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View Structure Prediction Details

Protein: NEPU2_THEVU
Organism: Thermoactinomyces vulgaris
Length: 585 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEPU2_THEVU.

Description E-value Query
Range
Subject
Range
gi|21465703, gi|... - gi|21465703|pdb|1JF6|B Chain B, Crystal Structure Of Thermoactinomyces Vulgaris R-47 Alpha- Amylase ...
499.0 [0..1] [585..1]
gi|56419238, gi|... - gi|56419238|ref|YP_146556.1| alpha-cyclodextrinase [Geobacillus kaustophilus HTA426], gi|56379080|db...
489.0 [0..1] [584..1]

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Predicted Domain #1
Region A:
Residues: [1-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLEAIFHEA KGSYAYPISE TQLRVRLRAK KGDVVRCEVL YADRYASPEE ELAHALAGKA  60
   61 GSDERFDYFE ALLECSTKRV KYVFLLTGPQ GEAVYFGETG FSAERSKAGV FQYAYIHRSE 120
  121 VFTTPEWAKE AVIYQIFPER FANGDPSNDP PGTEQWAKDA RPRHDSFYGG DLKGVIDRLP 180
  181 YLEELGVTAL YFTPIFASPS HHKYDTADYL AIDPQFGDLP TFRRLVDEAH RRGIKIILDA 240
  241 VFNHAGDQFF AFRDVLQKGE QSRYKDWFFI EDFPVSKTSR TNYETFAVQV PAMPKLRTEN 300
  301 PEVKEYLFDV ARFWMEQGID GWRLDVANEV DHAFWREFRR LVKSLNPDAL IVGEIWHDAS 360
  361 GWLMGDQFDS VMNYLFRESV IRFFATGEIH AERFDAELTR ARMLYPEQAA QGLWNLLDSH 420
  421 DTERFLTSCG GNEAKFRLAV LFQMTYLGTP LIYYGDEIGM AGATDPDCRR PMIWEEKEQN 480
  481 RGLFEFYKEL IRLRHRLASL TRGNVRSWHA DKQANLYAFV RTVQDQHVGV VLNNRGEKQT 540
  541 VLLQVPESGG KTWLDCLTGE EVHGKQGQLK LTLRPYQGMI LWNGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 142.0
Match: 1jf6A
Description: Maltogenic amylase, N-terminal domain N; Maltogenic amylase; Maltogenic amylase, central domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity, hydrolyzing O-glycosyl compounds 4.55801959095491 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 4.29108420555514 bayes_pls_golite062009
hydrolase activity 2.98140830993539 bayes_pls_golite062009
trehalase activity 2.11042620996316 bayes_pls_golite062009
alpha-amylase activity 2.09193270404736 bayes_pls_golite062009
amylase activity 2.03484942782894 bayes_pls_golite062009
chitinase activity 1.947859226275 bayes_pls_golite062009
glucosidase activity 1.92306554001182 bayes_pls_golite062009
catalytic activity 1.85569074294201 bayes_pls_golite062009
hexosaminidase activity 0.763360027922833 bayes_pls_golite062009
binding 0.63693798355947 bayes_pls_golite062009
alpha-glucosidase activity 0.502835520523619 bayes_pls_golite062009
maltase activity 0.442635030512661 bayes_pls_golite062009
carbohydrate binding 0.28185708488534 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.266938437560648 bayes_pls_golite062009
beta-N-acetylhexosaminidase activity 0.263065978664289 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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