YRC Public Data Repository - Protein Structure Prediction

Protein:	NUOI_ECOLI
Organism:	Escherichia coli
Length:	180 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUOI_ECOLI.

Description	E-value	Query Range	Subject Range
NUOI_SALPA - NADH-quinone oxidoreductase subunit I OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=nuoI ... NUOI_SALCH - NADH-quinone oxidoreductase subunit I OS=Salmonella choleraesuis GN=nuoI PE=3 SV=1 NUOI_SALPA - NADH-quinone oxidoreductase subunit I OS=Salmonella paratyphi A GN=nuoI PE=3 SV=1 gi\|29136684, gi\|... - gi\|29141058\|ref\|NP_804400.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica serov... gi\|16761246 - gi\|16761246\|ref\|NP_456863.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica serov... NUOI_SALTI - NADH-quinone oxidoreductase subunit I OS=Salmonella typhi GN=nuoI PE=3 SV=1 NUOI_SALTY - NADH-quinone oxidoreductase subunit I OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720... NUOI_SALCH - NADH-quinone oxidoreductase subunit I OS=Salmonella choleraesuis (strain SC-B67) GN=nuoI PE=3 SV=1 NUOI_SALCH - NADH-quinone oxidoreductase subunit I OS=Salmonella choleraesuis GN=nuoI PE=3 SV=1 NUOI_SALTY - NADH-quinone oxidoreductase subunit I OS=Salmonella typhimurium GN=nuoI PE=3 SV=1 lcl\|NC_016856.1_... - [gene=nuoI] [protein=NADH dehydrogenase subunit I] [protein_id=YP_005238397.1] [location=complement(... NUOI_SALTI - NADH-quinone oxidoreductase subunit I OS=Salmonella typhi GN=nuoI PE=3 SV=1 NUOI_SALTY - NADH-quinone oxidoreductase subunit I OS=Salmonella typhimurium GN=nuoI PE=3 SV=1 gi\|194455580, gi... - gi\|194469216\|ref\|ZP_03075200.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. e... gi\|194713764, gi... - gi\|194738262\|ref\|YP_002115390.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. ... gi\|197249761, gi... - gi\|197249761\|ref\|YP_002147279.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. ... gi\|197263656, gi... - gi\|197263656\|ref\|ZP_03163730.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. e... gi\|168465976, gi... - gi\|195631186\|gb\|EDX49746.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|168817949, gi... - gi\|205345035\|gb\|EDZ31799.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|194446441, gi... - gi\|194446441\|ref\|YP_002041581.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. ... gi\|194410099, gi... - gi\|194451795\|ref\|YP_002046374.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica s... gi\|168229690, gi... - gi\|205335833\|gb\|EDZ22597.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|168237338, gi... - gi\|197289600\|gb\|EDY28963.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|205338317, gi... - gi\|205338317\|gb\|EDZ25081.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|205349680, gi... - gi\|205349680\|gb\|EDZ36311.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|161362315, gi... - gi\|161612951\|ref\|YP_001586916.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica s... gi\|167994669, gi... - gi\|205327493\|gb\|EDZ14257.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. enter... gi\|213427017 - gi\|213427017\|ref\|ZP_03359767.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|213580776 - gi\|213580776\|ref\|ZP_03362602.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|213612295 - gi\|213612295\|ref\|ZP_03370121.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|224583193, gi... - gi\|224583193\|ref\|YP_002636991.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica s... gi\|207857739, gi... - gi\|207857739\|ref\|YP_002244390.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica s... gi\|213028651 - gi\|213028651\|ref\|ZP_03343098.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|213052937 - gi\|213052937\|ref\|ZP_03345815.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|213419033 - gi\|213419033\|ref\|ZP_03352099.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|197361716, gi... - gi\|197361716\|ref\|YP_002141352.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica s... gi\|200386777, gi... - gi\|200386777\|ref\|ZP_03213389.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. e... gi\|204929042, gi... - gi\|204929042\|ref\|ZP_03220185.1\| NADH-quinone oxidoreductase, I subunit [Salmonella enterica subsp. e... gi\|238912400 - gi\|238912400\|ref\|ZP_04656237.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica se... gi\|205353436, gi... - gi\|205353436\|ref\|YP_002227237.1\| NADH dehydrogenase subunit I [Salmonella enterica subsp. enterica s...	163.0	[0..1]	[180..1]
NUOI_SHISS - NADH-quinone oxidoreductase subunit I OS=Shigella sonnei (strain Ss046) GN=nuoI PE=3 SV=1	163.0	[0..1]	[180..1]
NUOI_SHIDS - NADH-quinone oxidoreductase subunit I OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=nuoI PE=3...	162.0	[0..1]	[180..1]
gi\|238788647, gi... - gi\|77975472\|ref\|ZP_00831007.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	160.0	[0..1]	[180..1]
NUOI_YERPS - NADH-quinone oxidoreductase subunit I OS=Yersinia pseudotuberculosis GN=nuoI PE=3 SV=1 gi\|229688198, gi... - gi\|229898650\|ref\|ZP_04513795.1\| NADH:ubiquinone oxidoreductase, chain I [Yersinia pestis biovar Orie... gi\|229701775, gi... - gi\|229895289\|ref\|ZP_04510463.1\| NADH:ubiquinone oxidoreductase, chain I [Yersinia pestis Pestoides A... gi\|229838090, gi... - gi\|229838090\|ref\|ZP_04458249.1\| NADH:ubiquinone oxidoreductase, chain I [Yersinia pestis biovar Orie... NUOI_YERPE - NADH-quinone oxidoreductase subunit I OS=Yersinia pestis GN=nuoI PE=3 SV=1 gi\|45437012, gi\|... - gi\|45442148\|ref\|NP_993687.1\| NADH dehydrogenase subunit I [Yersinia pestis biovar Microtus str. 9100... NUOI_YERPP - NADH-quinone oxidoreductase subunit I OS=Yersinia pestis (strain Pestoides F) GN=nuoI PE=3 SV=1 gi\|22125532, gi\|... - gi\|22125532\|ref\|NP_668955.1\| NADH dehydrogenase subunit I [Yersinia pestis KIM], gi\|21958432\|gb\|AAM8... gi\|115348245, gi... - gi\|218929634\|ref\|YP_002347509.1\| NADH dehydrogenase subunit I [Yersinia pestis CO92], gi\|16122766\|re... NUOI_YERPS - NADH-quinone oxidoreductase subunit I OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=... NUOI_YERPG - NADH-quinone oxidoreductase subunit I OS=Yersinia pestis bv. Antiqua (strain Angola) GN=nuoI PE=3 SV... NUOI_YERP3 - NADH-quinone oxidoreductase subunit I OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)... gi\|89105745, gi\|... - gi\|89105745\|ref\|ZP_01178259.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... NUOI_YERPA - NADH-quinone oxidoreductase subunit I OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=nuoI PE=3 S... NUOI_YERPN - NADH-quinone oxidoreductase subunit I OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=nuoI PE=3 ... gi\|165925636, gi... - gi\|165925636\|ref\|ZP_02221468.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis biovar Orien... gi\|166008508, gi... - gi\|166008508\|ref\|ZP_02229406.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis biovar Antiq... gi\|166205006, gi... - gi\|166213832\|ref\|ZP_02239867.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis biovar Antiq... gi\|167399268, gi... - gi\|167399268\|ref\|ZP_02304792.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis biovar Antiq... gi\|166958850, gi... - gi\|167422344\|ref\|ZP_02314097.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis biovar Orien... gi\|149291959, gi... - gi\|149365546\|ref\|ZP_01887581.1\| NADH Dehydrogenase I chain I [Yersinia pestis CA88-4125], gi\|1492919... gi\|167424548, gi... - gi\|167424548\|ref\|ZP_02316301.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis biovar Media... gi\|167470944 - gi\|167470944\|ref\|ZP_02335648.1\| NADH-quinone oxidoreductase, I subunit [Yersinia pestis FV-1] NUOI_YERPY - NADH-quinone oxidoreductase subunit I OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=... NUOI_YERPB - NADH-quinone oxidoreductase subunit I OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=n...	160.0	[0..1]	[180..1]
gi\|238726086, gi... - gi\|77976407\|ref\|ZP_00831898.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	159.0	[0..1]	[180..1]
gi\|77961188, gi\|... - gi\|77961188\|ref\|ZP_00825032.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	158.0	[0..1]	[180..1]
gi\|238697901, gi... - gi\|238763933\|ref\|ZP_04624890.1\| NADH-quinone oxidoreductase subunit I [Yersinia kristensenii ATCC 33... gi\|77957608, gi\|... - gi\|77957608\|ref\|ZP_00821659.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	158.0	[0..1]	[180..1]
NUOI_PHOLL - NADH-quinone oxidoreductase subunit I OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139... NUOI_PHOLL - NADH-quinone oxidoreductase subunit I OS=Photorhabdus luminescens subsp. laumondii GN=nuoI PE=3 SV=1	157.0	[0..1]	[180..1]
NDS8A_ARATH - NADH dehydrogenase [ubiquinone] iron-sulfur protein 8-A, mitochondrial OS=Arabidopsis thaliana GN=At...	157.0	[0..10]	[149..73]

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Predicted Domain #1

Region A:
Residues: [1-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLKELLVGF GTQVRSIWMI GLHAFAKRET RMYPEEPVYL PPRYRGRIVL TRDPDGEERC  60
   61 VACNLCAVAC PVGCISLQKA ETKDGRWYPE FFRINFSRCI FCGLCEEACP TTAIQLTPDF 120
  121 EMGEYKRQDL VYEKEDLLIS GPGKYPEYNF YRMAGMAIDG KDKGEAENEA KPIDVKSLLP 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	2fug9
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NADH dehydrogenase activity	12.5726198200461	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	11.5379710261128	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	11.4267068380664	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	10.7661444048967	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	10.0573871968611	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	7.6692836424589	bayes_pls_golite062009
metal cluster binding	6.88959428302591	bayes_pls_golite062009
iron-sulfur cluster binding	6.88959428302591	bayes_pls_golite062009
oxidoreductase activity	5.95698221294919	bayes_pls_golite062009
electron carrier activity	5.42600867641421	bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity	5.39944360924751	bayes_pls_golite062009
formate dehydrogenase activity	4.7946737640663	bayes_pls_golite062009
FMN binding	1.64858327046622	bayes_pls_golite062009
binding	0.668971250367847	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009
protein binding	0.283477223088022	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0827182678048914	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: