YRC Public Data Repository - Protein Structure Prediction

Protein:	NTF2_KLULA
Organism:	Kluyveromyces lactis
Length:	125 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTF2_KLULA.

Description	E-value	Query Range	Subject Range
NTF2_CANGA - Nuclear transport factor 2 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / ... NTF2_CANGA - Nuclear transport factor 2 OS=Candida glabrata GN=NTF2 PE=3 SV=1	159.0	[0..1]	[125..1]
gi\|50746525 - gi\|50746525\|ref\|XP_420536.1\| PREDICTED: similar to KIAA0660 protein [Gallus gallus]	159.0	[0..3]	[123..92]
gi\|68354696 - gi\|68354696\|ref\|XP_706805.1\| PREDICTED: similar to Ras-GTPase activating protein SH3 domain-binding ...	157.0	[0..3]	[123..6]
gi\|89267900, gi\|... - gi\|89267900\|emb\|CAJ83275.1\| Ras-GTPase activating protein SH3 domain-binding protein 2 (G3BP2) [Xeno...	157.0	[0..3]	[123..6]
gi\|49903639, gi\|... - gi\|49903639\|gb\|AAH76729.1\| MGC81268 protein [Xenopus laevis], gi\|148236557\|ref\|NP_001086506.1\| MGC81...	157.0	[0..3]	[123..6]
NTF2_ASHGO - Nuclear transport factor 2 OS=Ashbya gossypii GN=NTF2 PE=3 SV=1 NTF2_ASHGO - Nuclear transport factor 2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1...	157.0	[0..1]	[125..1]
gi\|125562321 - gi\|125562321\|gb\|EAZ07769.1\| hypothetical protein OsI_30022 [Oryza sativa Indica Group] NTF2_ORYSA - Nuclear transport factor 2 (NTF-2) - Oryza sativa (Rice) NTF2_ORYSJ - Nuclear transport factor 2 OS=Oryza sativa subsp. japonica GN=NTF2 PE=2 SV=1	157.0	[0..3]	[123..1]
ORFP:6054 - YER009W, Contig c425 25784-26161 gi\|190405570 - gi\|190405570\|gb\|EDV08837.1\| nuclear transport factor [Saccharomyces cerevisiae RM11-1a] NTF2_YEAST - Nuclear transport factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTF2 PE=1 SV=... NTF2 - Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to tr... gi\|151944717 - gi\|151944717\|gb\|EDN62976.1\| nuclear transport factor [Saccharomyces cerevisiae YJM789]	156.0	[0..1]	[125..1]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVDFSSLAQ QFTEFYYNQF DSDRTQLGNL YREQSMLTFE TTQLQGAKDI VEKLVSLPFQ  60
   61 KVAHRITTLD AQPASPNGDV LVMITGDLLI DEEQNPQRFS QVFHLMPEGS SYYVYNDIFR 120
  121 LNYSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.09691
Match:	1gy7A
Description:	Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.2858716221712	bayes_pls_golite062009
nucleocytoplasmic transporter activity	2.57260151088345	bayes_pls_golite062009
binding	2.32562999055027	bayes_pls_golite062009
protein transmembrane transporter activity	2.22367856601071	bayes_pls_golite062009
transporter activity	1.80701285041353	bayes_pls_golite062009
substrate-specific transporter activity	1.33804818542017	bayes_pls_golite062009
structural constituent of nuclear pore	1.30758304562723	bayes_pls_golite062009
protein binding	1.24260899146543	bayes_pls_golite062009
transmembrane transporter activity	1.22102896992563	bayes_pls_golite062009
Ran GTPase binding	1.18290069522408	bayes_pls_golite062009
RNA binding	1.05240446104847	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.890150150408175	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.79772386064313	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.79772386064313	bayes_pls_golite062009
nucleic acid binding	0.688410645367506	bayes_pls_golite062009
primary active transmembrane transporter activity	0.446562877324676	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.439519001457896	bayes_pls_golite062009
active transmembrane transporter activity	0.430285640125175	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: