YRC Public Data Repository - Protein Structure Prediction

Protein:	K1PF_ECOLI
Organism:	Escherichia coli
Length:	312 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for K1PF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|28203058, gi\|... - gi\|28210620\|ref\|NP_781564.1\| ribokinase [Clostridium tetani E88], gi\|28203058\|gb\|AAO35501.1\| ribokin...	241.0	[0..1]	[305..1]
gi\|49612178, gi\|... - gi\|50121652\|ref\|YP_050819.1\| 1-phosphofructokinase [Pectobacterium atrosepticum SCRI1043], gi\|496121... gi\|253688040, gi... - gi\|253688040\|ref\|YP_003017230.1\| 1-phosphofructokinase [Pectobacterium carotovorum subsp. carotovoru... gi\|227112072 - gi\|227112072\|ref\|ZP_03825728.1\| 1-phosphofructokinase [Pectobacterium carotovorum subsp. brasiliensi... gi\|227325882 - gi\|227325882\|ref\|ZP_03829906.1\| 1-phosphofructokinase [Pectobacterium carotovorum subsp. carotovorum...	232.0	[0..1]	[312..1]
gi\|75823229, gi\|... - gi\|75823229\|ref\|ZP_00752747.1\| COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate... tr\|D7HCF6\|D7HCF6... - Phosphofructokinase OS=Vibrio cholerae RC385 GN=VCRC385_03019 PE=3 SV=1	229.0	[0..1]	[312..1]
gi\|147672155, gi... - gi\|75825342\|ref\|ZP_00754778.1\| COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate...	229.0	[0..1]	[312..1]
gi\|194539703, gi... - gi\|75857156\|ref\|ZP_00764774.1\| COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate...	228.0	[0..2]	[311..5]
gi\|82500791, gi\|... - gi\|82500791\|ref\|ZP_00886188.1\| fructose-1-phosphate kinase and related fructose-6-phosphate kinase (...	228.0	[0..4]	[311..1]
gi\|227812086, gi... - gi\|227812086\|ref\|YP_002812096.1\| 1-phosphofructokinase [Vibrio cholerae M66-2], gi\|227011228\|gb\|ACP0... gi\|229506311, gi... - gi\|229506311\|ref\|ZP_04395820.1\| tagatose-6-phosphate kinase/1-phosphofructokinase [Vibrio cholerae B... gi\|121549326, gi... - gi\|121586501\|ref\|ZP_01676288.1\| 1-phosphofructokinase [Vibrio cholerae 2740-80], gi\|121549326\|gb\|EAX... gi\|229346491, gi... - gi\|229516610\|ref\|ZP_04406057.1\| tagatose-6-phosphate kinase/1-phosphofructokinase [Vibrio cholerae R... gi\|153220892, gi... - gi\|153220892\|ref\|ZP_01951974.1\| 1-phosphofructokinase [Vibrio cholerae MAK 757], gi\|124120120\|gb\|EAY... gi\|229605862, gi... - gi\|229605862\|ref\|YP_002876566.1\| tagatose-6-phosphate kinase/1-phosphofructokinase [Vibrio cholerae ... gi\|153819573, gi... - gi\|153819573\|ref\|ZP_01972240.1\| 1-phosphofructokinase [Vibrio cholerae NCTC 8457], gi\|126509883\|gb\|E... gi\|153820954, gi... - gi\|229509569\|ref\|ZP_04399051.1\| tagatose-6-phosphate kinase/1-phosphofructokinase [Vibrio cholerae B... gi\|15601277, gi\|... - gi\|9657922\|gb\|AAF96420.1\| 1-phosphofructokinase [Vibrio cholerae O1 biovar eltor str. N16961], gi\|15... gi\|11259262 - pir\|\|C82450 1-phosphofructokinase VCA0517 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|254849679, gi... - gi\|75830581\|ref\|ZP_00759856.1\| COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate... gi\|121726094, gi... - gi\|75816714\|ref\|ZP_00747176.1\| COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate...	227.0	[0..1]	[311..1]
gi\|116220536, gi... - gi\|75819827\|ref\|ZP_00749891.1\| COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate...	227.0	[0..1]	[312..1]
gi\|20515184, gi\|... - gi\|20806728\|ref\|NP_621899.1\| ribokinase family sugar kinase [Thermoanaerobacter tengcongensis MB4], ... gi\|20806728 - gi\|20806728\|ref\|NP_621899.1\| Sugar kinase, ribokinase family [Thermoanaerobacter tengcongensis MB4] gi\|254478103, gi... - gi\|254478103\|ref\|ZP_05091486.1\| ribokinase [Carboxydibrachium pacificum DSM 12653], gi\|223490092\|ref...	227.0	[0..3]	[305..1]
gi\|84385734, gi\|... - gi\|84385734\|ref\|ZP_00988764.1\| fructose-1-phosphate kinase [Vibrio splendidus 12B01], gi\|84379050\|gb...	226.0	[0..1]	[312..1]

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Predicted Domain #1

Region A:
Residues: [1-312]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRVATITL NPAYDLVGFC PEIERGEVNL VKTTGLHAAG KGINVAKVLK DLGIDVTVGG  60
   61 FLGKDNQDGF QQLFSELGIA NRFQVVQGRT RINVKLTEKD GEVTDFNFSG FEVTPADWER 120
  121 FVTDSLSWLG QFDMVCVSGS LPSGVSPEAF TDWMTRLRSQ CPCIIFDSSR EALVAGLKAA 180
  181 PWLVKPNRRE LEIWAGRKLP EMKDVIEAAH ALREQGIAHV VISLGAEGAL WVNASGEWIA 240
  241 KPPSVDVVST VGAGDSMVGG LIYGLLMRES SEHTLRLATA VAALAVSQSN VGITDRPQLA 300
  301 AMMARVDLQP FN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.69897
Match:	2abqA
Description:	Crystal structure of fructose-1-phosphate kinase from Bacillus halodurans
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.11518580948187	bayes_pls_golite062009
carbohydrate kinase activity	1.99025603598964	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.69918601153494	bayes_pls_golite062009
transferase activity	1.65599843675995	bayes_pls_golite062009
kinase activity	1.6060752218324	bayes_pls_golite062009
ribokinase activity	0.51718258191684	bayes_pls_golite062009
phosphofructokinase activity	0.14502182066038	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.143446029424335	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: