YRC Public Data Repository - Protein Structure Prediction

Protein:	UVRA_ECOLI
Organism:	Escherichia coli
Length:	940 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UVRA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75428562, gi\|... - gi\|75428562\|ref\|ZP_00731764.1\| excinuclease ATPase subunit [Actinobacillus succinogenes 130Z], gi\|74...	701.0	[0..1]	[940..1]
gi\|59479049, gi\|... - gi\|59710948\|ref\|YP_203724.1\| excinuclease ABC subunit A [Vibrio fischeri ES114], gi\|59479049\|gb\|AAW8...	700.0	[0..1]	[940..1]
gi\|77996706, gi\|... - gi\|78044591\|ref\|YP_359131.1\| excinuclease ABC, A subunit [Carboxydothermus hydrogenoformans Z-2901],...	696.0	[0..1]	[940..1]
gi\|89082277, gi\|... - gi\|89093587\|ref\|ZP_01166535.1\| excinuclease ABC subunit A [Oceanospirillum sp. MED92], gi\|89082277\|g...	696.0	[0..1]	[940..1]
gi\|90438441, gi\|... - gi\|90580139\|ref\|ZP_01235946.1\| excinuclease ABC subunit A [Vibrio angustum S14], gi\|90438441\|gb\|EAS6...	694.0	[0..1]	[940..1]
gi\|114771960 - gi\|114771960\|ref\|ZP_01449349.1\| excinuclease ABC subunit A [alpha proteobacterium HTCC2255] gi\|221134084 - gi\|221134084\|ref\|ZP_03560389.1\| excinuclease ABC subunit A [Glaciecola sp. HTCC2999] gi\|114771960, gi... - gi\|114771960\|ref\|ZP_01449349.1\| excinuclease ABC subunit A [alpha proteobacterium HTCC2255], gi\|1145...	692.0	[0..1]	[940..1]
gi\|95108771 - gi\|95108771\|emb\|CAK13465.1\| DNA excision repair enzyme subunit, with UvrBC [Pseudomonas entomophila ... gi\|95108771, gi\|... - gi\|95108771\|emb\|CAK13465.1\| DNA excision repair enzyme subunit, with UvrBC [Pseudomonas entomophila ...	692.0	[0..1]	[940..1]
UVRA_VIBVY - UvrABC system protein A OS=Vibrio vulnificus (strain YJ016) GN=uvrA PE=3 SV=2	691.0	[0..1]	[940..1]
gi\|89075307, gi\|... - gi\|89075307\|ref\|ZP_01161734.1\| excinuclease ABC subunit A [Photobacterium sp. SKA34], gi\|89048988\|gb...	691.0	[0..1]	[940..1]
UVRA_HAEIN - UvrABC system protein A OS=Haemophilus influenzae GN=uvrA PE=3 SV=1 UVRA_HAEIN - UvrABC system protein A OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=uvr...	691.0	[0..1]	[940..1]

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Predicted Domain #1

Region A:
Residues: [1-594]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKIEVRGAR THNLKNINLV IPRDKLIVVT GLSGSGKSSL AFDTLYAEGQ RRYVESLSAY  60
   61 ARQFLSLMEK PDVDHIEGLS PAISIEQKST SHNPRSTVGT ITEIHDYLRL LFARVGEPRC 120
  121 PDHDVPLAAQ TVSQMVDNVL SQPEGKRLML LAPIIKERKG EHTKTLENLA SQGYIRARID 180
  181 GEVCDLSDPP KLELQKKHTI EVVVDRFKVR DDLTQRLAES FETALELSGG TAVVADMDDP 240
  241 KAEELLFSAN FACPICGYSM RELEPRLFSF NNPAGACPTC DGLGVQQYFD PDRVIQNPEL 300
  301 SLAGGAIRGW DRRNFYYFQM LKSLADHYKF DVEAPWGSLS ANVHKVVLYG SGKENIEFKY 360
  361 MNDRGDTSIR RHPFEGVLHN MERRYKETES SAVREELAKF ISNRPCASCE GTRLRREARH 420
  421 VYVENTPLPA ISDMSIGHAM EFFNNLKLAG QRAKIAEKIL KEIGDRLKFL VNVGLNYLTL 480
  481 SRSAETLSGG EAQRIRLASQ IGAGLVGVMY VLDEPSIGLH QRDNERLLGT LIHLRDLGNT 540
  541 VIVVEHDEDA IRAADHVIDI GPGAGVHGGE VVAEGPLEAI MAVPESLTGQ YMSG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.0
Match:	1yqtA
Description:	RNase-L Inhibitor
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [595-668]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRKIEVPKKR VPANPEKVLK LTGARGNNLK DVTLTLPVGL FTCITGVSGS GKSTLINDTL  60
   61 FPIAQRQLNG ATIA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.67
Match:	1l2tA
Description:	MJ0796
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.412582209182696	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [669-940]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPAPYRDIQG LEHFDKVIDI DQSPIGRTPR SNPATYTGVF TPVRELFAGV PESRARGYTP  60
   61 GRFSFNVRGG RCEACQGDGV IKVEMHFLPD IYVPCDQCKG KRYNRETLEI KYKGKTIHEV 120
  121 LDMTIEEARE FFDAVPALAR KLQTLMDVGL TYIRLGQSAT TLSGGEAQRV KLARELSKRG 180
  181 TGQTLYILDE PTTGLHFADI QQLLDVLHKL RDQGNTIVVI EHNLDVIKTA DWIVDLGPEG 240
  241 GSGGGEILVS GTPETVAECE ASHTARFLKP ML

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.0
Match:	2d62A
Description:	No description for 2d62A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: