YRC Public Data Repository - Protein Structure Prediction

Protein:	SPY_ECOLI
Organism:	Escherichia coli
Length:	161 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPY_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|82776812, gi\|... - gi\|82776812\|ref\|YP_403161.1\| periplasmic protein [Shigella dysenteriae Sd197], gi\|81240960\|gb\|ABB616...	120.0	[0..1]	[161..1]
gi\|254161802, gi... - gi\|254161802\|ref\|YP_003044910.1\| envelope stress induced periplasmic protein [Escherichia coli B str... SPY_ECOBD - Periplasmic chaperone Spy OS=Escherichia coli (strain B / BL21-DE3) GN=spy PE=1 SV=1 gi\|194438564, gi... - gi\|83586042\|ref\|ZP_00924680.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|242377464, gi... - gi\|251785191\|ref\|YP_002999495.1\| hypothetical protein B21_01700 [Escherichia coli BL21], gi\|24237746...	112.0	[0..1]	[161..1]
gi\|117623915, gi... - gi\|117623915\|ref\|YP_852828.1\| periplasmic protein [Escherichia coli APEC O1], gi\|115513039\|gb\|ABJ011... gi\|91210959, gi\|... - gi\|91210959\|ref\|YP_540945.1\| periplasmic protein [Escherichia coli UTI89], gi\|91072533\|gb\|ABE07414.1... gi\|218558611, gi... - gi\|218558611\|ref\|YP_002391524.1\| periplasmic protein [Escherichia coli S88], gi\|218365380\|emb\|CAR031... gi\|237705693, gi... - gi\|237705693\|ref\|ZP_04536174.1\| spheroplast protein Y [Escherichia sp. 3_2_53FAA], gi\|226900450\|gb\|E...	111.0	[0..1]	[161..1]
gi\|215265032, gi... - gi\|215486960\|ref\|YP_002329391.1\| periplasmic protein [Escherichia coli O127:H6 str. E2348/69], gi\|21... gi\|218427248, gi... - gi\|218689684\|ref\|YP_002397896.1\| periplasmic protein [Escherichia coli ED1a], gi\|218427248\|emb\|CAR08... gi\|110641863, gi... - gi\|110641863\|ref\|YP_669593.1\| periplasmic protein [Escherichia coli 536], gi\|110343455\|gb\|ABG69692.1... gi\|227885832, gi... - gi\|227885832\|ref\|ZP_04003637.1\| periplasmic protein [Escherichia coli 83972], gi\|227837405\|gb\|EEJ478... gi\|191171743, gi... - gi\|75241382\|ref\|ZP_00725233.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|26108400, gi\|... - gi\|26247997\|ref\|NP_754037.1\| periplasmic protein [Escherichia coli CFT073], gi\|26108400\|gb\|AAN80602....	110.0	[0..1]	[161..1]
gi\|194433460, gi... - gi\|83569653\|ref\|ZP_00921104.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|157158229, gi... - gi\|75190776\|ref\|ZP_00704043.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|194428505, gi... - gi\|75210230\|ref\|ZP_00710398.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|190900391, gi... - gi\|75227070\|ref\|ZP_00713894.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|193068938, gi... - gi\|75236788\|ref\|ZP_00720859.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|193065814, gi... - gi\|75256145\|ref\|ZP_00727841.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|168749439, gi... - gi\|188016249\|gb\|EDU54371.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4113], gi\|1687494... gi\|168756748, gi... - gi\|189356145\|gb\|EDU74564.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4401], gi\|1687567... SPY_ECO57 - Periplasmic chaperone Spy OS=Escherichia coli O157:H7 GN=spy PE=1 SV=1 gi\|168762189, gi... - gi\|189367468\|gb\|EDU85884.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4501], gi\|1687621... gi\|25380130, gi\|... - pir\|\|E85783 hypothetical protein spy [imported] - Escherichia coli (strain O157:H7, substrain EDL93... gi\|189360598, gi... - gi\|189360598\|gb\|EDU79017.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4486], gi\|1687705... gi\|12515762, gi\|... - gi\|15802154\|ref\|NP_288176.1\| periplasmic protein [Escherichia coli O157:H7 EDL933], gi\|12515762\|gb\|A... gi\|209161296, gi... - gi\|209399896\|ref\|YP_002270812.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|209919104, gi... - gi\|209919104\|ref\|YP_002293188.1\| periplasmic protein [Escherichia coli SE11], gi\|209912363\|dbj\|BAG77... gi\|217328829, gi... - gi\|217328829\|ref\|ZP_03444910.1\| spheroplast protein Y [Escherichia coli O157:H7 str. TW14588], gi\|21... gi\|254793361, gi... - gi\|254793361\|ref\|YP_003078198.1\| envelope stress induced periplasmic protein [Escherichia coli O157:... gi\|218361077, gi... - gi\|218554309\|ref\|YP_002387222.1\| periplasmic protein [Escherichia coli IAI1], gi\|218361077\|emb\|CAQ98... gi\|218369676, gi... - gi\|218699690\|ref\|YP_002407319.1\| periplasmic protein [Escherichia coli IAI39], gi\|218369676\|emb\|CAR1... gi\|218432338, gi... - gi\|218705241\|ref\|YP_002412760.1\| periplasmic protein [Escherichia coli UMN026], gi\|218432338\|emb\|CAR... gi\|124529977, gi... - gi\|124529977\|ref\|ZP_01700789.1\| protein of unknown function, Spy-related [Escherichia coli B], gi\|12... gi\|187769494, gi... - gi\|187769494\|gb\|EDU33338.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4196], gi\|1687749... gi\|189000278, gi... - gi\|189000278\|gb\|EDU69264.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4076], gi\|1687821... gi\|189371992, gi... - gi\|189371992\|gb\|EDU90408.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC869], gi\|16878814... gi\|189377578, gi... - gi\|189377578\|gb\|EDU95994.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC508], gi\|16880007... gi\|169754838, gi... - gi\|170019910\|ref\|YP_001724864.1\| periplasmic protein [Escherichia coli ATCC 8739], gi\|169754838\|gb\|A... gi\|195937427 - gi\|195937427\|ref\|ZP_03082809.1\| periplasmic protein [Escherichia coli O157:H7 str. EC4024] gi\|208810309, gi... - gi\|208810309\|ref\|ZP_03252185.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|208816818, gi... - gi\|208816818\|ref\|ZP_03257938.1\| spheroplast protein Y [Escherichia coli O157:H7 str. EC4045], gi\|208... gi\|15831703, gi\|... - gi\|15831703\|ref\|NP_310476.1\| periplasmic protein [Escherichia coli O157:H7 str. Sakai], gi\|13361916\|...	109.0	[0..1]	[161..1]
gi\|24051797, gi\|... - gi\|24112858\|ref\|NP_707368.1\| periplasmic protein [Shigella flexneri 2a str. 301], gi\|24051797\|gb\|AAN... gi\|110805449, gi... - gi\|110805449\|ref\|YP_688969.1\| periplasmic protein [Shigella flexneri 5 str. 8401], gi\|110614997\|gb\|A... gi\|30062990, gi\|... - gi\|30062990\|ref\|NP_837161.1\| periplasmic protein [Shigella flexneri 2a str. 2457T], gi\|30041239\|gb\|A...	109.0	[0..1]	[161..1]
gi\|25380129 - pir\|\|AC0010 probable exported protein cpxP [imported] - Yersinia pestis (strain CO92) gi\|162420508, gi... - gi\|77633895\|ref\|ZP_00796008.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|229904465, gi... - gi\|229904465\|ref\|ZP_04519576.1\| P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc- ... gi\|149290271, gi... - gi\|150260863\|ref\|ZP_01917591.1\| putative exported protein [Yersinia pestis CA88-4125], gi\|149290271\|... gi\|153950411, gi... - gi\|77630849\|ref\|ZP_00793435.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|22123987, gi\|... - gi\|22123987\|ref\|NP_667410.1\| periplasmic stress adaptor protein CpxP [Yersinia pestis KIM], gi\|21956... gi\|27544275 - gi\|27544275\|dbj\|BAC54910.1\| hypothetical protein [Yersinia pseudotuberculosis] gi\|229706636, gi... - gi\|229836188\|ref\|ZP_04456356.1\| P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc- ... gi\|218927294, gi... - gi\|218927294\|ref\|YP_002345169.1\| periplasmic stress adaptor protein CpxP [Yersinia pestis CO92], gi\|... gi\|229839924, gi... - gi\|229839924\|ref\|ZP_04460083.1\| P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc- ... gi\|45439939, gi\|... - gi\|45439939\|ref\|NP_991478.1\| periplasmic stress adaptor protein CpxP [Yersinia pestis biovar Microtu... gi\|229842006, gi... - gi\|229842006\|ref\|ZP_04462161.1\| P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc- ... gi\|165936156, gi... - gi\|89103446\|ref\|ZP_01176023.1\| COG3678: P pilus assembly/Cpx signaling pathway, periplasmic inhibito... gi\|108809459, gi... - gi\|108809459\|ref\|YP_653375.1\| periplasmic stress adaptor protein CpxP [Yersinia pestis Antiqua], gi\|... gi\|165989621, gi... - gi\|166011475\|ref\|ZP_02232373.1\| conserved hypothetical protein [Yersinia pestis biovar Antiqua str. ... gi\|165926138, gi... - gi\|165926138\|ref\|ZP_02221970.1\| conserved hypothetical protein [Yersinia pestis biovar Orientalis st... gi\|167398953, gi... - gi\|167398953\|ref\|ZP_02304477.1\| conserved hypothetical protein [Yersinia pestis biovar Antiqua str. ... gi\|166213737, gi... - gi\|166213737\|ref\|ZP_02239772.1\| conserved hypothetical protein [Yersinia pestis biovar Antiqua str. ... gi\|167054373, gi... - gi\|167426684\|ref\|ZP_02318437.1\| conserved hypothetical protein [Yersinia pestis biovar Mediaevalis s... gi\|167419212, gi... - gi\|167419212\|ref\|ZP_02310965.1\| conserved hypothetical protein [Yersinia pestis biovar Orientalis st... gi\|170026338, gi... - gi\|170026338\|ref\|YP_001722843.1\| periplasmic stress adaptor protein CpxP [Yersinia pseudotuberculosi... gi\|167468393 - gi\|167468393\|ref\|ZP_02333097.1\| hypothetical protein YpesF_10944 [Yersinia pestis FV-1]	107.0	[0..1]	[161..1]
Q66GB1\|Q66GB1_YERPS - Putative exported protein precursor - Yersinia pseudotuberculosis gi\|51587711, gi\|... - gi\|51594429\|ref\|YP_068620.1\| periplasmic stress adaptor protein CpxP [Yersinia pseudotuberculosis IP... gi\|186893416, gi... - gi\|186893416\|ref\|YP_001870528.1\| periplasmic stress adaptor protein CpxP [Yersinia pseudotuberculosi...	107.0	[0..1]	[161..1]
gi\|213162968 - gi\|213162968\|ref\|ZP_03348678.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typ... gi\|29137280, gi\|... - gi\|29141652\|ref\|NP_804994.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typhi ... gi\|213583600 - gi\|213583600\|ref\|ZP_03365426.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typ... gi\|16760587 - gi\|16760587\|ref\|NP_456204.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typhi ... gi\|213646941 - gi\|213646941\|ref\|ZP_03376994.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typ... gi\|213852612 - gi\|213852612\|ref\|ZP_03382144.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typ... gi\|25380134, gi\|... - gi\|25380134\|pir\|\|AE0709 probable exported protein STY1805 [imported] - Salmonella enterica subsp. en... gi\|214003064 - gi\|214003064\|ref\|ZP_03413799.1\| periplasmic protein [Salmonella enterica subsp. enterica serovar Typ...	103.0	[0..1]	[161..1]
gi\|197262764, gi... - gi\|197262764\|ref\|ZP_03162838.1\| spheroplast protein Y [Salmonella enterica subsp. enterica serovar S... gi\|204927529, gi... - gi\|204927529\|ref\|ZP_03218730.1\| spheroplast protein Y [Salmonella enterica subsp. enterica serovar J... gi\|205341551, gi... - gi\|205341551\|gb\|EDZ28315.1\| spheroplast protein Y [Salmonella enterica subsp. enterica serovar Welte... gi\|194710951, gi... - gi\|194735449\|ref\|YP_002114327.1\| spheroplast protein Y [Salmonella enterica subsp. enterica serovar ... gi\|16419826, gi\|... - gi\|16764659\|ref\|NP_460274.1\| periplasmic protein [Salmonella typhimurium LT2], gi\|16419826\|gb\|AAL202... gi\|205329797, gi... - gi\|205329797\|gb\|EDZ16561.1\| spheroplast protein Y [Salmonella enterica subsp. enterica serovar 4,[5]... gi\|168238976, gi... - gi\|197288243\|gb\|EDY27628.1\| spheroplast protein Y [Salmonella enterica subsp. enterica serovar Schwa... lcl\|NC_016856.1_... - [gene=spy] [protein=hypothetical protein] [protein_id=YP_005237163.1] [location=1398533..1399018]	103.0	[0..1]	[161..1]

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Predicted Domain #1

Region A:
Residues: [1-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKLTALFVA STLALGAANL AHAADTTTAA PADAKPMMHH KGKFGPHQDM MFKDLNLTDA  60
   61 QKQQIREIMK GQRDQMKRPP LEERRAMHDI IASDTFDKVK AEAQIAKMEE QRKANMLAHM 120
  121 ETQNKIYNIL TPEQKKQFNA NFEKRLTERP AAKGKMPATA E

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.872	a.118.7	14-3-3 protein
View	Download	0.703	a.24.14	FAT domain of focal adhesion kinase
View	Download	0.582	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore
View	Download	0.573	a.24.14	FAT domain of focal adhesion kinase
View	Download	0.561	d.67.3	Ribosome recycling factor, RRF

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits