YRC Public Data Repository - Protein Structure Prediction

Protein:	NUDT14
Organism:	Homo sapiens
Length:	222 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUDT14.

Description	E-value	Query Range	Subject Range
NUD14_MOUSE - Uridine diphosphate glucose pyrophosphatase OS=Mus musculus GN=Nudt14 PE=1 SV=1	3.0E-39	[1..222]	[1..222]
gi\|114655100 - gi\|114655100\|ref\|XP_001141720.1\| PREDICTED: nudix -type motif 14 [Pan troglodytes]	2.0E-37	[1..222]	[1..222]
gi\|109479992, gi... - gi\|27717381\|ref\|XP_216799.1\| PREDICTED: similar to nudix (nucleoside diphosphate linked moiety X)-ty...	3.0E-37	[1..222]	[1..222]
NUD14_BOVIN - Uridine diphosphate glucose pyrophosphatase OS=Bos taurus GN=NUDT14 PE=2 SV=1	2.0E-36	[1..222]	[1..222]
gi\|4314286, gi\|1... - gi\|4314286\|gb\|AAD15563.1\| unknown [Homo sapiens], gi\|119602309\|gb\|EAW81903.1\| nudix (nucleoside diph...	2.0E-36	[1..222]	[69..290]
gi\|29373950 - gi\|29373950\|emb\|CAD62374.1\| UDP-sugar diphosphatase [Sus scrofa]	3.0E-36	[1..222]	[1..222]
gi\|109085043 - gi\|109085043\|ref\|XP_001086418.1\| PREDICTED: similar to nudix -type motif 14 [Macaca mulatta]	2.0E-31	[15..222]	[87..294]
gi\|15643937, gi\|... - gi\|4981730\|gb\|AAD36256.1\|AE001774_13 conserved hypothetical protein [Thermotoga maritima MSB8], gi\|1... gi\|7445034 - pir\|\|H72286 conserved hypothetical protein - Thermotoga maritima (strain MSB8)	2.0E-30	[5..214]	[6..175]
gi\|82498927, gi\|... - gi\|82498927\|ref\|ZP_00884381.1\| ADP-ribose pyrophosphatase, putative [Caldicellulosiruptor saccharoly...	6.0E-30	[5..220]	[6..180]

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Predicted Domain #1

Region A:
Residues: [1-222]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERIEGASVG RCAASPYLRP LTLHYRQNGA QKSWDFMKTH DSVTVLLFNS SRRSLVLVKQ  60
   61 FRPAVYAGEV ERRFPGSLAA VDQDGPRELQ PALPGSAGVT VELCAGLVDQ PGLSLEEVAC 120
  121 KEAWEECGYH LAPSDLRRVA TYWSGVGLTG SRQTMFYTEV TDAQRSGPGG GLVEEGELIE 180
  181 VVHLPLEGAQ AFADDPDIPK TLGVIFGVSW FLSQVAPNLD LQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.0
Match:	1g0sA
Description:	ADP-ribose pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.724329914463007	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: