YRC Public Data Repository - Protein Structure Prediction

Protein:	CLC
Organism:	Homo sapiens
Length:	141 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLC.

Description	E-value	Query Range	Subject Range
LEG4_RAT - Galectin-4 OS=Rattus norvegicus GN=Lgals4 PE=1 SV=1	173.0	[0..2]	[140..16]
gi\|130502092, gi... - gi\|5882169\|gb\|AAD55242.1\|AF091738_1 galectin-4 [Oryctolagus cuniculus], gi\|130502092\|ref\|NP_00107618...	171.0	[0..2]	[140..16]
gi\|73948388 - gi\|73948388\|ref\|XP_855387.1\| PREDICTED: similar to Galectin-4 (Lactose-binding lectin 4) (L-36 lacto...	171.0	[0..2]	[139..63]
LEG4_MOUSE - Galectin-4 OS=Mus musculus GN=Lgals4 PE=1 SV=2 gi\|123253370, gi... - gi\|123253370\|gb\|ABM74073.1\| galectin-4 [Mus spretus], gi\|123253360\|gb\|ABM74072.1\| galectin-4 [Mus sp... gi\|123253350 - gi\|123253350\|gb\|ABM74071.1\| galectin-4 [Mus musculus domesticus] gi\|123253334 - gi\|123253334\|gb\|ABM74070.1\| galectin-4 [Mus musculus castaneus]	170.0	[0..2]	[140..16]
gi\|114668564, gi... - gi\|114668566\|ref\|XP_511349.2\| PREDICTED: galectin 9 isoform 4 [Pan troglodytes], gi\|114668564\|ref\|XP...	169.0	[0..2]	[140..14]
gi\|61371621, gi\|... - gi\|61371627\|gb\|AAX43702.1\| lectin galactoside-binding soluble 4 [synthetic construct], gi\|61371621\|g...	169.0	[0..2]	[140..16]
gi\|60655029, gi\|... - gi\|60655029\|gb\|AAX32078.1\| lectin galactoside-binding soluble 4 [synthetic construct], gi\|60655027\|g... LGALS4 - lectin, galactoside-binding, soluble, 4	168.0	[0..2]	[140..16]
LEG9_BOVIN - Galectin-9 OS=Bos taurus GN=LGALS9 PE=2 SV=1	168.0	[0..2]	[140..14]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLLPVPYTEA ASLSTGSTVT IKGRPLVCFL NEPYLQVDFH TEMKEESDIV FHFQVCFGRR  60
   61 VVMNSREYGA WKQQVESKNM PFQDGQEFEL SISVLPDKYQ VMVNGQSSYT FDHRIKPEAV 120
  121 KMVQVWRDIS LTKFNVSYLK R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.39794
Match:	1g86A
Description:	Charcot-Leyden crystal (CLC) protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.624576451755109	bayes_pls_golite062009
protein binding	0.0619452338835049	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: