YRC Public Data Repository - Protein Structure Prediction

Protein:	MALZ_ECOLI
Organism:	Escherichia coli
Length:	605 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MALZ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194419089, gi... - gi\|83570329\|ref\|ZP_00921774.1\| COG0366: Glycosidases [Shigella dysenteriae 1012], gi\|194432528\|ref\|Z...	439.0	[0..1]	[605..1]
gi\|218364081, gi... - gi\|218557312\|ref\|YP_002390225.1\| maltodextrin glucosidase [Escherichia coli S88], gi\|218364081\|emb\|C... gi\|117622664, gi... - gi\|117622664\|ref\|YP_851577.1\| maltodextrin glucosidase [Escherichia coli APEC O1], gi\|115511788\|gb\|A... gi\|91209471, gi\|... - gi\|91209471\|ref\|YP_539457.1\| maltodextrin glucosidase [Escherichia coli UTI89], gi\|91071045\|gb\|ABE05...	438.0	[0..1]	[605..1]
gi\|253972371, gi... - gi\|254160470\|ref\|YP_003043578.1\| maltodextrin glucosidase [Escherichia coli B str. REL606], gi\|25397... gi\|169756153, gi... - gi\|170021225\|ref\|YP_001726179.1\| maltodextrin glucosidase [Escherichia coli ATCC 8739], gi\|169756153... gi\|188493047, gi... - gi\|75512464\|ref\|ZP_00735003.1\| COG0366: Glycosidases [Escherichia coli 53638], gi\|188493047\|ref\|ZP_0... gi\|253976580, gi... - gi\|254287273\|ref\|YP_003053021.1\| maltodextrin glucosidase [Escherichia coli BL21(DE3)], gi\|253976580... gi\|194422204, gi... - gi\|83585678\|ref\|ZP_00924320.1\| COG0366: Glycosidases [Escherichia coli 101-1], gi\|194438910\|ref\|ZP_0... gi\|124528886, gi... - gi\|124528886\|ref\|ZP_01700071.1\| alpha amylase, catalytic region [Escherichia coli B], gi\|124500223\|g... gi\|251783908, gi... - gi\|251783908\|ref\|YP_002998212.1\| hypothetical protein B21_00355 [Escherichia coli BL21], gi\|24237618...	438.0	[0..1]	[605..1]
gi\|188999412, gi... - gi\|189010636\|ref\|ZP_02808269.2\| maltodextrin glucosidase [Escherichia coli O157:H7 str. EC4076], gi\|... gi\|13359910, gi\|... - gi\|15829707\|ref\|NP_308480.1\| maltodextrin glucosidase [Escherichia coli O157:H7 str. Sakai], gi\|1335... gi\|189373544, gi... - gi\|189404816\|ref\|ZP_02811250.2\| maltodextrin glucosidase [Escherichia coli O157:H7 str. EC869], gi\|1... gi\|189404000, gi... - gi\|189404000\|ref\|ZP_02786609.2\| maltodextrin glucosidase [Escherichia coli O157:H7 str. EC4501], gi\|... gi\|189362474, gi... - gi\|189403119\|ref\|ZP_02793354.2\| maltodextrin glucosidase [Escherichia coli O157:H7 str. EC4486], gi\|... gi\|189355979, gi... - gi\|189402357\|ref\|ZP_02781945.2\| maltodextrin glucosidase [Escherichia coli O157:H7 str. EC4401], gi\|... gi\|25289314, gi\|... - pir\|\|E90685 maltodextrin glucosidase [imported] - Escherichia coli (strain O157:H7, substrain RIMD ... gi\|208822973, gi... - gi\|208822973\|ref\|ZP_03263291.1\| maltodextrin glucosidase [Escherichia coli O157:H7 str. EC4042], gi\|... gi\|254791583, gi... - gi\|254791583\|ref\|YP_003076420.1\| maltodextrin glucosidase [Escherichia coli O157:H7 str. TW14359], g... gi\|13359910, gi\|... - gi\|15829707\|ref\|NP_308480.1\| maltodextrin glucosidase [Escherichia coli O157:H7], gi\|13359910\|dbj\|BA...	437.0	[0..1]	[605..1]
gi\|110640664, gi... - gi\|110640664\|ref\|YP_668392.1\| maltodextrin glucosidase [Escherichia coli 536], gi\|110342256\|gb\|ABG68... gi\|191173498, gi... - gi\|75238730\|ref\|ZP_00722718.1\| COG0366: Glycosidases [Escherichia coli F11], gi\|191173498\|ref\|ZP_030...	437.0	[0..1]	[605..1]
gi\|15800129, gi\|... - gi\|15800129\|ref\|NP_286141.1\| maltodextrin glucosidase [Escherichia coli O157:H7 EDL933], gi\|12513249... gi\|25289317 - pir\|\|A85536 maltodextrin glucosidase [imported] - Escherichia coli (strain O157:H7, substrain EDL93...	436.0	[0..1]	[605..1]
gi\|75237216, gi\|... - gi\|75237216\|ref\|ZP_00721263.1\| COG0366: Glycosidases [Escherichia coli E110019], gi\|193068700\|ref\|ZP... gi\|194428844, gi... - gi\|75209959\|ref\|ZP_00710148.1\| COG0366: Glycosidases [Escherichia coli B171], gi\|194428844\|ref\|ZP_03... gi\|209910874, gi... - gi\|209917615\|ref\|YP_002291699.1\| maltodextrin glucosidase [Escherichia coli SE11], gi\|209910874\|dbj\|... gi\|75256775, gi\|... - gi\|75256775\|ref\|ZP_00728380.1\| COG0366: Glycosidases [Escherichia coli E22], gi\|193065169\|ref\|ZP_030...	435.0	[0..1]	[605..1]
gi\|24111781, gi\|... - gi\|24111781\|ref\|NP_706291.1\| maltodextrin glucosidase [Shigella flexneri 2a str. 301], gi\|24050568\|g... gi\|30040143, gi\|... - gi\|30061899\|ref\|NP_836070.1\| maltodextrin glucosidase [Shigella flexneri 2a str. 2457T], gi\|30040143...	435.0	[0..1]	[605..1]
gi\|218350596, gi... - gi\|218693864\|ref\|YP_002401531.1\| maltodextrin glucosidase [Escherichia coli 55989], gi\|218350596\|emb... gi\|191166722, gi... - gi\|75230128\|ref\|ZP_00716632.1\| COG0366: Glycosidases [Escherichia coli B7A], gi\|191166722\|ref\|ZP_030... gi\|75189470, gi\|... - gi\|75189470\|ref\|ZP_00702737.1\| COG0366: Glycosidases [Escherichia coli E24377A], gi\|157156114\|ref\|YP...	434.0	[0..1]	[605..1]
gi\|157065603, gi... - gi\|75194622\|ref\|ZP_00704692.1\| COG0366: Glycosidases [Escherichia coli HS], gi\|157159923\|ref\|YP_0014...	434.0	[0..1]	[605..1]

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Predicted Domain #1

Region A:
Residues: [1-605]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLNAWHLPV PPFVKQSKDQ LLITLWLTGE DPPQRIMLRT EHDNEEMSVP MHKQRSQPQP  60
   61 GVTAWRAAID LSSGQPRRRY SFKLLWHDRQ RWFTPQGFSR MPPARLEQFA VDVPDIGPQW 120
  121 AADQIFYQIF PDRFARSLPR EAEQDHVYYH HAAGQEIILR DWDEPVTAQA GGSTFYGGDL 180
  181 DGISEKLPYL KKLGVTALYL NPVFKAPSVH KYDTEDYRHV DPQFGGDGAL LRLRHNTQQL 240
  241 GMRLVLDGVF NHSGDSHAWF DRHNRGTGGA CHNPESPWRD WYSFSDDGTA LDWLGYASLP 300
  301 KLDYQSESLV NEIYRGEDSI VRHWLKAPWN MDGWRLDVVH MLGEAGGARN NMQHVAGITE 360
  361 AAKETQPEAY IVGEHFGDAR QWLQADVEDA AMNYRGFTFP LWGFLANTDI SYDPQQIDAQ 420
  421 TCMAWMDNYR AGLSHQQQLR MFNQLDSHDT ARFKTLLGRD IARLPLAVVW LFTWPGVPCI 480
  481 YYGDEVGLDG KNDPFCRKPF PWQVEKQDTA LFALYQRMIA LRKKSQALRH GGCQVLYAED 540
  541 NVVVFVRVLN QQRVLVAINR GEACEVVLPA SPFLNAVQWQ CKEGHGQLTD GILALPAISA 600
  601 TVWMN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1j0hA
Description:	Neopullulanase, central domain; Neopullulanase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, acting on glycosyl bonds	4.03630657705134	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	3.47174391073813	bayes_pls_golite062009
hydrolase activity	2.98140830993539	bayes_pls_golite062009
alpha-amylase activity	2.09193270404736	bayes_pls_golite062009
amylase activity	2.03484942782894	bayes_pls_golite062009
chitinase activity	1.947859226275	bayes_pls_golite062009
catalytic activity	1.85569074294201	bayes_pls_golite062009
glucosidase activity	0.766503513427695	bayes_pls_golite062009
hexosaminidase activity	0.763360027922833	bayes_pls_golite062009
binding	0.63693798355947	bayes_pls_golite062009
carbohydrate binding	0.28185708488534	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	0.266938437560648	bayes_pls_golite062009
beta-N-acetylhexosaminidase activity	0.263065978664289	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: