YRC Public Data Repository - Protein Structure Prediction

Protein:	FIS1
Organism:	Homo sapiens
Length:	152 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FIS1.

Description	E-value	Query Range	Subject Range
gi\|114615095 - gi\|114615095\|ref\|XP_001143081.1\| PREDICTED: similar to Fission 1 (mitochondrial outer membrane) homo...	9.0E-62	[1..152]	[245..396]
FIS1_RAT - Mitochondrial fission 1 protein OS=Rattus norvegicus GN=Fis1 PE=1 SV=1	9.0E-55	[1..152]	[1..152]
FIS1_MOUSE - Mitochondrial fission 1 protein OS=Mus musculus GN=Fis1 PE=1 SV=1	2.0E-54	[1..152]	[1..152]
gi\|57087495 - gi\|57087495\|ref\|XP_536854.1\| PREDICTED: similar to Tetratricopeptide repeat protein 11 (TPR repeat p...	1.0E-53	[1..152]	[1..152]
gi\|4929739, gi\|7... - gi\|7705632\|ref\|NP_057152.1\| tetratricopeptide repeat domain 11 [Homo sapiens], gi\|4929739\|gb\|AAD3413...	1.0E-53	[1..152]	[1..152]
FIS1_BOVIN - Mitochondrial fission 1 protein OS=Bos taurus GN=FIS1 PE=2 SV=1	4.0E-53	[1..152]	[1..152]
gi\|38106670, gi\|... - gi\|39975997\|ref\|XP_369389.1\| conserved hypothetical protein [Magnaporthe grisea 70-15], gb\|EAA52947.... gi\|59802875 - gi\|59802875\|gb\|AAX07651.1\| hypothetical protein [Magnaporthe grisea]	2.0E-49	[6..151]	[12..154]
FIS1_NEUCR - Mitochondria fission 1 protein OS=Neurospora crassa GN=fis-1 PE=3 SV=1 FIS1_NEUCR - Mitochondria fission 1 protein OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / D...	4.0E-49	[6..151]	[11..153]
gi\|77748305, gi\|... - gi\|77748305\|gb\|AAI06547.1\| MGC131307 protein [Xenopus laevis], gi\|148236436\|ref\|NP_001090116.1\| hypo...	3.0E-48	[1..151]	[1..151]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE  60
   61 LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK 120
  121 DGLVGMAIVG GMALGVAGLA GLIGLAVSKS KS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.39794
Match:	1pc2A
Description:	Solution structure of human mitochondria fission protein Fis1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.02652482814057	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: