YRC Public Data Repository - Protein Structure Prediction

Protein:	MOAA_ECOLI
Organism:	Escherichia coli
Length:	329 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MOAA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|68545079, gi\|... - gi\|68545079\|ref\|ZP_00584630.1\| Radical SAM:Molybdenum cofactor synthesis C [Shewanella amazonensis S...	275.0	[0..1]	[329..14]
gi\|69951946, gi\|... - gi\|69951946\|ref\|ZP_00639558.1\| Radical SAM:Molybdenum cofactor synthesis C [Shewanella frigidimarina...	274.0	[0..2]	[329..12]
gi\|113890677, gi... - gi\|78691074\|ref\|ZP_00855705.1\| Elongator protein 3/MiaB/NifB [Shewanella sp. MR-7], gi\|78509528\|gb\|E...	273.0	[0..1]	[329..11]
gi\|188494750, gi... - gi\|188494750\|ref\|ZP_03002020.1\| molybdenum cofactor biosynthesis protein A [Escherichia coli 53638],... gi\|26246752, gi\|... - gi\|26246752\|ref\|NP_752792.1\| molybdenum cofactor biosynthesis protein A [Escherichia coli CFT073], g...	273.0	[0..1]	[329..28]
gi\|126172537, gi... - gi\|68541241\|ref\|ZP_00580987.1\| Radical SAM:Molybdenum cofactor synthesis C [Shewanella baltica OS155... gi\|151363448, gi... - gi\|152998830\|ref\|YP_001364511.1\| molybdenum cofactor biosynthesis protein A [Shewanella baltica OS18... gi\|217496625, gi... - gi\|217971490\|ref\|YP_002356241.1\| molybdenum cofactor biosynthesis protein A [Shewanella baltica OS22...	273.0	[0..1]	[329..11]
gi\|89203336, gi\|... - gi\|89203336\|ref\|ZP_01182016.1\| Radical SAM:Molybdenum cofactor synthesis C-terminal [Bacillus cereus... gi\|71668643, gi\|... - gi\|71678200\|ref\|ZP_00675922.1\| Radical SAM:Molybdenum cofactor synthesis C [Trichodesmium erythraeum... gi\|68006966, gi\|... - gi\|68056442\|ref\|ZP_00540562.1\| Radical SAM:Molybdenum cofactor synthesis C-terminal [Exiguobacterium...	273.0	[0..1]	[329..12]
gi\|113908451, gi... - gi\|160873411\|ref\|YP_001552727.1\| molybdenum cofactor biosynthesis protein A [Shewanella baltica OS19...	273.0	[0..1]	[329..11]
MOAA_HAEIN - Molybdenum cofactor biosynthesis protein A OS=Haemophilus influenzae GN=moaA PE=3 SV=1 MOAA_HAEIN - Cyclic pyranopterin monophosphate synthase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 ...	273.0	[0..3]	[329..12]
MOAA_HAEI8 - Cyclic pyranopterin monophosphate synthase OS=Haemophilus influenzae (strain 86-028NP) GN=moaA PE=3 ...	273.0	[0..3]	[329..12]
gi\|110614330, gi... - gi\|110804782\|ref\|YP_688302.1\| molybdenum cofactor biosynthesis protein A [Shigella flexneri 5 str. 8...	273.0	[0..1]	[329..12]

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Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASQLTDAFA RKFYYLRLSI TDVCNFRCTY CLPDGYKPSG VTNKGFLTVD EIRRVTRAFA  60
   61 RLGTEKVRLT GGEPSLRRDF TDIIAAVREN DAIRQIAVTT NGYRLERDVA SWRDAGLTGI 120
  121 NVSVDSLDAR QFHAITGQDK FNQVMAGIDA AFEAGFEKVK VNTVLMRDVN HHQLDTFLNW 180
  181 IQHRPIQLRF IELMETGEGS ELFRKHHISG QVLRDELLRR GWIHQLRQRS DGPAQVFCHP 240
  241 DYAGEIGLIM PYEKDFCATC NRLRVSSIGK LHLCLFGEGG VNLRDLLEDD TQQQALEARI 300
  301 SAALREKKQT HFLHQNNTGI TQNLSYIGG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.39794
Match:	1tv7A
Description:	Structure of the S-adenosylmethionine dependent Enzyme MoaA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.85375915825216	bayes_pls_golite062009
biotin synthase activity	1.62334351678868	bayes_pls_golite062009
radical SAM enzyme activity	1.4803934989213	bayes_pls_golite062009
sulfurtransferase activity	1.26112752511053	bayes_pls_golite062009
coproporphyrinogen oxidase activity	1.25473129160872	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	0.548175475004449	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	0.35292941647096	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: