YRC Public Data Repository - Protein Structure Prediction

Protein:	MCP2_ECOLI
Organism:	Escherichia coli
Length:	553 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCP2_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|67153635 - gi\|67153635\|ref\|ZP_00415380.1\| Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer... gi\|67087768, gi\|... - gi\|67153635\|ref\|ZP_00415380.1\| Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer...	307.0	[0..2]	[553..662]
gi\|62180496, gi\|... - gi\|62180496\|ref\|YP_216913.1\| methyl accepting chemotaxis protein II, aspartate sensor-receptor [Salm...	282.0	[0..1]	[553..78]
gi\|91211110, gi\|... - gi\|91211110\|ref\|YP_541096.1\| methyl-accepting chemotaxis protein II [Escherichia coli UTI89], gi\|910...	280.0	[0..1]	[553..8]
gi\|26248153, gi\|... - gi\|26248153\|ref\|NP_754193.1\| methyl-accepting chemotaxis protein II [Escherichia coli CFT073], gi\|26...	280.0	[0..1]	[553..8]
gi\|89901008, gi\|... - gi\|89901008\|ref\|YP_523479.1\| methyl-accepting chemotaxis sensory transducer [Rhodoferax ferrireducen...	279.0	[0..2]	[533..4]
gi\|75190914, gi\|... - gi\|75190914\|ref\|ZP_00704181.1\| COG0840: Methyl-accepting chemotaxis protein [Escherichia coli E24377...	279.0	[0..1]	[553..1]
gi\|168770873, gi... - gi\|189360314\|gb\|EDU78733.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|187768041, gi... - gi\|187768041\|gb\|EDU31885.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|188999453, gi... - gi\|188999453\|gb\|EDU68439.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|168789755, gi... - gi\|189370680\|gb\|EDU89096.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|188017376, gi... - gi\|188017376\|gb\|EDU55498.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|168757925, gi... - gi\|189355188\|gb\|EDU73607.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|189367395, gi... - gi\|189367395\|gb\|EDU85811.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|13362064, gi\|... - gi\|15831850\|ref\|NP_310623.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. S... gi\|254592910, gi... - gi\|254793510\|ref\|YP_003078347.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 st... gi\|209767250, gi... - pir\|\|D90953 methyl-accepting chemotaxis protein II [imported] - Escherichia coli (strain O157:H7, su... gi\|13362064, gi\|... - gi\|15831850\|ref\|NP_310623.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7], gi\|1... gi\|208821820, gi... - gi\|208821820\|ref\|ZP_03262140.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str... gi\|217318336, gi... - gi\|217328989\|ref\|ZP_03445070.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str... gi\|189376035, gi... - gi\|189376035\|gb\|EDU94451.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC... gi\|195939590 - gi\|195939590\|ref\|ZP_03084972.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str... gi\|208725087, gi... - gi\|208810571\|ref\|ZP_03252447.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str... gi\|208731234, gi... - gi\|208816891\|ref\|ZP_03258011.1\| methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str...	279.0	[0..1]	[553..1]
gi\|56383546, gi\|... - gi\|56479995\|ref\|NP_707781.2\| methyl-accepting chemotaxis protein II, aspartate sensor receptor [Shig... gi\|30041590, gi\|... - gi\|30063338\|ref\|NP_837509.1\| methyl-accepting chemotaxis protein II, aspartate sensor receptor [Shig...	278.0	[0..1]	[553..1]
gi\|145521 - gi\|145521\|gb\|AAA23566.1\| methyl-accepting chemotaxis protein II [Escherichia coli]	278.0	[0..1]	[553..1]
gi\|193065446, gi... - gi\|75256494\|ref\|ZP_00728140.1\| COG0840: Methyl-accepting chemotaxis protein [Escherichia coli E22], ... gi\|75209437, gi\|... - gi\|75209437\|ref\|ZP_00709665.1\| COG0840: Methyl-accepting chemotaxis protein [Escherichia coli B171],...	278.0	[0..1]	[553..1]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINRIRVVTL LVMVLGVFAL LQLISGSLFF SSLHHSQKSF VVSNQLREQQ GELTSTWDLM  60
   61 LQTRINLSRS AVRMMMDSSN QQSNAKVELL DSARKTLAQA ATHYKKFKSM APLPEMVATS 120
  121 RNIDEKYKNY YTALTELIDY LDYGNTGAYF AQPTQGMQNA MGEAFAQYAL SSEK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	37.853872
Match:	PF02203.6
Description:	No description for PF02203.6 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.904	N/A	N/A	a.24.3	Cytochromes
View	Download	0.878	N/A	N/A	a.24.9	alpha-catenin/vinculin
View	Download	0.874	N/A	N/A	a.24.2	Aspartate receptor, ligand-binding domain
View	Download	0.797	N/A	N/A	a.24.16	Nucleotidyltransferase substrate binding subunit/domain
View	Download	0.790	N/A	N/A	a.24.9	alpha-catenin/vinculin

Predicted Domain #2

Region A:
Residues: [175-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYRDIVTDNA DDYRFAQWQL AVIALVVVLI LLVAWYGIRR MLLTPLAKII AHIREIAGGN  60
   61 LANTLTIDGR SEMGDLAQSV SHMQRSLTDT VTHVREGSDA IYAGTREIAA GNTDL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.94
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [290-553]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSRTEQQASA LEETAASMEQ LTATVKQNAD NARQASQLAQ SASDTAQHGG KVVDGVVKTM  60
   61 HEIADSSKKI ADIISVIDGI AFQTNILALN AAVEAARAGE QGRGFAVVAG EVRNLASRSA 120
  121 QAAKEIKALI EDSVSRVDTG SVLVESAGET MNNIVNAVTR VTDIMGEIAS ASDEQSRGID 180
  181 QVALAVSEMD RVTQQNASLV QESAAAAAAL EEQASRLTQA VSAFRLAASP LTNKPQTPSR 240
  241 PASEQPPAQP RLRIAEQDPN WETF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.045757
Match:	1qu7A
Description:	Cytoplasmic domain of a serine chemotaxis receptor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits