YRC Public Data Repository - Protein Structure Prediction

Protein:	PHSC_ECOLI
Organism:	Escherichia coli
Length:	261 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PHSC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|191173442, gi... - gi\|75238772\|ref\|ZP_00722756.1\| hypothetical protein EcolF_01003291 [Escherichia coli F11], gi\|191173... gi\|110343383, gi... - gi\|110641791\|ref\|YP_669521.1\| PhsC-like protein [Escherichia coli 536], gi\|110343383\|gb\|ABG69620.1\| ...	170.0	[0..1]	[261..1]
gi\|227885914, gi... - gi\|227885914\|ref\|ZP_04003719.1\| possible cytochrome [Escherichia coli 83972], gi\|227837093\|gb\|EEJ475... gi\|26247919, gi\|... - gi\|26247919\|ref\|NP_753959.1\| PhsC protein [Escherichia coli CFT073], gi\|26108322\|gb\|AAN80524.1\|AE016...	170.0	[0..1]	[261..1]
gi\|110615194, gi... - gi\|110805646\|ref\|YP_689166.1\| hypothetical protein SFV_1692 [Shigella flexneri 5 str. 8401], gi\|1106...	170.0	[0..1]	[261..1]
gi\|81241294, gi\|... - gi\|82777146\|ref\|YP_403495.1\| hypothetical protein SDY_1898 [Shigella dysenteriae Sd197], gi\|81241294...	170.0	[0..1]	[261..1]
gi\|169754908, gi... - gi\|170019980\|ref\|YP_001724934.1\| cytochrome B561 [Escherichia coli ATCC 8739], gi\|169754908\|gb\|ACA77... gi\|157161135, gi... - gi\|75195747\|ref\|ZP_00705817.1\| hypothetical protein EcolH_01001546 [Escherichia coli HS], gi\|1571611... gi\|124498456, gi... - gi\|124531601\|ref\|ZP_01701812.1\| cytochrome B561 [Escherichia coli B], gi\|124498456\|gb\|EAY45968.1\| cy...	170.0	[0..1]	[261..1]
gi\|30041435, gi\|... - gi\|30063183\|ref\|NP_837354.1\| hypothetical protein S1830 [Shigella flexneri 2a str. 2457T], gi\|300414... gi\|75175199, gi\|... - gi\|75175199\|ref\|ZP_00695517.1\| hypothetical protein SboyB_01004662 [Shigella boydii BS512], gi\|18773... gi\|193071597, gi... - gi\|75214848\|ref\|ZP_00713331.1\| hypothetical protein EcolE1_01004507 [Escherichia coli E110019], gi\|1... gi\|81245373, gi\|... - gi\|82543962\|ref\|YP_407909.1\| hypothetical protein SBO_1462 [Shigella boydii Sb227], gi\|81245373\|gb\|A... gi\|24113058, gi\|... - gi\|24113058\|ref\|NP_707568.1\| hypothetical protein SF1698 [Shigella flexneri 2a str. 301], gi\|2405202...	170.0	[0..1]	[261..1]
gi\|74312005, gi\|... - gi\|74312005\|ref\|YP_310424.1\| hypothetical protein SSON_1486 [Shigella sonnei Ss046], gi\|73855482\|gb\|...	169.0	[0..1]	[261..1]
gi\|13361844, gi\|... - gi\|15831631\|ref\|NP_310404.1\| hypothetical protein ECs2377 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|208818756, gi... - gi\|208818756\|ref\|ZP_03259076.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia... gi\|208817017, gi... - gi\|208817017\|ref\|ZP_03258137.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia... gi\|195940381 - gi\|195940381\|ref\|ZP_03085763.1\| hypothetical protein EscherichcoliO157_28960 [Escherichia coli O157:... gi\|189375373, gi... - gi\|189375373\|gb\|EDU93789.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|217328723, gi... - gi\|217328723\|ref\|ZP_03444804.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia... gi\|209160413, gi... - gi\|209399013\|ref\|YP_002270738.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichi... gi\|13361844, gi\|... - gi\|15831631\|ref\|NP_310404.1\| hypothetical protein ECs2377 [Escherichia coli O157:H7], gi\|13361844\|db... gi\|168765127, gi... - gi\|189365009\|gb\|EDU83425.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|25300105, gi\|... - pir\|\|E85774 hypothetical protein ydhU [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|189354430, gi... - gi\|189354430\|gb\|EDU72849.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|254793287, gi... - gi\|254793287\|ref\|YP_003078124.1\| predicted cytochrome [Escherichia coli O157:H7 str. TW14359], gi\|25... gi\|168752356, gi... - gi\|188013784\|gb\|EDU51906.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|15802082, gi\|... - gi\|15802082\|ref\|NP_288104.1\| hypothetical protein Z2697 [Escherichia coli O157:H7 EDL933], gi\|125156... gi\|189370044, gi... - gi\|189370044\|gb\|EDU88460.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|188998795, gi... - gi\|188998795\|gb\|EDU67781.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|187766875, gi... - gi\|187766875\|gb\|EDU30719.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col... gi\|168771666, gi... - gi\|189359626\|gb\|EDU78045.1\| nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia col...	169.0	[0..1]	[261..1]
gi\|218558539, gi... - gi\|218558539\|ref\|YP_002391452.1\| putative cytochrome b subunit of a reductase [Escherichia coli S88]... gi\|117623851, gi... - gi\|117623851\|ref\|YP_852764.1\| putative cytochrome [Escherichia coli APEC O1], gi\|115512975\|gb\|ABJ010...	168.0	[0..1]	[261..1]
gi\|91072457, gi\|... - gi\|91210883\|ref\|YP_540869.1\| YdhU (PhsC)-like protein [Escherichia coli UTI89], gi\|91072457\|gb\|ABE07... gi\|226900373, gi... - gi\|237705616\|ref\|ZP_04536097.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690...	168.0	[0..1]	[261..1]

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Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPSQHAEQF QSQLANYVPQ FTPEFWPVWL IIAGVLLVGM WLVLGLHALL RARGVKKSAT  60
   61 DHGEKIYLYS KAVRLWHWSN ALLFVLLLAS GLINHFAMVG ATAVKSLVAV HEVCGFLLLA 120
  121 CWLGFVLINA VGDNGHHYRI RRQGWLERAA KQTRFYLFGI MQGEEHPFPA TTQSKFNPLQ 180
  181 QVAYVGVMYG LLPLLLLTGL LCLYPQAVGD VFPGVRYWLL QTHFALAFIS LFFIFGHLYL 240
  241 CTTGRTPHET FKSMVDGYHR H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.045757
Match:	1kqfC
Description:	Formate dehydrogenase N, cytochrome (gamma) subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.663361910631013	bayes_pls_golite062009
oxidoreductase activity	0.17038047578982	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: