YRC Public Data Repository - Protein Structure Prediction

Protein:	RIBF_ECOLI
Organism:	Escherichia coli
Length:	313 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIBF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|83584931 - gi\|83584931\|ref\|ZP_00923588.1\| COG0196: FAD synthase [Escherichia coli 101-1]	323.0	[0..1]	[313..1]
gi\|82775427, gi\|... - gi\|82775427\|ref\|YP_401774.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Shigella dysent...	321.0	[0..1]	[313..1]
gi\|124498642, gi... - gi\|124531342\|ref\|ZP_01701670.1\| riboflavin biosynthesis protein RibF [Escherichia coli B], gi\|124498... gi\|170021616, gi... - gi\|170021616\|ref\|YP_001726570.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Escherichia... gi\|253972052, gi... - gi\|254160151\|ref\|YP_003043259.1\| putative regulator [Escherichia coli B str. REL606], gi\|253972052\|g... gi\|253976261, gi... - gi\|254286954\|ref\|YP_003052702.1\| putative regulator [Escherichia coli BL21(DE3)], gi\|253976261\|gb\|AC... gi\|188495589, gi... - gi\|75515613\|ref\|ZP_00737770.1\| COG0196: FAD synthase [Escherichia coli 53638], gi\|188495589\|ref\|ZP_0... gi\|251783592, gi... - gi\|251783592\|ref\|YP_002997896.1\| hypothetical protein B21_00028 [Escherichia coli BL21], gi\|24237586...	321.0	[0..1]	[313..1]
gi\|82542641, gi\|... - gi\|82542641\|ref\|YP_406588.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Shigella boydii...	321.0	[0..1]	[313..1]
gi\|194430667, gi... - gi\|75207957\|ref\|ZP_00708393.1\| COG0196: FAD synthase [Escherichia coli B171], gi\|194430667\|ref\|ZP_03...	320.0	[0..1]	[313..1]
gi\|91227671, gi\|... - gi\|91227671\|ref\|ZP_01261948.1\| hypothetical protein V12G01_13339 [Vibrio alginolyticus 12G01], gi\|91...	317.0	[0..1]	[311..1]
gi\|75853599, gi\|... - gi\|75853599\|ref\|ZP_00761405.1\| COG0196: FAD synthase [Vibrio sp. Ex25], gi\|254230239\|ref\|ZP_04923630...	316.0	[0..1]	[311..1]
gi\|148875139, gi... - gi\|153829356\|ref\|ZP_01982023.1\| riboflavin kinase/FMN adenylyltransferase [Vibrio cholerae 623-39], ... gi\|153826783, gi... - gi\|153826783\|ref\|ZP_01979450.1\| riboflavin kinase/FMN adenylyltransferase [Vibrio cholerae MZO-2], g... gi\|75814478, gi\|... - gi\|75814478\|ref\|ZP_00745061.1\| COG0196: FAD synthase [Vibrio cholerae V52], gi\|121730023\|ref\|ZP_0168... gi\|124114898, gi... - gi\|153215107\|ref\|ZP_01949814.1\| riboflavin kinase/FMN adenylyltransferase [Vibrio cholerae 1587], gi... gi\|254291959, gi... - gi\|254291959\|ref\|ZP_04962739.1\| riboflavin kinase/FMN adenylyltransferase [Vibrio cholerae AM-19226]...	314.0	[0..1]	[311..1]
gi\|75826041, gi\|... - gi\|75826041\|ref\|ZP_00755476.1\| COG0196: FAD synthase [Vibrio cholerae O395], gi\|227117056\|ref\|YP_002...	314.0	[0..1]	[311..1]
gi\|238910799 - gi\|238910799\|ref\|ZP_04654636.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella e... gi\|168464424, gi... - gi\|195632986\|gb\|EDX51440.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|205342427, gi... - gi\|205342427\|gb\|EDZ29191.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|194442807, gi... - gi\|194442807\|ref\|YP_002039275.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. en... gi\|62126242, gi\|... - gi\|62178609\|ref\|YP_215026.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella ente... gi\|194469211, gi... - gi\|194469211\|ref\|ZP_03075195.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. ent... lcl\|NC_016856.1_... - [gene=ribF] [protein=bifunctional riboflavin kinase/FMN adenylyltransferase] [protein_id=YP_00523568... gi\|167989898, gi... - gi\|205331395\|gb\|EDZ18159.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|205335177, gi... - gi\|205335177\|gb\|EDZ21941.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|168234788, gi... - gi\|197292041\|gb\|EDY31391.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|205348861, gi... - gi\|205348861\|gb\|EDZ35492.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|167550783, gi... - gi\|205324347\|gb\|EDZ12186.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. enteric... gi\|29140589, gi\|... - gi\|29140589\|ref\|NP_803931.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella ente... gi\|214001175 - gi\|214001175\|ref\|ZP_03411910.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella e... gi\|16759039 - gi\|16759039\|ref\|NP_454656.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella ente... gi\|224466409, gi... - gi\|224581882\|ref\|YP_002635680.1\| hypothetical protein SPC_0047 [Salmonella enterica subsp. enterica ... gi\|25302150, gi\|... - gi\|25302150\|pir\|\|AH0507 FMN adenylyltransferase (EC 2.7.7.2) - Salmonella enterica subsp. enterica s... gi\|16418540, gi\|... - gi\|16763435\|ref\|NP_459050.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella typh... gi\|204927078, gi... - gi\|204927078\|ref\|ZP_03218280.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. ent... gi\|206707364, gi... - gi\|207855561\|ref\|YP_002242212.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella ... gi\|213163430 - gi\|213163430\|ref\|ZP_03349140.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella e... gi\|213852259 - gi\|213852259\|ref\|ZP_03381791.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Salmonella e... gi\|194710470, gi... - gi\|194734968\|ref\|YP_002113056.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. en... gi\|197212556, gi... - gi\|197248853\|ref\|YP_002145026.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. en... gi\|197240990, gi... - gi\|197262735\|ref\|ZP_03162809.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. ent... gi\|199603744, gi... - gi\|200386646\|ref\|ZP_03213258.1\| riboflavin biosynthesis protein RibF [Salmonella enterica subsp. ent...	313.0	[0..1]	[310..1]

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Predicted Domain #1

Region A:
Residues: [1-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLIRGIHNL SQAPQEGCVL TIGNFDGVHR GHRALLQGLQ EEGRKRNLPV MVMLFEPQPL  60
   61 ELFATDKAPA RLTRLREKLR YLAECGVDYV LCVRFDRRFA ALTAQNFISD LLVKHLRVKF 120
  121 LAVGDDFRFG AGREGDFLLL QKAGMEYGFD ITSTQTFCEG GVRISSTAVR QALADDNLAL 180
  181 AESLLGHPFA ISGRVVHGDE LGRTIGFPTA NVPLRRQVSP VKGVYAVEVL GLGEKPLPGV 240
  241 ANIGTRPTVA GIRQQLEVHL LDVAMDLYGR HIQVVLRKKI RNEQRFASLD ELKAQIARDE 300
  301 LTAREFFGLT KPA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.154902
Match:	1mrzA
Description:	Crystal structure of a flavin binding protein from Thermotoga Maritima, TM379
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.84668360172717	bayes_pls_golite062009
kinase activity	0.7211756790235	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.70842009684549	bayes_pls_golite062009
riboflavin kinase activity	0.642106611415199	bayes_pls_golite062009
ligase activity	0.41353894226697	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	0.1911539125531	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	0.1911539125531	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	0.178548924377401	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: