YRC Public Data Repository - Protein Structure Prediction

Protein:	KCY_ECOLI
Organism:	Escherichia coli
Length:	227 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KCY_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|90581252, gi\|... - gi\|90581252\|ref\|ZP_01237050.1\| cytidylate kinase [Vibrio angustum S14], gi\|90437623\|gb\|EAS62816.1\| c... gi\|89050220, gi\|... - gi\|89074082\|ref\|ZP_01160583.1\| cytidylate kinase [Photobacterium sp. SKA34], gi\|89050220\|gb\|EAR55731...	202.0	[0..1]	[225..1]
gi\|90326951, gi\|... - gi\|90412227\|ref\|ZP_01220233.1\| cytidylate kinase [Photobacterium profundum 3TCK], gi\|90326951\|gb\|EAS...	201.0	[0..1]	[226..1]
gi\|86146933, gi\|... - gi\|86146933\|ref\|ZP_01065251.1\| cytidylate kinase [Vibrio sp. MED222], gi\|85835183\|gb\|EAQ53323.1\| cyt... KCY_VIBTL - Cytidylate kinase OS=Vibrio tasmaniensis (strain LGP32) GN=cmk PE=3 SV=1	201.0	[0..1]	[225..1]
KCY_PHOPR - Cytidylate kinase OS=Photobacterium profundum GN=cmk PE=3 SV=2 KCY_PHOPR - Cytidylate kinase OS=Photobacterium profundum (strain SS9) GN=cmk PE=3 SV=2	201.0	[0..1]	[226..1]
KCY_VIBPA - Cytidylate kinase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=cmk PE=3 SV=1 KCY_VIBPA - Cytidylate kinase OS=Vibrio parahaemolyticus GN=cmk PE=3 SV=1	200.0	[0..1]	[225..1]
KCY_VIBVU - Cytidylate kinase OS=Vibrio vulnificus GN=cmk PE=3 SV=1 KCY_VIBVU - Cytidylate kinase OS=Vibrio vulnificus (strain CMCP6) GN=cmk PE=3 SV=1	199.0	[0..1]	[225..1]
gi\|54309616, gi\|... - gi\|54309616\|ref\|YP_130636.1\| cytidylate kinase [Photobacterium profundum SS9], gi\|46914054\|emb\|CAG20...	199.0	[0..1]	[226..16]
gi\|37198227, gi\|... - gi\|37679483\|ref\|NP_934092.1\| cytidylate kinase [Vibrio vulnificus YJ016], gi\|37198227\|dbj\|BAC94063.1...	199.0	[0..1]	[225..5]
KCY_VIBF1 - Cytidylate kinase OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=cmk PE=3 SV=1	198.0	[0..1]	[224..1]

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Predicted Domain #1

Region A:
Residues: [1-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAIAPVITI DGPSGAGKGT LCKAMAEALQ WHLLDSGAIY RVLALAALHH HVDVASEDAL  60
   61 VPLASHLDVR FVSTNGNLEV ILEGEDVSGE IRTQEVANAA SQVAAFPRVR EALLRRQRAF 120
  121 RELPGLIADG RDMGTVVFPD APVKIFLDAS SEERAHRRML QLQEKGFSVN FERLLAEIKE 180
  181 RDDRDRNRAV APLVPAADAL VLDSTTLSIE QVIEKALQYA RQKLALA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.39794
Match:	1kdoA
Description:	CMP kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	3.11888266429063	bayes_pls_golite062009
nucleotide kinase activity	2.48123045432095	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	2.17027410710981	bayes_pls_golite062009
catalytic activity	1.37148167194523	bayes_pls_golite062009
kinase activity	1.24171059767741	bayes_pls_golite062009
binding	0.556857559334679	bayes_pls_golite062009
hydrolase activity	0.310795123901245	bayes_pls_golite062009
adenylate kinase activity	0.03629044845139	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: