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View Structure Prediction Details

Protein: pde-6
Organism: Caenorhabditis elegans
Length: 697 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for pde-6.

Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDRSGVGGE EGEKSVLGAS AHSQAGRRQQ HTPAARRGAQ RAPAATAAAA SRPVFAMRWC  60
   61 CGGSYSENGG GGGGSRGAPP TPLLTVAATS SSTAHDTFG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [100-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMQVKMLKTA VIVTEGTGES VLLDSLRASG WICTVSFPTQ ATSDVESICP LAVFIDLRVP  60
   61 HPSQIAKDVS SVSTEEVLIV SIAEKHISEK RRRALAQSNI IHHVTWNTRD VVLFDYVGRL 120
  121 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 1mvoA
Description: PhoP receiver domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [221-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRIRALPALF AVLDETDQAV EICDEQRVVQ YVNRAYENVT GCIRSEVIGQ PESEMRRKSL  60
   61 PRARGEEERR RSCDWKFIRV PFANNSQFVY MKRSNTTGDT AAIFRDVSLK SLKSQTGGIE 120
  121 APISEVLTM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.39794
Match: 2gj3A
Description: No description for 2gj3A was found.

Predicted Domain #4
Region A:
Residues: [350-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRDVSARVDG EPAQTIKDAM KVLSSHELYA PSINRFRDAD RIATQYYDGL IRLHHPARQR  60
   61 KRSVVDAHRE KRGSHGERRR VSADVKNALE N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [441-697]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNCWKFDILH LEKVSDHHAL SQVGMKVFER WKVCDVLGCS DDLLHRWILS IEAHYHAGNT  60
   61 YHNATHAADV LQATSFFLDS PSVAVHVNES HAVAALLAAA VHDLDHPGRG NAYLINTRQS 120
  121 LAILYNDNSI LENHHIALAF QLTLQHNANV NIFSSLSREE FIQMRHAMVE MVLATDISRH 180
  181 FEYLAKFNKM HVTDVPEEQR DTNSLTICDM LVKCADISNP AREWGLCQRW AHRIVEEYFE 240
  241 QVRRSGEGGN CRFAGNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.0
Match: 1oynA
Description: Catalytic domain of cyclic nucleotide phosphodiesterase pde4d
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle