YRC Public Data Repository - Protein Structure Prediction

Protein:	MOEB_ECOLI
Organism:	Escherichia coli
Length:	249 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MOEB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|83756702, gi\|... - gi\|83815308\|ref\|YP_446148.1\| MoeZ/MoeB domain-contain protein [Salinibacter ruber DSM 13855], gi\|837...	303.0	[0..2]	[248..13]
gi\|114777472, gi... - gi\|114777472\|ref\|ZP_01452469.1\| molybdopterin biosynthesis protein MoeB [Mariprofundus ferrooxydans ...	303.0	[0..1]	[249..1]
gi\|117928984, gi... - gi\|88931318\|ref\|ZP_01137012.1\| Rhodanese-like [Acidothermus cellulolyticus 11B], gi\|88912597\|gb\|EAR3...	300.0	[0..4]	[249..13]
gi\|91203467 - gi\|91203467\|emb\|CAJ71120.1\| strongly similar to molybdopterin synthesis protein MoeB and thiamin bio...	296.0	[0..4]	[247..5]
gi\|83837900, gi\|... - gi\|83950001\|ref\|ZP_00958734.1\| Probable molybdopterin biosynthesis protein [Roseovarius nubinhibens ...	295.0	[0..4]	[248..102]
gi\|76800681, gi\|... - gi\|76800681\|ref\|YP_325689.1\| molybdenum cofactor biosynthesis protein MoeB [Natronomonas pharaonis D...	295.0	[0..1]	[248..1]
gi\|106891733, gi... - gi\|148654884\|ref\|YP_001275089.1\| UBA/THIF-type NAD/FAD binding protein [Roseiflexus sp. RS-1], gi\|14...	294.0	[0..1]	[248..3]
gi\|45545541, gi\|... - gi\|68563155\|ref\|ZP_00602357.1\| UBA/THIF-type NAD/FAD binding fold:Rhodanese-like:MoeZ/MoeB [Rubrobac...	292.0	[0..3]	[249..14]
gi\|7448808 - pir\|\|A70415 molybdopterin biosynthesis protein MoeB - Aquifex aeolicus gi\|2983752, gi\|1... - gi\|2983752\|gb\|AAC07312.1\| molybdopterin biosynthesis protein MoeB [Aquifex aeolicus VF5], gi\|1560653...	292.0	[0..1]	[249..1]
gi\|222526984, gi... - gi\|222526984\|ref\|YP_002571455.1\| UBA/THIF-type NAD/FAD binding protein [Chloroflexus sp. Y-400-fl], ... gi\|53796678 - ref\|ZP_00020762.2\| COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine bi... gi\|163849021, gi... - gi\|76258733\|ref\|ZP_00766387.1\| UBA/THIF-type NAD/FAD binding fold:Rhodanese-like:MoeZ/MoeB [Chlorofl...	292.0	[0..1]	[248..1]

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Predicted Domain #1

Region A:
Residues: [1-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELSDQEML RYNRQIILRG FDFDGQEALK DSRVLIVGLG GLGCAASQYL ASAGVGNLTL  60
   61 LDFDTVSLSN LQRQTLHSDA TVGQPKVESA RDALTRINPH IAITPVNALL DDAELAALIA 120
  121 EHDLVLDCTD NVAVRNQLNA GCFAAKVPLV SGAAIRMEGQ ITVFTYQDGE PCYRCLSRLF 180
  181 GENALTCVEA GVMAPLIGVI GSLQAMEAIK MLAGYGKPAS GKIVMYDAMT CQFREMKLMR 240
  241 NPGCEVCGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.39794
Match:	1jw9B
Description:	Molybdenum cofactor biosynthesis protein MoeB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
small protein activating enzyme activity	1.61603220653307	bayes_pls_golite062009
catalytic activity	1.59245438598251	bayes_pls_golite062009
URM1 activating enzyme activity	0.936791644743361	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: