YRC Public Data Repository - Protein Structure Prediction

Protein:	NTF2_DAVTA
Organism:	Davidiella tassiana
Length:	125 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NTF2_DAVTA.

Description	E-value	Query Range	Subject Range
NTF2_CANGA - Nuclear transport factor 2 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / ... NTF2_CANGA - Nuclear transport factor 2 OS=Candida glabrata GN=NTF2 PE=3 SV=1	153.0	[0..3]	[124..4]
gi\|223640932, gi... - gi\|241949743\|ref\|XP_002417594.1\| nuclear transport factor 2, putative [Candida dubliniensis CD36], g... NTF2_CANAX - Nuclear transport factor 2 OS=Candida albicans GN=NTF2 PE=3 SV=1	152.0	[0..3]	[123..4]
ORFP:6054 - YER009W, Contig c425 25784-26161 gi\|190405570 - gi\|190405570\|gb\|EDV08837.1\| nuclear transport factor [Saccharomyces cerevisiae RM11-1a] NTF2_YEAST - Nuclear transport factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NTF2 PE=1 SV=... NTF2 - Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to tr... gi\|151944717 - gi\|151944717\|gb\|EDN62976.1\| nuclear transport factor [Saccharomyces cerevisiae YJM789]	151.0	[0..3]	[124..4]
NTF2_EMENI - Nuclear transport factor 2 OS=Emericella nidulans GN=ntf2 PE=3 SV=1 NTF2_EMENI - Nuclear transport factor 2 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 1...	151.0	[0..1]	[124..1]
NTF2_DEBHA - Nuclear transport factor 2 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0... NTF2_DEBHA - Nuclear transport factor 2 OS=Debaryomyces hansenii GN=NTF2 PE=3 SV=1	151.0	[0..3]	[123..4]
NTF2_ASHGO - Nuclear transport factor 2 OS=Ashbya gossypii GN=NTF2 PE=3 SV=1 NTF2_ASHGO - Nuclear transport factor 2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1...	151.0	[0..3]	[124..4]
gi\|119491835, gi... - gi\|119491835\|ref\|XP_001263412.1\| nuclear transport factor NTF-2, putative [Neosartorya fischeri NRRL... gi\|70999712, gi\|... - gi\|70999712\|ref\|XP_754573.1\| nuclear transport factor NTF-2 [Aspergillus fumigatus Af293], gi\|668522... gi\|159127586 - gi\|159127586\|gb\|EDP52701.1\| nuclear transport factor NTF-2, putative [Aspergillus fumigatus A1163]	151.0	[0..1]	[124..1]
NTF2_KLULA - Nuclear transport factor 2 OS=Kluyveromyces lactis GN=NTF2 PE=3 SV=1 NTF2_KLULA - Nuclear transport factor 2 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1...	150.0	[0..3]	[124..4]
gi\|119187145, gi... - gi\|90302965\|gb\|EAS32596.1\| hypothetical protein CIMG_03620 [Coccidioides immitis RS], gi\|119187145\|r... gi\|240108306 - gi\|240108306\|gb\|EER26480.1\| Nuclear transport factor 2 , putative [Coccidioides posadasii C735 delta...	149.0	[0..1]	[123..1]
NTF2_SCHPO - Nuclear transport factor 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ntf2 PE=3 SV=2 nxt2 - nuclear transport factor Nxt2	149.0	[0..1]	[122..1]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDFNAIAQQ FTEFYYKTFD TDRAQLAPLY RENSMLTFEQ SPFLGTANIV GKLQELPFQR  60
   61 IEHQVATVDA QPSNESGGIL VVVSGALLVE EERRPMSYTQ TFQLLPADGA YYVFNDVFRL 120
  121 VYPAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.39794
Match:	1gy7A
Description:	Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	3.2858716221712	bayes_pls_golite062009
nucleocytoplasmic transporter activity	2.57260151088345	bayes_pls_golite062009
binding	2.32562999055027	bayes_pls_golite062009
protein transmembrane transporter activity	2.22367856601071	bayes_pls_golite062009
transporter activity	1.80701285041353	bayes_pls_golite062009
substrate-specific transporter activity	1.33804818542017	bayes_pls_golite062009
structural constituent of nuclear pore	1.30758304562723	bayes_pls_golite062009
protein binding	1.24260899146543	bayes_pls_golite062009
transmembrane transporter activity	1.22102896992563	bayes_pls_golite062009
Ran GTPase binding	1.18290069522408	bayes_pls_golite062009
RNA binding	1.05240446104847	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.890150150408175	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.79772386064313	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.79772386064313	bayes_pls_golite062009
nucleic acid binding	0.688410645367506	bayes_pls_golite062009
primary active transmembrane transporter activity	0.446562877324676	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.439519001457896	bayes_pls_golite062009
active transmembrane transporter activity	0.430285640125175	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: