YRC Public Data Repository - Protein Structure Prediction

Protein:	RHSE_ECOLI
Organism:	Escherichia coli
Length:	682 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RHSE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|4377518 - gi\|4377518\|emb\|CAA43309.1\| RhsE protein [Escherichia coli]	514.0	[0..2]	[682..1]
gi\|157158534, gi... - gi\|75189325\|ref\|ZP_00702592.1\| COG3209: Rhs family protein [Escherichia coli E24377A], gi\|157158534\|...	514.0	[0..3]	[682..736]
gi\|75258778, gi\|... - gi\|75258778\|ref\|ZP_00730168.1\| COG3209: Rhs family protein [Escherichia coli E22], gi\|193063195\|ref\|... gi\|75211212, gi\|... - gi\|75211212\|ref\|ZP_00711319.1\| COG3209: Rhs family protein [Escherichia coli B171], gi\|194427594\|ref...	511.0	[0..3]	[682..736]
gi\|188489063, gi... - gi\|75514958\|ref\|ZP_00737162.1\| COG3209: Rhs family protein [Escherichia coli 53638], gi\|188493864\|re...	501.0	[0..3]	[682..728]
gi\|194424460, gi... - gi\|83587798\|ref\|ZP_00926424.1\| COG3209: Rhs family protein [Escherichia coli 101-1], gi\|194436428\|re...	485.0	[0..3]	[682..248]
gi\|188015567, gi... - gi\|188015567\|gb\|EDU53689.1\| protein RhsE [Escherichia coli O157:H7 str. EC4113], gi\|168750197\|ref\|ZP... gi\|189355706, gi... - gi\|189355706\|gb\|EDU74125.1\| protein RhsE [Escherichia coli O157:H7 str. EC4401], gi\|168757242\|ref\|ZP... gi\|168763455, gi... - gi\|189366364\|gb\|EDU84780.1\| protein RhsE [Escherichia coli O157:H7 str. EC4501], gi\|168763455\|ref\|ZP... gi\|15829496, gi\|... - gi\|15829496\|ref\|NP_308269.1\| Rhs core protein [Escherichia coli O157:H7], gi\|13359698\|dbj\|BAB33665.1... gi\|25500887, gi\|... - pir\|\|H85509 hypothetical protein Z0272 [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|15799920, gi\|... - gi\|15799920\|ref\|NP_285932.1\| hypothetical protein Z0272 [Escherichia coli O157:H7 EDL933], gi\|125129... gi\|15829496, gi\|... - gi\|15829496\|ref\|NP_308269.1\| Rhs core protein [Escherichia coli O157:H7 str. Sakai], gi\|13359698\|dbj... gi\|209162309, gi... - gi\|209400909\|ref\|YP_002268844.1\| RHS Repeat family protein [Escherichia coli O157:H7 str. EC4115], g... gi\|217326357, gi... - gi\|217326357\|ref\|ZP_03442441.1\| RHS Repeat family protein [Escherichia coli O157:H7 str. TW14588], g... gi\|195938620 - gi\|195938620\|ref\|ZP_03084002.1\| Rhs core protein [Escherichia coli O157:H7 str. EC4024] gi\|208807889, gi... - gi\|208807889\|ref\|ZP_03250226.1\| RHS Repeat family protein [Escherichia coli O157:H7 str. EC4206], gi... gi\|208813901, gi... - gi\|208813901\|ref\|ZP_03255230.1\| RHS Repeat family protein [Escherichia coli O157:H7 str. EC4045], gi... gi\|208820181, gi... - gi\|208820181\|ref\|ZP_03260501.1\| RHS Repeat family protein [Escherichia coli O157:H7 str. EC4042], gi... gi\|189361088, gi... - gi\|189361088\|gb\|EDU79507.1\| protein RhsE [Escherichia coli O157:H7 str. EC4486], gi\|168770012\|ref\|ZP... gi\|187768451, gi... - gi\|187768451\|gb\|EDU32295.1\| protein RhsE [Escherichia coli O157:H7 str. EC4196], gi\|168776147\|ref\|ZP... gi\|188999654, gi... - gi\|188999654\|gb\|EDU68640.1\| protein RhsE [Escherichia coli O157:H7 str. EC4076], gi\|168782974\|ref\|ZP... gi\|189377328, gi... - gi\|189377328\|gb\|EDU95744.1\| protein RhsE [Escherichia coli O157:H7 str. EC508], gi\|168800348\|ref\|ZP_... gi\|254590775, gi... - gi\|254791375\|ref\|YP_003076212.1\| hypothetical protein ECSP_0248 [Escherichia coli O157:H7 str. TW143...	438.0	[0..99]	[682..4]
gi\|157068639, gi... - gi\|75197408\|ref\|ZP_00707478.1\| COG3209: Rhs family protein [Escherichia coli HS], gi\|157162959\|ref\|Y...	433.0	[0..2]	[600..723]

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Predicted Domain #1

Region A:
Residues: [1-419]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTRLTTLSH TSEGHRVSVH YGYDDKGRLT GERQTVENPE TGELLWHHET GHAYNEQGLA  60
   61 NRVTPDSLPP VEWLTYGSGY LAGMKLGGTP LLEFTRDRLH RETVRSFGSM AGSNAAYKLT 120
  121 STYTPAGQLQ SQHLNSLVYD RDYGWNDNGD LVRISGPRQT REYGYSATGR LESVRTLAPD 180
  181 LDIRIPYATD PAGNRLPDPE LHPDSTLTVW PDNRIAEDAH YVYRHDEYGR LTEKTDRIPA 240
  241 GVIRTDDERT HHYHYDSQHR LVFYTRIQHG EPLVESRYLY DPLGRRMAKR VWRRERDLTG 300
  301 WMSLSRKPEV TWYGWDGDRL TTVQTDTTRI QTVYEPGSFT PLIRVETENG EREKAQRRSL 360
  361 AETLQQEGSE NGHGVVFPAE LVRLLDRLEE EIRADRVSSE SRAWLAQCGL TVEQLARQV

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.3
Match:	2fkgA
Description:	No description for 2fkgA was found.

Predicted Domain #2

Region A:
Residues: [420-547]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPEYTPARKV HFYHCDHRGL PLALISEDGN TAWRGEYDEW GNQLNEENPH HLHQPYRLPG  60
   61 QQHDEESGLY YNRHRHYDPL QGRYITPDPI GLRGGWNMYQ YPLNPIQVID PMGLDAIENM 120
  121 TSGGLIYA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.243	0.001	integral to membrane	c.36.1	Thiamin diphosphate-binding fold (THDP-binding)
View	Download	0.262	0.001	integral to membrane	a.74.1	Cyclin-like
View	Download	0.433	N/A	N/A	d.134.1	Sulfite reductase hemoprotein (SiRHP), domains 2 and 4

Predicted Domain #3

Region A:
Residues: [548-682]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSGVPGLIAA NSITNSAYQF GYDMDAIVGG AHNGAADAMR HCYLMCRMTK TFGSTIADVI  60
   61 GKNHEAAGDR QGQPAKERIM DLKNNTVGIA CGDFSAKCSD ACIEKYNTGQ LFGLDGIKAD 120
  121 NPIKAKQGSS DASNY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.596	a.74.1	Cyclin-like
View	Download	0.595	a.1.1	Globin-like
View	Download	0.559	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore
View	Download	0.532	a.74.1	Cyclin-like
View	Download	0.469	a.29.2	Bromodomain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits