YRC Public Data Repository - Protein Structure Prediction

Protein:	RMLA_NEIMB
Organism:	Neisseria meningitidis serogroup B
Length:	288 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RMLA_NEIMB.

Description	E-value	Query Range	Subject Range
gi\|68196230, gi\|... - gi\|69244639\|ref\|ZP_00602903.1\| Glucose-1-phosphate thymidylyltransferase, long form [Enterococcus fa... gi\|48826109 - ref\|ZP_00287334.1\| COG1209: dTDP-glucose pyrophosphorylase [Enterococcus faecium]	301.0	[0..1]	[288..1]
gi\|227175529, gi... - gi\|227555318\|ref\|ZP_03985365.1\| glucose-1-phosphate thymidylyltransferase [Enterococcus faecalis HH2... gi\|229309642, gi... - gi\|229545292\|ref\|ZP_04434017.1\| glucose-1-phosphate thymidylyltransferase [Enterococcus faecalis TX1... gi\|3608394\|gb\|AA... - putative glucose-1-phosphate thymidyl transferase [Enterococcus faecalis] gi\|227520249, gi... - gi\|227520249\|ref\|ZP_03950298.1\| glucose-1-phosphate thymidylyltransferase [Enterococcus faecalis TX0... gi\|29376702, gi\|... - gi\|29376702\|ref\|NP_815856.1\| glucose-1-phosphate thymidylyltransferase [Enterococcus faecalis V583],... gi\|3608394 - gi\|3608394\|gb\|AAC35920.1\| putative glucose-1-phosphate thymidyl transferase [Enterococcus faecalis] gi\|229549527, gi... - gi\|229549527\|ref\|ZP_04438252.1\| glucose-1-phosphate thymidylyltransferase [Enterococcus faecalis ATC... gi\|238829616, gi... - gi\|238857705\|ref\|ZP_04647935.1\| glucose-1-phosphate thymidylyltransferase [Enterococcus faecalis TUS...	300.0	[0..1]	[288..1]
gi\|1098479 - gi\|1098479\|gb\|AAC37050.1\| glucose-1-phosphate thymidyl transferase [Neisseria meningitidis]	299.0	[0..1]	[288..14]
gi\|83746221, gi\|... - gi\|83746221\|ref\|ZP_00943275.1\| Glucose-1-phosphate thymidylyltransferase [Ralstonia solanacearum UW5...	299.0	[0..2]	[288..72]
gi\|115279742, gi... - gi\|29725990\|gb\|AAO88922.1\| glucose-1-phosphate thymidylyltransferase [Vibrio cholerae], gi\|115279742...	298.0	[0..1]	[288..1]
RMLA_NEIMA - Glucose-1-phosphate thymidylyltransferase OS=Neisseria meningitidis serogroup A GN=rmlA1 PE=3 SV=1 RMLA_NEIMA - Glucose-1-phosphate thymidylyltransferase OS=Neisseria meningitidis serogroup A / serotype 4A (strai... gi\|11261721 - pir\|\|H82014 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) NMA0205 [imported] - Neisseria m...	298.0	[0..1]	[288..1]
gi\|16357459 - gi\|16357459\|gb\|AAK27854.2\|AF324836_7 glucose 1-phosphate thymidyltransferase [Aneurinibacillus therm...	298.0	[0..1]	[288..1]
gi\|72132990 - gi\|72132990\|gb\|AAZ66343.1\| RmlA [Listonella anguillarum]	297.0	[0..1]	[288..1]
gi\|116516051, gi... - gi\|4200433\|gb\|AAD10181.1\| Cps2L [Streptococcus pneumoniae D39], gi\|116516051\|ref\|YP_815843.1\| glucos... gi\|68642333, gi\|... - gi\|68642333\|emb\|CAI32754.1\| glucose-1-phosphate thymidylyltransferase RmlA [Streptococcus pneumoniae... gi\|15457875, gi\|... - gi\|15902364\|ref\|NP_357914.1\| hypothetical protein spr0320 [Streptococcus pneumoniae R6], gi\|15457875...	297.0	[0..1]	[288..1]
gi\|90962543, gi\|... - gi\|90962543\|ref\|YP_536459.1\| glucose-1-phosphate thymidylyltransferase [Lactobacillus salivarius UCC...	296.0	[0..1]	[288..1]

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Predicted Domain #1

Region A:
Residues: [1-288]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGIILAGGS GTRLYPITRG VSKQLLPVYD KPMIYYPLSV LMLAGIRDIL VITAPEDNAS  60
   61 FKRLLGDGSD FGISISYAVQ PSPDGLAQAF IIGEEFIGND NVCLVLGDNI FYGQSFTQTL 120
  121 KQAAAQTHGA TVFAYQVKNP ERFGVVEFNE NFRAVSIEEK PQRPKSDWAV TGLYFYDNRA 180
  181 VEFAKQLKPS ARGELEITDL NRMYLEDGSL SVQILGRGFA WLDTGTHESL HEAASFVQTV 240
  241 QNIQNLHIAC LEEIAWRNGW LSDEKLEELA RPMAKNQYGQ YLLRLLKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.154902
Match:	1mc3A
Description:	RffH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uridylyltransferase activity	3.74072767898515	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.70047942699289	bayes_pls_golite062009
UTP:glucose-1-phosphate uridylyltransferase activity	2.65167602524122	bayes_pls_golite062009
UTP-monosaccharide-1-phosphate uridylyltransferase activity	2.46432078102948	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.33861720107822	bayes_pls_golite062009
transferase activity	2.17535315350752	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	1.33788133706753	bayes_pls_golite062009
nucleotidyltransferase activity	1.17054423506287	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	1.10309252319727	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.02084820914491	bayes_pls_golite062009
cytidylyltransferase activity	0.983416157001861	bayes_pls_golite062009
mannosyltransferase activity	0.91123217364068	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.897978517422275	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.513376694534047	bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity	0.2363835251362	bayes_pls_golite062009
guanylyltransferase activity	0.0539392112504681	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: