YRC Public Data Repository - Protein Structure Prediction

Protein:	MUG_ECOLI
Organism:	Escherichia coli
Length:	168 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|85859396, gi\|... - gi\|85859396\|ref\|YP_461598.1\| uracil DNA glycosylase superfamily protein [Syntrophus aciditrophicus S...	179.0	[0..1]	[164..104]
gi\|221565894, gi... - gi\|222056605\|ref\|YP_002538967.1\| phage SPO1 DNA polymerase-related protein [Geobacter sp. FRC-32], g...	174.0	[0..1]	[164..96]
gi\|95134559, gi\|... - gi\|95929443\|ref\|ZP_01312186.1\| phage SPO1 DNA polymerase-related protein [Desulfuromonas acetoxidans...	174.0	[0..1]	[161..83]
gi\|148264964, gi... - gi\|88937846\|ref\|ZP_01143384.1\| Phage SPO1 DNA polymerase-related protein [Geobacter uraniumreducens ...	172.0	[0..1]	[161..98]
gi\|77919605, gi\|... - gi\|77919605\|ref\|YP_357420.1\| phage SpO1 DNA polymerase-related protein [Pelobacter carbinolicus DSM ...	172.0	[0..1]	[168..65]
gi\|67860259, gi\|... - gi\|67932514\|ref\|ZP_00525656.1\| Phage SPO1 DNA polymerase-related protein [Solibacter usitatus Ellin6...	172.0	[0..1]	[163..80]
gi\|68552582, gi\|... - gi\|68552582\|ref\|ZP_00591970.1\| Phage SPO1 DNA polymerase-related protein [Prosthecochloris aestuarii...	171.0	[0..1]	[166..46]
gi\|115364411, gi... - gi\|115378583\|ref\|ZP_01465737.1\| phage SPO1 DNA polymerase domain protein [Stigmatella aurantiaca DW4...	169.0	[0..1]	[164..161]
gi\|85775303, gi\|... - gi\|86158792\|ref\|YP_465577.1\| phage SPO1 DNA polymerase-related protein [Anaeromyxobacter dehalogenan...	169.0	[0..1]	[168..84]
gi\|78044945, gi\|... - gi\|78044945\|ref\|YP_359051.1\| uracil-DNA glycosylase [Carboxydothermus hydrogenoformans Z-2901], gi\|7...	168.0	[0..1]	[161..26]

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Predicted Domain #1

Region A:
Residues: [1-168]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEDILAPGL RVVFCGINPG LSSAGTGFPF AHPANRFWKV IYQAGFTDRQ LKPQEAQHLL  60
   61 DYRCGVTKLV DRPTVQANEV SKQELHAGGR KLIEKIEDYQ PQALAILGKQ AYEQGFSQRG 120
  121 AQWGKQTLTI GSTQIWVLPN PSGLSRVSLE KLVEAYRELD QALVVRGR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.221849
Match:	1mtlA
Description:	G:T/U mismatch-specific DNA glycosylase, Mug
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.06105429247323	bayes_pls_golite062009
hydrolase activity	0.68125450217484	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	0.52171393538922	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	0.513922158039369	bayes_pls_golite062009
DNA N-glycosylase activity	0.51291740673128	bayes_pls_golite062009
uracil DNA N-glycosylase activity	0.19043017897437	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: