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View Structure Prediction Details

Protein: dab-1
Organism: Caenorhabditis elegans
Length: 492 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dab-1.

Description E-value Query
Range
Subject
Range
dab-1 - disabled-like protein status:Confirmed UniProt:Q8I4H0 protein_id:CAB54270.3
309.0 [0..1] [492..1]
gi|187038857, gi... - gi|39587234|emb|CAE57702.1| Hypothetical protein CBG00708 [Caenorhabditis briggsae], gi|187038857|em...
gi|157749763 - gi|157749763|ref|XP_001678595.1| Hypothetical protein CBG00708 [Caenorhabditis briggsae AF16]
269.0 [0..20] [492..86]
gi|116283965 - gi|116283965|gb|AAH50108.1| Numb protein [Mus musculus]
260.0 [0..23] [311..1]
gi|28193240, gi|... - gi|28193240|emb|CAD62362.1| unnamed protein product [Homo sapiens], gi|119601513|gb|EAW81107.1| numb...
252.0 [0..23] [485..1]
gi|73956392 - gi|73956392|ref|XP_852920.1| PREDICTED: similar to Disabled homolog 1 [Canis familiaris]
252.0 [0..35] [479..113]

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Predicted Domain #1
Region A:
Residues: [1-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKSDISVE TANATSGKPN PPSPKSRLAM LKRTKKASNA SSDPFRFQNN GISYKGKLIG  60
   61 EQDVDKARGD AMCAEAMRTA KSIIKAAGAH KTRITLQINI DGIKVLDEKS GAVLHNFPVS 120
  121 RISFIARDSS DARAFGLVYG EPGGKYKFYG IKTAQAADQA VLAIRDMFQV VFEMKKKQIE 180
  181 QVKQQQIQDG GAEISFQSKK EGGVAVADLL DLESELQQIE RGVQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.39794
Match: 1oqnA
Description: Crystal structure of the phosphotyrosine binding domain (PTB) of mouse Disabled 1 (Dab1)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [226-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSTVPTNCDA FGASPFGDPF VDSFNSTATS NGTANMSGTQ VPFGGLQLPQ VQQMQMPMVQ  60
   61 IPQQSHQNWP TSGAGSFDAW GQQQQQQQMH HAHSTPAFGT NGFSDTNPFA SAFNTQARPP 120
  121 PLPTVAPTQY RDPFSVH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [363-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSAIPNSNID WTGTGTTKEN MAPSTNIQQQ QSSLHHASTF ANFGDNKAET WSEKKVTSLE  60
   61 EAFTKLVDMD ALVGGQGIKE TKKNPFEHIL NPPKASLNSM STTCSAAQMA ATQQHTTSSH 120
  121 ADPFGDDFFR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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