YRC Public Data Repository - Protein Structure Prediction

Protein:	NARY_ECOLI
Organism:	Escherichia coli
Length:	514 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NARY_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194444066, gi... - gi\|194444066\|ref\|YP_002041013.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enter... gi\|168820499, gi... - gi\|205342633\|gb\|EDZ29397.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enterica s... gi\|168462763, gi... - gi\|195634215\|gb\|EDX52567.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enterica s... gi\|168260015, gi... - gi\|205350919\|gb\|EDZ37550.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enterica s... gi\|204927543, gi... - gi\|204927543\|ref\|ZP_03218744.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enteri... gi\|197362240, gi... - gi\|197362240\|ref\|YP_002141877.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica sub... gi\|197213029, gi... - gi\|197249326\|ref\|YP_002146267.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enter... gi\|194456011, gi... - gi\|194469647\|ref\|ZP_03075631.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enteri... gi\|25285394, gi\|... - gi\|25285394\|pir\|\|AI0648 respiratory nitrate reductase 1 beta chain [imported] - Salmonella enterica ... gi\|29142106, gi\|... - gi\|29142106\|ref\|NP_805448.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica subsp. ... gi\|205332155, gi... - gi\|205332155\|gb\|EDZ18919.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enterica s... gi\|161613745, gi... - gi\|161613745\|ref\|YP_001587710.1\| hypothetical protein SPAB_01470 [Salmonella enterica subsp. enteric... gi\|16760123 - gi\|16760123\|ref\|NP_455740.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica subsp. ... gi\|56413315, gi\|... - gi\|56413315\|ref\|YP_150390.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica subsp. ... gi\|213864730 - gi\|213864730\|ref\|ZP_03386849.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica subs... gi\|213650211 - gi\|213650211\|ref\|ZP_03380264.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica subs... gi\|213428331 - gi\|213428331\|ref\|ZP_03361081.1\| respiratory nitrate reductase 1 beta chain [Salmonella enterica subs...	604.0	[0..1]	[511..1]
gi\|192929074, gi... - gi\|75257735\|ref\|ZP_00729220.1\| COG1140: Nitrate reductase beta subunit [Escherichia coli E22], gi\|19... gi\|75239912, gi\|... - gi\|75239912\|ref\|ZP_00723873.1\| COG1140: Nitrate reductase beta subunit [Escherichia coli E110019], g... gi\|194416073, gi... - gi\|75212840\|ref\|ZP_00712838.1\| COG1140: Nitrate reductase beta subunit [Escherichia coli B171], gi\|1... gi\|157081095, gi... - gi\|75190511\|ref\|ZP_00703778.1\| COG1140: Nitrate reductase beta subunit [Escherichia coli E24377A], g...	604.0	[0..1]	[514..1]
gi\|194450438, gi... - gi\|194450438\|ref\|YP_002045806.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enter... gi\|197265719, gi... - gi\|197265719\|ref\|ZP_03165793.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enteri... lcl\|NC_016856.1_... - [gene=narH] [protein=nitrate reductase 1 subunit beta] [protein_id=YP_005237690.1] [location=complem... gi\|205339556, gi... - gi\|205339556\|gb\|EDZ26320.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enterica s... gi\|16765104, gi\|... - gi\|16765104\|ref\|NP_460719.1\| nitrate reductase 1 beta subunit [Salmonella typhimurium LT2], gi\|16420...	604.0	[0..1]	[511..1]
gi\|191165116, gi... - gi\|75231779\|ref\|ZP_00718120.1\| COG1140: Nitrate reductase beta subunit [Escherichia coli B7A], gi\|19...	604.0	[0..1]	[514..1]
gi\|83587807, gi\|... - gi\|83587807\|ref\|ZP_00926433.1\| COG1140: Nitrate reductase beta subunit [Escherichia coli 101-1], gi\|... gi\|242377220, gi... - gi\|251784947\|ref\|YP_002999251.1\| hypothetical protein B21_01437 [Escherichia coli BL21], gi\|24237722... gi\|254161525, gi... - gi\|254161525\|ref\|YP_003044633.1\| nitrate reductase 2 (NRZ), beta subunit [Escherichia coli B str. RE... gi\|253324604, gi... - gi\|254288330\|ref\|YP_003054078.1\| nitrate reductase 2 (NRZ), beta subunit [Escherichia coli BL21(DE3)...	604.0	[0..1]	[514..1]
gi\|91072282, gi\|... - gi\|91210708\|ref\|YP_540694.1\| cryptic nitrate reductase 2, beta subunit [Escherichia coli UTI89], gi\|... gi\|237705447, gi... - gi\|237705447\|ref\|ZP_04535928.1\| cryptic nitrate reductase 2 [Escherichia sp. 3_2_53FAA], gi\|22690020... gi\|117623705, gi... - gi\|117623705\|ref\|YP_852618.1\| cryptic nitrate reductase 2, beta subunit [Escherichia coli APEC O1], ... gi\|170521210, gi... - gi\|170683492\|ref\|YP_001743761.1\| nitrate reductase 2, beta subunit [Escherichia coli SMS-3-5], gi\|17... gi\|218558392, gi... - gi\|218558392\|ref\|YP_002391305.1\| nitrate reductase 2 (NRZ), beta subunit [Escherichia coli S88], gi\|... gi\|218700097, gi... - gi\|218700097\|ref\|YP_002407726.1\| nitrate reductase 2 (NRZ), beta subunit [Escherichia coli IAI39], g...	604.0	[0..1]	[514..1]
gi\|62127960, gi\|... - gi\|62180327\|ref\|YP_216744.1\| nitrate reductase 1, FeS (beta) subunit [Salmonella enterica subsp. ent... gi\|167553935, gi... - gi\|205321759\|gb\|EDZ09598.1\| nitrate reductase 1, beta subunit [Salmonella enterica subsp. enterica s...	603.0	[0..1]	[511..1]
gi\|227836896, gi... - gi\|227886139\|ref\|ZP_04003944.1\| respiratory nitrate reductase 2 beta chain [Escherichia coli 83972],... gi\|26108159, gi\|... - gi\|26247757\|ref\|NP_753797.1\| respiratory nitrate reductase 2 beta chain [Escherichia coli CFT073], g...	603.0	[0..1]	[514..1]
gi\|74312168, gi\|... - gi\|74312168\|ref\|YP_310587.1\| cryptic nitrate reductase 2, beta subunit [Shigella sonnei Ss046], gi\|7...	602.0	[0..1]	[514..1]
gi\|197093876, gi... - gi\|197362399\|ref\|YP_002142036.1\| respiratory nitrate reductase 2 beta chain [Salmonella enterica sub... gi\|56127732, gi\|... - gi\|56413475\|ref\|YP_150550.1\| respiratory nitrate reductase 2 beta chain [Salmonella enterica subsp. ...	602.0	[0..1]	[514..1]

Back

Predicted Domain #1

Region A:
Residues: [1-514]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIRSQVGMV LNLDKCIGCH TCSVTCKNVW TGREGMEYAW FNNVETKPGI GYPKNWEDQE  60
   61 EWQGGWVRDV NGKIRPRLGN KMGVITKIFA NPVVPQIDDY YEPFTFDYEH LHSAPEGKHI 120
  121 PTARPRSLID GKRMDKVIWG PNWEELLGGE FEKRARDRNF EAMQKEMYGQ FENTFMMYLP 180
  181 RLCEHCLNPS CVATCPSGAI YKREEDGIVL IDQDKCRGWR LCISGCPYKK IYFNWKSGKS 240
  241 EKCIFCYPRI ESGQPTVCSE TCVGRIRYLG VLLYDADRIE EAASTEREVD LYERQCEVFL 300
  301 DPHDPSVIEE ALKQGIPQNV IDAAQRSPVY KMAMDWKLAL PLHPEYRTLP MVWYVPPLSP 360
  361 IQSYADAGGL PKSEGVLPAI ESLRIPVQYL ANMLSAGDTG PVLRALKRMM AMRHYMRSQT 420
  421 VEGVTDTRAI DEVGLSVAQV EEMYRYLAIA NYEDRFVIPT SHREMAGDAF AERNGCGFTF 480
  481 GDGCHGSDSK FNLFNSSRID AINITEVRDK AEGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	171.0
Match:	1q16B
Description:	Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nitrate reductase activity	5.37863699545988	bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors	4.93893088248019	bayes_pls_golite062009
NADH dehydrogenase activity	4.88743394067551	bayes_pls_golite062009
formate dehydrogenase activity	4.7946737640663	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	4.55719216073898	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	4.48458992978765	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	3.86485405159262	bayes_pls_golite062009
electron carrier activity	3.21957528314564	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	2.62563452171293	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	1.955968643763	bayes_pls_golite062009
oxidoreductase activity	1.70629793236166	bayes_pls_golite062009
iron-sulfur cluster binding	1.30496569995148	bayes_pls_golite062009
metal cluster binding	1.30496569995148	bayes_pls_golite062009
binding	0.690970987880597	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009
protein binding	0.429260499627782	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0827182678048914	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: