YRC Public Data Repository - Protein Structure Prediction

Protein:	NLPI_ECOLI
Organism:	Escherichia coli
Length:	294 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NLPI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	256.0	[0..4]	[293..1041]
gi\|76659287 - gi\|76659287\|ref\|XP_885188.1\| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 13 ...	243.0	[0..3]	[294..79]
gi\|72002781, gi\|... - gi\|72382931\|ref\|YP_292286.1\| TPR repeat-containing protein [Prochlorococcus marinus str. NATL2A], gi...	243.0	[0..3]	[293..105]
gi\|40063047 - gi\|40063047\|gb\|AAR37903.1\| TPR domain/sulfotransferase domain protein [uncultured marine bacterium 5...	241.0	[0..3]	[292..92]
gi\|18250916, gi\|... - gi\|6911265\|gb\|AAF31458.1\| HRNT1 [Homo sapiens], gi\|2266994\|gb\|AAB63466.1\| O-linked GlcNAc transferas...	241.0	[0..3]	[294..78]
gi\|91204151 - gi\|91204151\|emb\|CAJ71804.1\| conserved hypothetical tpr repeat protein [Candidatus Kuenenia stuttgart...	241.0	[0..2]	[293..465]
gi\|56967372, gi\|... - gi\|62821820\|ref\|NP_001017359.1\| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...	240.0	[0..9]	[293..142]

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Predicted Domain #1

Region A:
Residues: [1-294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPFLRWCFV ATALTLAGCS NTSWRKSEVL AVPLQPTLQQ EVILARMEQI LASRALTDDE  60
   61 RAQLLYERGV LYDSLGLRAL ARNDFSQALA IRPDMPEVFN YLGIYLTQAG NFDAAYEAFD 120
  121 SVLELDPTYN YAHLNRGIAL YYGGRDKLAQ DDLLAFYQDD PNDPFRSLWL YLAEQKLDEK 180
  181 QAKEVLKQHF EKSDKEQWGW NIVEFYLGNI SEQTLMERLK ADATDNTSLA EHLSETNFYL 240
  241 GKYYLSLGDL DSATALFKLA VANNVHNFVE HRYALLELSL LGQDQDDLAE SDQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.39794
Match:	1xnfA
Description:	Crystal structure of E.coli TPR-protein NlpI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.0016189620256075	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: