YRC Public Data Repository - Protein Structure Prediction

Protein:	TREA_ECOLI
Organism:	Escherichia coli
Length:	565 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TREA_ECOLI.

Description	E-value	Query Range	Subject Range
TREA_SHIF8 - Periplasmic trehalase OS=Shigella flexneri serotype 5b (strain 8401) GN=treA PE=3 SV=1	497.0	[0..1]	[565..1]
gi\|56479849, gi\|... - gi\|56479849\|ref\|NP_707106.2\| trehalase [Shigella flexneri 2a str. 301], gi\|56383400\|gb\|AAN42813.2\| t... TREA_SHIFL - Periplasmic trehalase OS=Shigella flexneri GN=treA PE=3 SV=2	493.0	[0..1]	[565..1]
TREA_ECOL6 - Periplasmic trehalase OS=Escherichia coli O6 GN=treA PE=3 SV=1 TREA_ECOL6 - Periplasmic trehalase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=treA PE=3 SV...	492.0	[0..1]	[565..1]
gi\|30062721, gi\|... - gi\|30062721\|ref\|NP_836892.1\| trehalase [Shigella flexneri 2a str. 2457T], gi\|30040969\|gb\|AAP16699.1\|...	492.0	[0..1]	[565..1]
TREA_ECOK1 - Periplasmic trehalase OS=Escherichia coli O1:K1 / APEC GN=treA PE=3 SV=1	492.0	[0..1]	[565..1]
TREA_ECO45 - Periplasmic trehalase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=treA PE=3 SV=1 TREA_ECOUT - Periplasmic trehalase OS=Escherichia coli (strain UTI89 / UPEC) GN=treA PE=3 SV=1 gi\|237705159, gi... - gi\|237705159\|ref\|ZP_04535640.1\| trehalase [Escherichia sp. 3_2_53FAA], gi\|226899916\|gb\|EEH86175.1\| t...	492.0	[0..1]	[565..1]
TREA_ECOL5 - Periplasmic trehalase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=treA PE=3 SV=1 gi\|191170980, gi... - gi\|191170980\|ref\|ZP_03032531.1\| alpha,alpha-trehalase [Escherichia coli F11], gi\|190908712\|gb\|EDV683...	491.0	[0..1]	[565..1]
TREA_SHIDS - Periplasmic trehalase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=treA PE=3 SV=1	488.0	[0..1]	[564..1]
TREA_ECO57 - Putative periplasmic trehalase OS=Escherichia coli O157:H7 GN=treA PE=5 SV=2	483.0	[0..1]	[565..1]
gi\|75233906 - gi\|75233906\|ref\|ZP_00718366.1\| COG1626: Neutral trehalase [Escherichia coli E110019]	479.0	[0..12]	[565..1]

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Predicted Domain #1

Region A:
Residues: [1-565]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSPAPSRPQ KMALIPACIF LCFAALSVQA EETPVTPQPP DILLGPLFND VQNAKLFPDQ  60
   61 KTFADAVPNS DPLMILADYR MQQNQSGFDL RHFVNVNFTL PKEGEKYVPP EGQSLREHID 120
  121 GLWPVLTRST ENTEKWDSLL PLPEPYVVPG GRFREVYYWD SYFTMLGLAE SGHWDKVADM 180
  181 VANFAHEIDT YGHIPNGNRS YYLSRSQPPF FALMVELLAQ HEGDAALKQY LPQMQKEYAY 240
  241 WMDGVENLQA GQQEKRVVKL QDGTLLNRYW DDRDTPRPES WVEDIATAKS NPNRPATEIY 300
  301 RDLRSAAASG WDFSSRWMDN PQQLNTLRTT SIVPVDLNSL MFKMEKILAR ASKAAGDNAM 360
  361 ANQYETLANA RQKGIEKYLW NDQQGWYADY DLKSHKVRNQ LTAAALFPLY VNAAAKDRAN 420
  421 KMATATKTHL LQPGGLNTTS VKSGQQWDAP NGWAPLQWVA TEGLQNYGQK EVAMDISWHF 480
  481 LTNVQHTYDR EKKLVEKYDV STTGTGGGGG EYPLQDGFGW TNGVTLKMLD LICPKEQPCD 540
  541 NVPATRPTVK SATTQPSTKE AQPTP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.0
Match:	2jf4A
Description:	No description for 2jf4A was found.

Predicted functions:

Term	Confidence	Notes
trehalase activity	8.21995956919006	bayes_pls_golite062009
alpha,alpha-trehalase activity	8.15034892377685	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	2.91663376644963	bayes_pls_golite062009
hydrolase activity	1.70627242352696	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	1.61226907827219	bayes_pls_golite062009
catalytic activity	1.16285856935495	bayes_pls_golite062009
binding	0.614457867010069	bayes_pls_golite062009
protein binding	0.31260719357226	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: