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View Structure Prediction Details

Protein: UPPS_STRPY
Organism: Streptococcus pyogenes
Length: 249 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UPPS_STRPY.

Description E-value Query
Range
Subject
Range
UPPS_THETN - Undecaprenyl pyrophosphate synthase OS=Thermoanaerobacter tengcongensis GN=uppS PE=3 SV=1
gi|223488732, gi... - gi|254479462|ref|ZP_05092789.1| undecaprenyl pyrophosphate synthetase 1 [Carboxydibrachium pacificum...
ISPT_CALS4 - Isoprenyl transferase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM ...
355.0 [0..1] [249..1]

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Predicted Domain #1
Region A:
Residues: [1-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGLKAKSTK KVLGSIPKHI GIIMDGNGRW AKKRLKPRVF GHKAGMDALQ EVTITASELG  60
   61 VKVLTVYAFS TENWSRPQDE VSFIMNLPVT FFDKYVPVLH ENNVKIQMIG ETSRLPEDTL 120
  121 AALNAAIDKT KRNTGLILNF ALNYGGRAEI TSAVRFIAQD VLDAKLNPGD ITEDLIANYL 180
  181 MTDHLPYLYR DPDLIIRTSG ELRLSNFLPW QSAYSEFYFT PVLWPDFKKA ELLKAIADYN 240
  241 RRQRRFGKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.39794
Match: 1f75A
Description: Undecaprenyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
prenyltransferase activity 4.40397054534951 bayes_pls_golite062009
di-trans,poly-cis-decaprenylcistransferase activity 3.07573514495519 bayes_pls_golite062009
transferase activity 1.42376896518855 bayes_pls_golite062009
catalytic activity 0.878978773660153 bayes_pls_golite062009
dehydrodolichyl diphosphate synthase activity 0.761527128946352 bayes_pls_golite062009
binding 0.747530931796963 bayes_pls_golite062009
protein binding 0.331797220769091 bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups 0.256467886977999 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle