YRC Public Data Repository - Protein Structure Prediction

Protein:	MURA_YERPE
Organism:	Yersinia pestis
Length:	420 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MURA_YERPE.

Description	E-value	Query Range	Subject Range
gi\|45443555, gi\|... - gi\|45443555\|ref\|NP_995094.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Yersinia pestis biov...	0.0	[1..420]	[4..423]
MURA_ENTCL - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Enterobacter cloacae GN=murA PE=1 SV=1 MURA_ENTCC - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Enterobacter cloacae subsp. cloacae (strain ATC...	0.0	[1..420]	[1..419]
gi\|77977076, gi\|... - gi\|77977076\|ref\|ZP_00832536.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Yersinia in...	0.0	[1..420]	[1..421]
MURA_ERWCT - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Erwinia carotovora subsp. atroseptica GN=murA P... MURA_PECAS - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Pectobacterium atrosepticum (strain SCRI 1043 /...	0.0	[1..419]	[1..418]
gi\|238796195, gi... - gi\|77963487\|ref\|ZP_00827296.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Yersinia mo...	0.0	[1..420]	[1..421]
MURA_ECO57 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O157:H7 GN=murA PE=3 SV=1 gi\|208735721, gi... - gi\|208814444\|ref\|ZP_03255773.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... gi\|208739375, gi... - gi\|208819252\|ref\|ZP_03259572.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... MURA_ECO5E - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC)... gi\|217319478, gi... - gi\|217327111\|ref\|ZP_03443194.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... gi\|168781333, gi... - gi\|189000969\|gb\|EDU69955.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O157... gi\|189373783, gi... - gi\|189373783\|gb\|EDU92199.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O157... gi\|195940045 - gi\|195940045\|ref\|ZP_03085427.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... gi\|208728567, gi... - gi\|208808766\|ref\|ZP_03251103.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... gi\|188014361, gi... - gi\|188014361\|gb\|EDU52483.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O157... gi\|168754171, gi... - gi\|189358394\|gb\|EDU76813.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O157... gi\|189361807, gi... - gi\|189361807\|gb\|EDU80226.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O157... gi\|15803729, gi\|... - gi\|15803729\|ref\|NP_289763.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O15... gi\|209758150, gi... - pir\|\|G85982 UDP-N-glucosamine 1-carboxyvinyltransferase [imported] - Escherichia coli (strain O157:H... gi\|13363541, gi\|... - gi\|15833322\|ref\|NP_312095.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli O15... gi\|254594538, gi... - gi\|254795138\|ref\|YP_003079975.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli...	0.0	[1..420]	[1..419]
MURA_ECOLI - UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) (Enoylpyruvate transferase) (UDP-N-ac... MURA_ECOL6 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O6 GN=murA PE=3 SV=1 MURA_ECOLC - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 /... MURA_SHIFL - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Shigella flexneri GN=murA PE=3 SV=1 MURA_ECOSM - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=mu... gi\|194434473, gi... - gi\|194434473\|ref\|ZP_03066733.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Shigella dysenter... EG11358 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase / UDP-N-acetylglucosamine enoylpyruvyl transferase... sp\|B7UJS9\|MURA_ECO27 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPE... gi\|192926975, gi... - gi\|75256565\|ref\|ZP_00728195.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... MURA_ECOSE - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli (strain SE11) GN=murA PE=3 SV=... gi\|192956396, gi... - gi\|75234897\|ref\|ZP_00719188.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... MURA_ECO27 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPE... gi\|190905237, gi... - gi\|75236230\|ref\|ZP_00720340.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... MURA_ECO8A - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O8 (strain IAI1) GN=murA PE=3 ... gi\|191168625, gi... - gi\|75228150\|ref\|ZP_00714815.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... MURA_ECO45 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN... MURA_ECOUT - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli (strain UTI89 / UPEC) GN=murA ... MURA_ECOK1 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O1:K1 / APEC GN=murA PE=3 SV=1 MURA_ECO81 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O81 (strain ED1a) GN=murA PE=3... gi\|89109952, gi\|... - gi\|89109952\|ref\|AP_003732.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli str... MURA_ECOL5 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC)... gi\|124528469, gi... - gi\|124528469\|ref\|ZP_01699758.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... MURA_ECO55 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=murA ... MURA_SHISS - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Shigella sonnei (strain Ss046) GN=murA PE=3 SV=... MURA_SHIF8 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Shigella flexneri serotype 5b (strain 8401) GN=... MURA_ECO7I - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) G... gi\|188495987, gi... - gi\|75511908\|ref\|ZP_00734520.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... MURA_ECOLU - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O17:K52:H18 (strain UMN026 / E... gi\|24053661, gi\|... - gi\|24114478\|ref\|NP_708988.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Shigella flexneri 2a... MURA_ECOL6 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 70... gi\|30042786, gi\|... - gi\|30064527\|ref\|NP_838698.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Shigella flexneri 2a... EG11358 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase / UDP-N-acetylglucosamine enoylpyruvyl transferase... gi\|194429095, gi... - gi\|75209632\|ref\|ZP_00709844.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... MURA_ECOHS - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=murA PE=3... MURA_ECO24 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase OS=Escherichia coli O139:H28 (strain E24377A / ETE... gi\|83585433, gi\|... - gi\|83585433\|ref\|ZP_00924079.1\| COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase [Escherichia... gi\|227835306, gi... - gi\|227887910\|ref\|ZP_04005715.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli ... gi\|251786459, gi... - gi\|251786459\|ref\|YP_003000763.1\| hypothetical protein B21_03005 [Escherichia coli BL21], gi\|24237873... gi\|253771977, gi... - gi\|254289881\|ref\|YP_003055629.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli... gi\|226839978, gi... - gi\|254038354\|ref\|ZP_04872412.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia sp. 1... gi\|253975032, gi... - gi\|254163131\|ref\|YP_003046239.1\| UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Escherichia coli...	0.0	[1..420]	[1..419]

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Predicted Domain #1

Region A:
Residues: [1-420]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKFRVQGRT RLSGEVTISG AKNAALPILF AALLAEEPVE LQNVPKLKDI DTTIKLLSQL  60
   61 GTKIERNNGS VFVDASAVNE FCAPYDLVKT MRASIWALGP LVARFGQGQV SLPGGCAIGA 120
  121 RPVDLHITGL EQLGAEIKLE EGYVKASVNG RLKGAHIVMD KVSVGATVTI MSAATLAEGT 180
  181 TVIENAAREP EIVDTANFLN TLGAKISGAG TDRITIEGVT RLGGGVYRVL PDRIETGTFL 240
  241 VAAAISGGKV VCRQTRPDTL DAVLAKLREA GADIEVGDDW ISLDMQGKRP KAITFRTAPH 300
  301 PGFPTDMQAQ FSLLNLVAEG TGVITETIFE NRFMHVPELI RMGAHAEIES NTVICYGVEQ 360
  361 LSGAQVMATD LRASASLVLA GCIAEGVTIV DRIYHIDRGY ERIEDKLRAL GAKIERVKGE 420
  421

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	147.0
Match:	1ejcA
Description:	UDP-N-acetylglucosamine enolpyruvyl transferase (EPT, MurA, MurZ)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	3.87711259634234	bayes_pls_golite062009
catalytic activity	2.91733519293428	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	2.15049036934665	bayes_pls_golite062009
transferase activity	1.9014276549152	bayes_pls_golite062009
3-phosphoshikimate 1-carboxyvinyltransferase activity	0.126471552426721	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: