YRC Public Data Repository - Protein Structure Prediction

Protein:	MTNN_ECOLI
Organism:	Escherichia coli
Length:	232 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTNN_ECOLI.

Description	E-value	Query Range	Subject Range
MTNN_HAES1 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Haemophilus somnus (strain 129Pt) GN=m...	193.0	[0..1]	[229..1]
gi\|46128809 - gi\|46128809\|ref\|ZP_00201937.1\| COG0775: Nucleoside phosphorylase [Haemophilus influenzae R2846]	192.0	[0..1]	[230..1]
MTNN_HISS2 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Histophilus somni (strain 2336) GN=mtn...	192.0	[0..1]	[229..1]
MTNN_PHOLL - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Photorhabdus luminescens subsp. laumon... MTNN_PHOLL - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Photorhabdus luminescens subsp. laumon...	191.0	[0..1]	[231..1]
gi\|89084479, gi\|... - gi\|89100833\|ref\|ZP_01173685.1\| 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [Bacillus ...	190.0	[0..1]	[231..1]
gi\|42631518 - gi\|42631518\|ref\|ZP_00157056.1\| COG0775: Nucleoside phosphorylase [Haemophilus influenzae R2866]	190.0	[0..1]	[229..1]
gi\|89095310, gi\|... - gi\|89095310\|ref\|ZP_01168229.1\| 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [Oceanospi...	190.0	[0..1]	[230..18]
MTNN_BACHD - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Bacillus halodurans (strain ATCC BAA-1... MTNN_BACHD - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Bacillus halodurans GN=mtnN PE=3 SV=1	190.0	[0..2]	[230..3]
gi\|46395046 - gi\|46395046\|gb\|AAS91661.1\| MTA/SAH nucleosidase; 5'-methylthioadenosine nucleosidase; S-adenosylhomo...	190.0	[0..1]	[229..1]
MTNN_HAEIN - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Haemophilus influenzae (strain ATCC 51... MTNN_HAEIN - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase OS=Haemophilus influenzae GN=mtnN PE=3 SV...	189.0	[0..1]	[229..1]

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Predicted Domain #1

Region A:
Residues: [1-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIGIIGAME EEVTLLRDKI ENRQTISLGG CEIYTGQLNG TEVALLKSGI GKVAAALGAT  60
   61 LLLEHCKPDV IINTGSAGGL APTLKVGDIV VSDEARYHDA DVTAFGYEYG QLPGCPAGFK 120
  121 ADDKLIAAAE ACIAELNLNA VRGLIVSGDA FINGSVGLAK IRHNFPQAIA VEMEATAIAH 180
  181 VCHNFNVPFV VVRAISDVAD QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	1jysA
Description:	5'-Methylthioadenosine/S-Adenosylhomocysteine nucleosidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-methyl-5-thioadenosine phosphorylase activity	3.89303327575747	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.66765825367784	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	3.65908655017573	bayes_pls_golite062009
catalytic activity	2.18268586151113	bayes_pls_golite062009
purine-nucleoside phosphorylase activity	1.46980781918487	bayes_pls_golite062009
binding	0.716947367672324	bayes_pls_golite062009
transferase activity	0.716715652241981	bayes_pls_golite062009
protein binding	0.294648445670962	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: