YRC Public Data Repository - Protein Structure Prediction

Protein:	MIA_BOVIN
Organism:	Bos taurus
Length:	130 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIA_BOVIN.

Description	E-value	Query Range	Subject Range
MIA_MOUSE - Melanoma-derived growth regulatory protein OS=Mus musculus GN=Mia PE=2 SV=2	134.0	[0..1]	[130..1]
MIA_RAT - Melanoma-derived growth regulatory protein OS=Rattus norvegicus GN=Mia PE=2 SV=2	132.0	[0..1]	[130..1]
gi\|60832750 - gi\|60832750\|gb\|AAX37023.1\| melanoma inhibitory activity [synthetic construct]	130.0	[0..1]	[130..1]
MIA - melanoma inhibitory activity gi\|55649185, gi\|... - gi\|55649185\|ref\|XP_512675.1\| PREDICTED: melanoma inhibitory activity isoform 3 [Pan troglodytes], gi... gi\|61361652 - gi\|61361652\|gb\|AAX42081.1\| melanoma inhibitory activity [synthetic construct]	130.0	[0..1]	[130..1]
gi\|73948308 - gi\|73948308\|ref\|XP_541610.2\| PREDICTED: similar to Melanoma derived growth regulatory protein precur...	128.0	[0..1]	[130..1]
gi\|109124844, gi... - gi\|109124844\|ref\|XP_001098701.1\| PREDICTED: melanoma inhibitory activity isoform 2 [Macaca mulatta],...	122.0	[0..1]	[130..1]
gi\|190337030, gi... - gi\|68397265\|ref\|XP_698306.1\| PREDICTED: similar to cartilage-derived retinoic acid-sensitive protein...	112.0	[0..3]	[129..8]

Back

Predicted Domain #1

Region A:
Residues: [1-130]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWSLVFLGV VLLSAFPGPS AGGRPMPKLA DRKMCADEEC SHPISVAVAL QDYVAPDCRF  60
   61 LTIHQGQVVY IFSKLKGRGR LFWGGSVQGD YYGDGAARLG YFPSSIVRED QTLKPAKTDV 120
  121 KTDIWDFYCQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	1i1jA
Description:	Melanoma inhibitory activity protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.0198140785578	bayes_pls_golite062009
protein binding	1.85368024495439	bayes_pls_golite062009
receptor binding	1.46964167495514	bayes_pls_golite062009
cytoskeletal protein binding	0.313587086905048	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: