli O157:H7 str. EC4024] gi\|189378376, gi... - gi\|189378376\|gb\|EDU96792.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC... gi\|189355470, gi... - gi\|189355470\|gb\|EDU73889.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC... gi\|188015383, gi... - gi\|188015383\|gb\|EDU53505.1\| colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC...	261.0	[0..1]	[426..1]
gi\|157156059, gi... - gi\|75186843\|ref\|ZP_00700110.1\| COG2327: Uncharacterized conserved protein [Escherichia coli E24377A]...	261.0	[0..1]	[426..1]
gi\|75514075, gi\|... - gi\|75514075\|ref\|ZP_00736405.1\| COG2327: Uncharacterized conserved protein [Escherichia coli 53638], ...	261.0	[0..1]	[426..1]
gi\|91072904, gi\|... - gi\|91211330\|ref\|YP_541316.1\| putative pyruvyl transferase [Escherichia coli UTI89], gi\|91072904\|gb\|A...	260.0	[0..1]	[426..1]

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Predicted Domain #1

Region A:
Residues: [1-426]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLILGNHT CGNRGDSAIL RGLLDAINIL NPHAEVDVMS RYPVSSSWLL NRPVMGDPLF  60
   61 LQMKQHNSAA GVVGRVKKVL RRRYQHQVLL SRVTDTGKLR NIAIAQGFTD FVRLLSGYDA 120
  121 IIQVGGSFFV DLYGVPQFEH ALCTFMAKKP LFMIGHSVGP FQDEQFNQLA NYVFGHCDAL 180
  181 ILRESVSFDL MKRSNITTAK VEHGVDTAWL VDHHTEDFTA SYAVQHWLDV AAQQKTVAIT 240
  241 LRELAPFDKR LGTTQQAYEK AFAGVVNRIL DEGYQVIALS TCTGIDSYNK DDRMVALNLR 300
  301 QHISDPARYH VVMDELNDLE MGKILGACEL TVGTRLHSAI ISMNFATPAI AINYEHKSAG 360
  361 IMQQLGLPEM AIDIRHLLDG SLQAMVADTL GQLPALNARL SEAVSRERQT GMQMVQSVLE 420
  421 RIGEVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.522879
Match:	1pswA
Description:	ADP-heptose LPS heptosyltransferase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.12142599404571	bayes_pls_golite062009
transferase activity	1.04894606863363	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.929172049566779	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	0.18186445930239	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: