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View Structure Prediction Details

Protein: TTHY_MONDO
Organism: Monodelphis domestica
Length: 149 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TTHY_MONDO.

Description E-value Query
Range		 Subject
Range
TTHY_ERIEU - Transthyretin OS=Erinaceus europaeus GN=TTR PE=2 SV=1
 207.0 [0..1] [149..1]
TTHY_CROPO - Transthyretin OS=Crocodylus porosus GN=TTR PE=1 SV=1
 207.0 [0..1] [149..1]
TTHY_CHICK - Transthyretin OS=Gallus gallus GN=TTR PE=1 SV=1
 206.0 [0..1] [149..1]
TTHY_RAT - Transthyretin OS=Rattus norvegicus GN=Ttr PE=1 SV=1
 205.0 [0..1] [149..1]
TTHY_TILRU - Transthyretin OS=Tiliqua rugosa GN=TTR PE=1 SV=1
 204.0 [0..1] [149..1]
TTHY_MOUSE - Transthyretin OS=Mus musculus GN=Ttr PE=1 SV=1
 202.0 [0..1] [149..1]
gi|84795344 - gi|84795344|gb|ABC65926.1| transthyretin precursor [Anas platyrhynchos]
 202.0 [0..1] [149..1]
TTHY_BOVIN - Transthyretin OS=Bos taurus GN=TTR PE=1 SV=1
 200.0 [0..1] [148..1]

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Predicted Domain #1
Region A:
Residues: [1-149] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFHSLLLLG LASLLFVSDA APVIHGAEDS KCPLMVKVLD AVRGSPAVNV NVKVFKKSEE  60
   61 QTWEPFATGK TNDYGEIHEL TNDEKFGEGL YKVEFDTFSY WNALGVSPFH EYADVVFKAN 120
  121 DAGHRHYTIA ALLSPYSYST TAVVSNPKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1tfpA
Description: Transthyretin (prealbumin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
thyroid hormone transmembrane transporter activity 3.15713468570674 bayes_pls_golite062009
binding 1.94576284584165 bayes_pls_golite062009
protein binding 0.397288184240483 bayes_pls_golite062009
catalytic activity 0.24846317916908 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle