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View Structure Prediction Details

Protein: TTHY_CHICK
Organism: Gallus gallus
Length: 150 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TTHY_CHICK.

Description E-value Query
Range		 Subject
Range
TTHY_CROPO - Transthyretin OS=Crocodylus porosus GN=TTR PE=1 SV=1
 214.0 [0..1] [150..1]
gi|84795344 - gi|84795344|gb|ABC65926.1| transthyretin precursor [Anas platyrhynchos]
 211.0 [0..1] [150..1]
TTHY_TILRU - Transthyretin OS=Tiliqua rugosa GN=TTR PE=1 SV=1
 209.0 [0..1] [150..1]
TTHY_ERIEU - Transthyretin OS=Erinaceus europaeus GN=TTR PE=2 SV=1
 206.0 [0..1] [150..1]
TTHY_RAT - Transthyretin OS=Rattus norvegicus GN=Ttr PE=1 SV=1
 204.0 [0..1] [149..1]
TTHY_MOUSE - Transthyretin OS=Mus musculus GN=Ttr PE=1 SV=1
 201.0 [0..1] [149..1]
TTHY_BOVIN - Transthyretin OS=Bos taurus GN=TTR PE=1 SV=1
 199.0 [0..1] [149..1]
TTHY_PETBR - Transthyretin OS=Petaurus breviceps GN=TTR PE=1 SV=1
 192.0 [0..1] [150..1]

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Predicted Domain #1
Region A:
Residues: [1-150] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFHSTLLVF LAGLVFLSEA APLVSHGSVD SKCPLMVKVL DAVRGSPAAN VAVKVFKKAA  60
   61 DGTWQDFATG KTTEFGEIHE LTTEEQFVEG VYRVEFDTSS YWKGLGLSPF HEYADVVFTA 120
  121 NDSGHRHYTI AALLSPFSYS TTAVVSDPQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.39794
Match: 1tfpA
Description: Transthyretin (prealbumin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
thyroid hormone transmembrane transporter activity 3.15713468570674 bayes_pls_golite062009
binding 1.04439851410502 bayes_pls_golite062009
catalytic activity 0.24846317916908 bayes_pls_golite062009
protein binding 0.141714040355612 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle