YRC Public Data Repository - Protein Structure Prediction

Protein:	MHPB_ECOLI
Organism:	Escherichia coli
Length:	314 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MHPB_ECOLI.

Description	E-value	Query Range	Subject Range
MHPB_PHOLL - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Photorhabdus luminescens... MHPB_PHOLL - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Photorhabdus luminescens...	269.0	[0..1]	[312..1]
MHPB_ECOHS - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Escherichia coli O9:H4 (... MHPB_ECO24 - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Escherichia coli O139:H2... MHPB_ECOSE - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Escherichia coli (strain... MHPB_ECO8A - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Escherichia coli O8 (str... gi\|191169384, gi... - gi\|75227294\|ref\|ZP_00714083.1\| hypothetical protein EcolB7_01004263 [Escherichia coli B7A], gi\|19116...	266.0	[0..1]	[314..1]
gi\|75512412, gi\|... - gi\|75512412\|ref\|ZP_00734951.1\| hypothetical protein Ecol5_01003327 [Escherichia coli 53638], gi\|1884...	264.0	[0..1]	[314..1]
gi\|1665747 - gi\|1665747\|dbj\|BAA13053.1\| MhpB [Escherichia coli] gi\|1665747 - gi\|1665747\|dbj\|BAA13053.1\| MhpB [Escherichia coli W3110]	259.0	[0..1]	[314..1]
gi\|61660057 - gi\|61660057\|gb\|AAX50134.1\| CbzE2 [Pseudomonas putida]	255.0	[0..1]	[313..35]
MHPB_CUPPJ - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Cupriavidus pinatubonens...	247.0	[0..1]	[312..1]
MHPB_RHOGO - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Rhodococcus globerulus G...	246.0	[0..1]	[310..1]
MHPB1_DECAR - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase 1 OS=Dechloromonas aromatic...	245.0	[0..1]	[313..1]
MHPB_BURXL - 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase OS=Burkholderia xenovorans ...	245.0	[0..1]	[312..1]

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Predicted Domain #1

Region A:
Residues: [1-314]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHAYLHCLSH SPLVGYVDPA QEVLDEVNGV IASARERIAA FSPELVVLFA PDHYNGFFYD  60
   61 VMPPFCLGVG ATAIGDFGSA AGELPVPVEL AEACAHAVMK SGIDLAVSYC MQVDHGFAQP 120
  121 LEFLLGGLDK VPVLPVFING VATPLPGFQR TRMLGEAIGR FTSTLNKRVL FLGSGGLSHQ 180
  181 PPVPELAKAD AHMRDRLLGS GKDLPASERE LRQQRVISAA EKFVEDQRTL HPLNPIWDNQ 240
  241 FMTLLEQGRI QELDAVSNEE LSAIAGKSTH EIKTWVAAFA AISAFGNWRS EGRYYRPIPE 300
  301 WIAGFGSLSA RTEN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.30103
Match:	1b4uB
Description:	LigB subunit of an aromatic-ring-opening dioxygenase LigAB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.109061360360795	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: