YRC Public Data Repository - Protein Structure Prediction

Protein:	MOEA_ECOLI
Organism:	Escherichia coli
Length:	411 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MOEA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110804826, gi... - gi\|110804826\|ref\|YP_688346.1\| molybdopterin biosynthesis protein MoeA [Shigella flexneri 5 str. 8401...	461.0	[0..1]	[411..1]
gi\|75178381, gi\|... - gi\|75178381\|ref\|ZP_00698435.1\| COG0303: Molybdopterin biosynthesis enzyme [Shigella boydii BS512], g... gi\|73854849, gi\|... - gi\|74311372\|ref\|YP_309791.1\| molybdopterin biosynthesis protein MoeA [Shigella sonnei Ss046], gi\|738... gi\|81244683, gi\|... - gi\|82543272\|ref\|YP_407219.1\| molybdopterin biosynthesis protein MoeA [Shigella boydii Sb227], gi\|812...	461.0	[0..1]	[411..1]
gi\|75512832, gi\|... - gi\|75512832\|ref\|ZP_00735324.1\| COG0303: Molybdopterin biosynthesis enzyme [Escherichia coli 53638], ...	461.0	[0..1]	[411..1]
gi\|191166190, gi... - gi\|75230675\|ref\|ZP_00717146.1\| COG0303: Molybdopterin biosynthesis enzyme [Escherichia coli B7A], gi...	460.0	[0..1]	[411..1]
gi\|218364500, gi... - gi\|218557731\|ref\|YP_002390644.1\| molybdopterin biosynthesis protein MoeA [Escherichia coli S88], gi\|... gi\|226898420, gi... - gi\|237707210\|ref\|ZP_04537691.1\| molybdopterin biosynthesis protein MoeA [Escherichia sp. 3_2_53FAA],... gi\|91209861, gi\|... - gi\|91209861\|ref\|YP_539847.1\| molybdopterin biosynthesis protein MoeA [Escherichia coli UTI89], gi\|91... gi\|115512130, gi... - gi\|117623006\|ref\|YP_851919.1\| molybdopterin biosynthesis protein MoeA [Escherichia coli APEC O1], gi...	460.0	[0..1]	[411..1]
gi\|68058219, gi\|... - gi\|68250020\|ref\|YP_249132.1\| molybdopterin biosynthesis protein MoeA [Haemophilus influenzae 86-028N... gi\|148825991, gi... - gi\|148825991\|ref\|YP_001290744.1\| GTP cyclohydrolase I [Haemophilus influenzae PittEE], gi\|148716151\|... gi\|229810183, gi... - gi\|229846694\|ref\|ZP_04466801.1\| GTP cyclohydrolase I [Haemophilus influenzae 7P49H1], gi\|229810183\|g...	459.0	[0..7]	[409..1]
MOEA_HAEIN - Molybdopterin molybdenumtransferase OS=Haemophilus influenzae GN=moeA PE=3 SV=1 MOEA_HAEIN - Molybdopterin molybdenumtransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 ...	459.0	[0..7]	[409..1]
gi\|42629477 - gi\|42629477\|ref\|ZP_00155023.1\| COG0303: Molybdopterin biosynthesis enzyme [Haemophilus influenzae R2...	459.0	[0..7]	[409..1]
gi\|192957308, gi... - gi\|75236116\|ref\|ZP_00720240.1\| COG0303: Molybdopterin biosynthesis enzyme [Escherichia coli E110019]... gi\|75189868, gi\|... - gi\|75189868\|ref\|ZP_00703135.1\| COG0303: Molybdopterin biosynthesis enzyme [Escherichia coli E24377A]... gi\|218351033, gi... - gi\|218694301\|ref\|YP_002401968.1\| molybdopterin biosynthesis protein MoeA [Escherichia coli 55989], g...	459.0	[0..1]	[411..1]
gi\|110641030, gi... - gi\|110641030\|ref\|YP_668758.1\| molybdopterin biosynthesis protein MoeA [Escherichia coli 536], gi\|110... gi\|75238160, gi\|... - gi\|75238160\|ref\|ZP_00722164.1\| COG0303: Molybdopterin biosynthesis enzyme [Escherichia coli F11], gi...	459.0	[0..1]	[411..1]

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Predicted Domain #1

Region A:
Residues: [1-411]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFTTGLMSL DTALNEMLSR VTPLTAQETL PLVQCFGRIL ASDVVSPLDV PGFDNSAMDG  60
   61 YAVRLADIAS GQPLPVAGKS FAGQPYHGEW PAGTCIRIMT GAPVPEGCEA VVMQEQTEQM 120
  121 DNGVRFTAEV RSGQNIRRRG EDISAGAVVF PAGTRLTTAE LPVIASLGIA EVPVIRKVRV 180
  181 ALFSTGDELQ LPGQPLGDGQ IYDTNRLAVH LMLEQLGCEV INLGIIRDDP HALRAAFIEA 240
  241 DSQADVVISS GGVSVGEADY TKTILEELGE IAFWKLAIKP GKPFAFGKLS NSWFCGLPGN 300
  301 PVSATLTFYQ LVQPLLAKLS GNTASGLPAR QRVRTASRLK KTPGRLDFQR GVLQRNADGE 360
  361 LEVTTTGHQG SHIFSSFSLG NCFIVLERDR GNVEVGEWVE VEPFNALFGG L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	125.0
Match:	1fc5A
Description:	Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain; Molybdenum cofactor biosynthesis protein MoeA, N-terminal and linker domains; MoeA, central domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.15974340242656	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: