YRC Public Data Repository - Protein Structure Prediction

Protein:	NADC_PSEAE
Organism:	Pseudomonas aeruginosa
Length:	282 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NADC_PSEAE.

Description	E-value	Query Range	Subject Range
gi\|126198042, gi... - gi\|84322942\|ref\|ZP_00971019.1\| COG0157: Nicotinate-nucleotide pyrophosphorylase [Pseudomonas aerugin...	7.0E-86	[1..282]	[1..282]
gi\|84317148, gi\|... - gi\|84317148\|ref\|ZP_00965604.1\| COG0157: Nicotinate-nucleotide pyrophosphorylase [Pseudomonas aerugin...	1.0E-85	[1..282]	[1..282]
gi\|32039744, gi\|... - gi\|32039744\|ref\|ZP_00138016.1\| COG0157: Nicotinate-nucleotide pyrophosphorylase [Pseudomonas aerugin...	1.0E-85	[1..282]	[1..282]
gi\|77381015, gi\|... - gi\|77457012\|ref\|YP_346517.1\| nicotinate-nucleotide pyrophosphorylase [Pseudomonas fluorescens Pf0-1]...	9.0E-85	[1..282]	[1..282]
gi\|150960287, gi... - gi\|94416197\|ref\|ZP_01296027.1\| hypothetical protein PaerP_01002040 [Pseudomonas aeruginosa PA7], gi\|...	1.0E-84	[1..282]	[1..282]
gi\|49083267 - gi\|49083267\|gb\|AAT50988.1\| PA4524 [synthetic construct]	1.0E-84	[1..282]	[1..282]
gi\|37199711, gi\|... - gi\|37680961\|ref\|NP_935570.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus YJ016], gi\|371...	7.0E-84	[8..280]	[29..306]
gi\|91228624, gi\|... - gi\|91228624\|ref\|ZP_01262541.1\| nicotinate-nucleotide pyrophosphorylase [Vibrio alginolyticus 12G01],...	9.0E-84	[8..280]	[17..294]
gi\|16930777 - gi\|16930777\|gb\|AAL32048.1\|AF439854_1 NadC [Vibrio vulnificus]	2.0E-83	[8..280]	[17..294]
gi\|71734451, gi\|... - gi\|71734451\|ref\|YP_273122.1\| nicotinate-nucleotide pyrophosphorylase [Pseudomonas syringae pv. phase...	3.0E-83	[1..282]	[1..282]

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Predicted Domain #1

Region A:
Residues: [1-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNLTLADLQ GEIQANVRTA LAEDVGGGDL TAQLIDPQRE AEARVITREH ATIAGRAWVD  60
   61 EVFRQVDPRV LVTWQVEDGQ RVEPNQMLFQ LKGPARALLT GERSALNFLQ LLSGTATRSQ 120
  121 HYADLVAGTA VKLLDTRKTL PGLRLAQKYA VTCGGCHNHR IGLYDAFLIK ENHIAACGGI 180
  181 DRAIAEARRI APGKPVEVEV ENLDELRQAL EAGADIVMLD ELSLDDMRTA VALTAGRAKL 240
  241 EASGGINEGT LRNIAETGVD YISIGTLTKD VRAVDLSMRL TL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.154902
Match:	1qapA
Description:	Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate phosphoribosyltransferase activity	3.4096751090496	bayes_pls_golite062009
nicotinate-nucleotide diphosphorylase (carboxylating) activity	3.12788282156037	bayes_pls_golite062009
binding	1.58263447797054	bayes_pls_golite062009
catalytic activity	0.60409960326459	bayes_pls_golite062009
protein binding	0.502035039039958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: