YRC Public Data Repository - Protein Structure Prediction

Protein:	PTFB_ECOLI, PTFB...
Organism:	Escherichia coli
Length:	563 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTFB_ECOLI, PTFB....

Description	E-value	Query Range	Subject Range
gi\|46913198, gi\|... - gi\|54308768\|ref\|YP_129788.1\| PTS system, fructose-specific IIBC component [Photobacterium profundum ...	426.0	[0..1]	[562..1]
gi\|90410488, gi\|... - gi\|90410488\|ref\|ZP_01218504.1\| PTS system, fructose-specific IIBC component [Photobacterium profundu...	420.0	[0..1]	[562..1]
gi\|70734353, gi\|... - gi\|70734353\|ref\|YP_257993.1\| PTS system, fructose-specific IIBC component [Pseudomonas fluorescens P...	419.0	[0..1]	[560..1]
gi\|91225423, gi\|... - gi\|91225423\|ref\|ZP_01260545.1\| PTS system, fructose-specific IIBC component [Vibrio alginolyticus 12...	418.0	[0..1]	[563..1]
gi\|37200906, gi\|... - gi\|37676364\|ref\|NP_936760.1\| phosphotransferase system, fructose-specific IIC component [Vibrio vuln...	418.0	[0..1]	[563..19]
gi\|151938259, gi... - gi\|75857157\|ref\|ZP_00764775.1\| COG1299: Phosphotransferase system, fructose-specific IIC component [...	415.0	[0..1]	[563..1]
gi\|190904561, gi... - gi\|75231494\|ref\|ZP_00717863.1\| COG1299: Phosphotransferase system, fructose-specific IIC component [...	415.0	[0..1]	[563..1]
gi\|71737234, gi\|... - gi\|71737234\|ref\|YP_273130.1\| phosphotransferase system, fructose-specific IIBC component [Pseudomona...	415.0	[0..1]	[562..1]
gi\|27366653, gi\|... - gi\|27366653\|ref\|NP_762180.1\| phosphotransferase system, fructose-specific IIC component [Vibrio vuln...	413.0	[0..1]	[563..1]
gi\|110343969, gi... - gi\|110642377\|ref\|YP_670107.1\| fructose-specific PTS system IIBC component [Escherichia coli 536], gi...	412.0	[0..1]	[563..1]

Back

Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLLIIDAN LGQARAYMAK TLLGAAARKA KLEIIDNPND AEMAIVLGDS IPNDSALNGK  60
   61 NVWLGDISRA VAHPELFLSE AKGHAKPYTA PVAATAPVAA SGP

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.65
Match:	2r48A
Description:	No description for 2r48A was found.

Predicted functions:

Term	Confidence	Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	4.54010324875064	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	3.99547761010823	bayes_pls_golite062009
transporter activity	1.4988202573861	bayes_pls_golite062009
fructose transmembrane transporter activity	1.44706883275634	bayes_pls_golite062009
sugar transmembrane transporter activity	1.42419212784358	bayes_pls_golite062009
transmembrane transporter activity	1.37037739583443	bayes_pls_golite062009
substrate-specific transporter activity	1.09667314414566	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	1.03203265264347	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.970967271330746	bayes_pls_golite062009
active transmembrane transporter activity	0.923880422120514	bayes_pls_golite062009
binding	0.492104885382449	bayes_pls_golite062009
hexose transmembrane transporter activity	0.31395594320375	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.206138523027914	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [104-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRVVAVTACP TGVAHTFMAA EAIETEAKKR GWWVKVETRG SVGAGNAITP EEVAAADLVI  60
   61 VAADIEVDLA KFAGKPMYRT STGLALKKTA QELDKAVAEA TPYEP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.39794
Match:	2r4qA
Description:	No description for 2r4qA was found.

Predicted Domain #3

Region A:
Residues: [209-374]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGKAQTATTE SKKESAGAYR HLLTGVSYML PMVVAGGLCI ALSFAFGIEA FKEPGTLAAA  60
   61 LMQIGGGSAF ALMVPVLAGY IAFSIADRPG LTPGLIGGML AVSTGSGFIG GIIAGFLAGY 120
  121 IAKLISTQLK LPQSMEALKP ILIIPLISSL VVGLAMIYLI GKPVAG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [375-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILEGLTHWLQ TMGTANAVLL GAILGGMMCT DMGGPVNKAA YAFGVGLLST QTYGPMAAIM  60
   61 AAGMVPPLAM GLATMVARRK FDKAQQEGGK AALVLGLCFI SEGAIPFAAR DPMRVLPCCI 120
  121 VGGALTGAIS MAIGAKLMAP HGGLFVLLIP GAITPVLGYL VAIIAGTLVA GLAYAFLKRP 180
  181 EVDAVAKAA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: