YRC Public Data Repository - Protein Structure Prediction

Protein:	RFAQ_ECOLI
Organism:	Escherichia coli
Length:	344 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFAQ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|3132877 - gi\|3132877\|gb\|AAC69658.1\| WaaQ [Escherichia coli]	241.0	[0..1]	[344..1]
gi\|220932724, gi... - gi\|89211042\|ref\|ZP_01189421.1\| Glycosyl transferase, family 9:Three-deoxy-D-manno-octulosonic-acid t...	237.0	[0..1]	[332..441]
gi\|224613059 - gi\|224613059\|dbj\|BAH24279.1\| ADP-heptose:LPS heptosyltransferase [Escherichia coli B] gi\|83588521 - gi\|83588521\|ref\|ZP_00927145.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli 101-1] gi\|253322571, gi... - gi\|253771527\|ref\|YP_003034358.1\| lipopolysaccharide heptosyltransferase III [Escherichia coli BL21(D... gi\|251786883, gi... - gi\|251786883\|ref\|YP_003001187.1\| hypothetical protein B21_03441 [Escherichia coli BL21], gi\|24237915...	230.0	[0..1]	[331..1]
gi\|54307430, gi\|... - gi\|54307430\|ref\|YP_128450.1\| putative lipopolysaccharide biosynthesis protein [Photobacterium profun...	230.0	[0..1]	[337..16]
gi\|75229023 - gi\|75229023\|ref\|ZP_00715607.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli B7A]	230.0	[0..1]	[334..1]
gi\|73857611, gi\|... - gi\|74314134\|ref\|YP_312553.1\| lipopolysaccharide core biosynthesis protein [Shigella sonnei Ss046], g...	229.0	[0..1]	[331..13]
gi\|3821832 - gi\|3821832\|gb\|AAC69668.1\| WaaQ [Escherichia coli] gi\|38704185 - gi\|38704185\|ref\|NP_312534.2\| RfaQ [Escherichia coli O157:H7] gi\|254795587, gi... - gi\|254795587\|ref\|YP_003080424.1\| lipopolysaccharide core biosynthesis protein [Escherichia coli O157... gi\|75197534 - gi\|75197534\|ref\|ZP_00707604.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli HS] gi\|110617240, gi... - gi\|110807692\|ref\|YP_691212.1\| lipopolysaccharide core biosynthesis protein [Shigella flexneri 5 str.... gi\|75234790 - gi\|75234790\|ref\|ZP_00719093.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli E11001... gi\|75258172 - gi\|75258172\|ref\|ZP_00729620.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli E22] gi\|75514306 - gi\|75514306\|ref\|ZP_00736614.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli 53638] gi\|38704185 - gi\|38704185\|ref\|NP_312534.2\| lipopolysaccharide core biosynthesis protein [Escherichia coli O157:H7 ... gi\|169753066, gi... - gi\|170018138\|ref\|YP_001723092.1\| lipopolysaccharide core biosynthesis protein [Escherichia coli ATCC... gi\|124499139, gi... - gi\|124530498\|ref\|ZP_01701125.1\| lipopolysaccharide heptosyltransferase III, putative [Escherichia co... gi\|83571418 - gi\|83571418\|ref\|ZP_00922858.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Shigella dysenteriae 10... gi\|209921103, gi... - gi\|209921103\|ref\|YP_002295187.1\| lipopolysaccharide core biosynthesis protein [Escherichia coli SE11... gi\|75188390, gi\|... - gi\|75188390\|ref\|ZP_00701657.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli E24377... gi\|195936193 - gi\|195936193\|ref\|ZP_03081575.1\| lipopolysaccharide core biosynthesis protein [Escherichia coli O157:...	229.0	[0..1]	[331..1]
gi\|75179735 - gi\|75179735\|ref\|ZP_00699722.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Shigella boydii BS512]	229.0	[0..1]	[331..1]
gi\|110345465, gi... - gi\|110643873\|ref\|YP_671603.1\| lipopolysaccharide core biosynthesis protein [Escherichia coli 536], g... gi\|75242589 - gi\|75242589\|ref\|ZP_00726333.1\| COG0859: ADP-heptose:LPS heptosyltransferase [Escherichia coli F11]	228.0	[0..1]	[331..1]

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Predicted Domain #1

Region A:
Residues: [1-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYHGDMLLT TPVISTLKQN YPDAKIDMLL YQDTIPILSE NPEINALYGI SNKGAGTFDK  60
   61 IKNVLSLIKT LRANNYDLVI NLTDQWMVAL LVRCLPARMK ISQLYGHRQH GIWKKSFTHL 120
  121 APIHGTHIVE RNLSVLEPLG ITDFYTDTTM SYAEDCWKKM RRELDALGVK DHYVVIQPTA 180
  181 RQIFKCWDND KFSKVIDALQ QRGYQVVLTC GPSADDLACV DEIARGCETK PITGLAGKTR 240
  241 FPELGALIDH AVLFIGVDSA PGHIAAAVKT PVISLFGATD HVFWRPWTEN IIQFWAGNYQ 300
  301 KMPTRHELDR NKKYLSVIPA EDVIAATEKL LPEDAPSADR NAQL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	1pswA
Description:	ADP-heptose LPS heptosyltransferase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lipopolysaccharide heptosyltransferase activity	3.44180421678517	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.04530122157712	bayes_pls_golite062009
catalytic activity	3.02192459767177	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.94500176353224	bayes_pls_golite062009
glycogen phosphorylase activity	2.09116455393465	bayes_pls_golite062009
glucosyltransferase activity	1.8062586862583	bayes_pls_golite062009
transferase activity	1.67770954408305	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	1.63103907245982	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.4199532885636	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.30934991061674	bayes_pls_golite062009
glycogen (starch) synthase activity	0.435616523537281	bayes_pls_golite062009
phosphorylase activity	0.431662083250969	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.27693350081385	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.22009679964126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: