YRC Public Data Repository - Protein Structure Prediction

Protein:	NPC2_DANRE
Organism:	Danio rerio
Length:	149 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NPC2_DANRE.

Description	E-value	Query Range	Subject Range
NPC2_BOVIN - Epididymal secretory protein E1 OS=Bos taurus GN=NPC2 PE=1 SV=1	177.0	[0..1]	[147..1]
gi\|74212648 - gi\|74212648\|dbj\|BAE31061.1\| unnamed protein product [Mus musculus]	171.0	[0..1]	[149..1]
gi\|62896507 - gi\|62896507\|dbj\|BAD96194.1\| Niemann-Pick disease, type C2 precursor variant [Homo sapiens]	165.0	[0..14]	[149..14]
gi\|27465565, gi\|... - gi\|34786047\|gb\|AAH58132.1\| Niemann-Pick disease, type C2 [Rattus norvegicus], gi\|27465565\|ref\|NP_775...	164.0	[0..1]	[147..1]
gi\|148234356, gi... - gi\|46249888\|gb\|AAH68868.1\| MGC82279 protein [Xenopus laevis], gi\|148234356\|ref\|NP_001084605.1\| hypot...	159.0	[0..4]	[149..5]
gi\|51947564 - gi\|51947564\|gb\|AAU14264.1\| GekBS056P [Gekko japonicus]	158.0	[0..2]	[148..1]

Back

Predicted Domain #1

Region A:
Residues: [1-149]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYRVLGVVL LSFLAYTCAD PVKFVDCGSV DGKVVQVDIK PCSQQPCKLH KGQSYTVNVT  60
   61 FSSGVESQTS KAVVHGVLAG VPVPFPIPID DGCKSGIQCP IVPQKPYNYV TELPVKTEYP 120
  121 AIKVVVEWEL RDDSSKDLFC IKFPVQIVN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1nepA
Description:	Epididymal secretory protein E1 (Niemann-Pick C2 protein)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits